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Prior herpes zoster occurrence and high-dose corticosteroids increase herpes zoster risk in rheumatoid arthritis patients receiving janus kinase inhibitors in a retrospective and observational study

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  1. Article

    Open Access

    Assessing mortality risk in Type 2 Diabetes patients with prolonged ASCVD risk factors: the inclusive Poh-Ai predictive scoring system with CAC Score integration

    To enhance the predictive risk model for all-cause mortality in individuals with Type 2 Diabetes (T2DM) and prolonged Atherosclerotic Cardiovascular Disease (ASCVD) risk factors. Despite the utility of the Cor...

    Meng-Huan Lei, Yu-Chen Hsu, Sheng-Liang Chung in Diabetology & Metabolic Syndrome (2024)

  2. Article

    Open Access

    The association of socioeconomic status on kidney transplant access and outcomes: a nationwide cohort study in Taiwan

    Conflicting evidence exists regarding the relationship between socioeconomic status and access to or outcomes after kidney transplantation. This study analyzed the effects of individual and neighborhood socioe...

    Tung-Ling Chung, Nai-Ching Chen, Chun-Hao Yin, Ching-Chih Lee in Journal of Nephrology (2024)

  3. Article

    Open Access

    Patients with first-episode psychosis in northern Taiwan: neurocognitive performance and niacin response profile in comparison with schizophrenia patients of different familial loadings and relationship with clinical features

    Examining patients with first-episode psychosis (FEP) provides opportunities to better understand the mechanism underlying these illnesses. By incorporating quantitative measures in FEP patients, we aimed to (...

    Shun-Chun Yu, Tzung–Jeng Hwang, Chih-Min Liu, Hung-Yu Chan, Chian-Jue Kuo in BMC Psychiatry (2024)

  4. Article

    Open Access

    Different patterns of failure in two treatment regimens for primary central nervous system lymphoma, a retrospective analysis of 124 cases in Taiwan

    To explore prognostic factors and outcomes of primary central nervous system lymphoma (PCNSL) of diffuse large B-cell lymphoma (DLBCL) in Taiwan, 124 PCNSL-DLBCL patients (from 1995 to 2021) were retrospective...

    Chin-Hsuan Chuang, Ming-Chung Kuo, Hung Chang in Clinical and Experimental Medicine (2023)

  5. Article

    Open Access

    Late-onset symptomatic hyperprolactinemia in 6-pyruvoyl-tetrahydropterin synthase deficiency

    Tetrahydrobiopterin (BH4) deficiency caused by 6-pyruvoyl-tetrahydropterin synthase (PTPS) deficiency is a rare disorder that is one of the major causes of hyperphenylalaninemia in Taiwan.

    Rai-Hseng Hsu, Ni-Chung Lee, Hui-An Chen in Orphanet Journal of Rare Diseases (2023)

  6. Article

    Open Access

    A Streamlined Diagnostic Process Improved the Outcomes of Patients with Adult-Onset Still’s Disease: A Single-Center Retrospective Observational Study

    The diagnosis of adult-onset Still’s disease (AOSD) is often delayed due to its clinical heterogeneity and lack of pathognomic features. Hence, there is an unmet need for an efficient diagnostic process. The m...

    Shih-Hsin Chang, Teng-Chieh Hsu, Po-Hao Huang in Rheumatology and Therapy (2023)

  7. Article

    Open Access

    A Fc-VEGF chimeric fusion enhances PD-L1 immunotherapy via inducing immune reprogramming and infiltration in the immunosuppressive tumor microenvironment

    Immunotherapy is an emerging cancer therapy with potential great success; however, immune checkpoint inhibitor (e.g., anti-PD-1) has response rates of only 10–30% in solid tumor because of the immunosuppressive t...

    Cheng-Liang Kuo, Han-Yu Chou, Hui-Wen Lien, Chia-An Yeh in Cancer Immunology, Immunotherapy (2023)

  8. Article

    Open Access

    Chinese herbal medicines in the treatment of ulcerative colitis: a review

    To investigate how the ulcerative colitis (UC) be treated with Chinese herbal medicines (CHM), using Chinese medicine (CM) pattern (zheng) identification, in the current clinical practice.

    Xuan Zhang, Lin Zhang, Jacky C. P. Chan, **hong Wang, Chenchen Zhao in Chinese Medicine (2022)

  9. Article

    Correction to: The association between metabolic risk factors, nonalcoholic fatty liver disease, and the incidence of liver cancer: a nationwide population-based cohort study

    Yu-Guang Chen, Chih-Wei Yang, Chi-Hsiang Chung, Ching-Liang Ho in Hepatology International (2022)

  10. Article

    Open Access

    Smart clothes-assisted home-nursing care program for family caregivers of older persons with dementia and hip fracture: a mixed-methods study

    The purpose of this preliminary study was to explore whether a smart clothes-assisted home-nursing care program could benefit family caregivers and their care recipients.

    Yi-Jun Hou, Sih-Ying Zeng, Chung-Chih Lin, Ching-Tzu Yang in BMC Geriatrics (2022)

  11. Article

    Towards a safe hospital: hepatitis C in-hospital micro-elimination program (HCV-HELP study)

    Is hepatitis C virus (HCV) micro-elimination achievable at the hospital level with the structured strategies?

    Jee-Fu Huang, Ming-Yen Hsieh, Yu-Ju Wei, Jen-Yu Hung in Hepatology International (2022)

  12. Article

    Open Access

    Survival and diagnostic age of 175 Taiwanese patients with mucopolysaccharidoses (1985–2019)

    Mucopolysaccharidoses (MPSs) are a group of inherited metabolic diseases, which are characterized by the accumulation of glycosaminoglycans, and eventually lead to the progressive damage of various tissues and...

    Hsiang-Yu Lin, Chung-Lin Lee, Chia-Ying Chang in Orphanet Journal of Rare Diseases (2020)

  13. Article

    Open Access

    PRISMA extension for moxibustion 2020: recommendations, explanation, and elaboration

    Moxibustion is a common intervention of Chinese medicine (CM). Systematic reviews (SRs) on moxibustion are increasing. Although the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) s...

    Xuan Zhang, Ran Tan, Wai Ching Lam, Chung Wah Cheng, Liang Yao in Systematic Reviews (2020)

  14. Article

    Open Access

    Increased risk of knee osteoarthritis in patients using oral N-acetylcysteine: a nationwide cohort study

    Knee osteoarthritis (OA) is known to be a progressive degenerative disorder; however, recent evidence suggests that inflammatory mediators contribute to cartilage degradation. Studies have reported that N-acet...

    Ying-Ting Yeh, Chung-Chao Liang, Chia-Ling Chang in BMC Musculoskeletal Disorders (2020)

  15. Article

    Open Access

    Cumulative use of therapeutic bladder anticholinergics and the risk of dementia in patients with lower urinary tract symptoms: a nationwide 12-year cohort study

    Studies have shown an association between lower urinary tract symptoms (LUTS) and an increased risk of dementia. Whether anticholinergic use contributes to the development of dementia in patients with LUTS rem...

    Yi-Chi Wang, Yung-Liang Chen, Chun-Che Huang, Chung-Han Ho, Yu-Tung Huang in BMC Geriatrics (2019)

  16. Article

    Open Access

    The efficacy of limited endoscopic sphincterotomy plus endoscopic papillary large balloon dilation for removal of large bile duct stones

    The removal of large bile duct stones (> 15 mm) by conventional endoscopic sphincterotomy (EST) and endoscopic papillary balloon dilation (EPBD) can be challenging, requiring mechanical lithotripsy (ML) in add...

    Chung-Mou Kuo, Yi-Chun Chiu, Chih-Ming Liang, Cheng-Kun Wu in BMC Gastroenterology (2019)

  17. Article

    Open Access

    HOXA9 is a novel myopia risk gene

    A recent meta-analysis revealed PAX6 as a risk gene for myopia. There is a link between PAX6 and HOXA9. Furthermore, HOXA9 has been reported to activate TGF-β that is a risk factor for myopia. We speculate HOXA9 ...

    Chung-Ling Liang, Po-Yuan Hsu, Cheryl S. Ngo, Wei Jie Seow in BMC Ophthalmology (2019)

  18. Article

    Open Access

    Prescription patterns of traditional Chinese medicine amongst Taiwanese children: a population-based cohort study

    Traditional Chinese medicine (TCM) has been used by Chinese patients and in many other countries worldwide. However, epidemiological reports and prescription patterns on children are few.

    Hwey-Fang Liang, Yao-Hsu Yang, Pau-Chung Chen in BMC Complementary and Alternative Medicine (2018)

  19. Article

    Open Access

    Erratum to: Impact of metabolic syndrome and its components on heart rate variability during hemodialysis: a cross-sectional study

    Yu-Ming Chang, Chih-Chung Shiao, Ya-Ting Huang, I-Ling Chen in Cardiovascular Diabetology (2017)

  20. Article

    Open Access

    Correlation of blood bone turnover biomarkers and Wnt signaling antagonists with AS, DISH, OPLL, and OYL

    Wnt signaling plays an important role in development and maintenance of many organs and tissues. The most-studied secreted Wnt inhibitors are sclerostin (SOST), Dickkopf-related protein 1 (DKK-1), and secreted...

    Chi-Chien Niu, Song-Shu Lin, Li-Jen Yuan, Lih-Huei Chen in BMC Musculoskeletal Disorders (2017)

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