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Open AccessPredicting synthetic lethal genetic interactions in Saccharomyces cerevisiae using short polypeptide clusters
Protein synthetic lethal genetic interactions are useful to define functional relationships between proteins and pathways. However, the molecular mechanism of synthetic lethal genetic interactions remains uncl...
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Article
Open AccessAnalysis of the genomic sequence of Philosamia cynthia nucleopolyhedrin virus and comparison with Antheraea pernyinucleopolyhedrin virus
Two species of wild silkworms, the Chinese oak silkworm (Antheraea pernyi) and the castor silkworm Philosamia cynthia ricini, can acquire a serious disease caused by Nucleopolyhedrin Viruses (NPVs) (known as Anpe...
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Article
Screening of high toxic Metarhizium strain against Plutella xylostella and its marking with green fluorescent protein
Entomopathogenic fungus is proposed to be one of the best biocontrol agents against the destructive insect pest Plutella xylostella. In this study, we tested the virulence of 11 Metarhizium strain isolates agains...
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Article
Open AccessPostzygotic single-nucleotide mosaicisms in whole-genome sequences of clinically unremarkable individuals
Postzygotic single-nucleotide mutations (pSNMs) have been studied in cancer and a few other overgrowth human disorders at whole-genome scale and found to play critical roles. However, in clinically unremarkabl...
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Article
Breakdown of Rlm3 resistance in the Brassica napus–Leptosphaeria maculans pathosystem in western Canada
Blackleg disease, caused by the fungal pathogen Leptosphaeria maculans, is a serious disease of Brassica napus. The disease is mainly controlled by genetic resistance and crop rotation. However, L. maculans has d...
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Article
Open AccessComparative transcriptome sequencing and de novo analysis of Vaccinium corymbosum during fruit and color development
Blueberry is an economically important fruit crop in Ericaceae family. The substantial quantities of flavonoids in blueberry have been implicated in a broad range of health benefits. However, the information r...
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Article
Open AccessImprovement of phylogenetic method to analyze compositional heterogeneity
Phylogenetic analysis is a key way to understand current research in the biological processes and detect theory in evolution of natural selection. The evolutionary relationship between species is generally ref...
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Article
The cellular pathway and enzymatic activity for phloem-unloading transition in develo** Camellia oleifera Abel. Fruit
The phloem-unloading pathway of sucrose and mechanism of sugar-to-oil transition are still unknown in Camellia oleifera Fruit. Here, transmission electronic microscopy (TEM) and confocal laser-scanning microscopy...
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Article
Open AccessComparative transcriptomic analysis of resistant and susceptible alfalfa cultivars (Medicago sativa L.) after thrips infestation
Plant breeding for resistance to agricultural pests is an essential element in the development of integrated crop management systems; however, the molecular and genetic mechanisms underlying resistance are poo...
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Article
Open AccessDetecting complexes from edge-weighted PPI networks via genes expression analysis
Identifying complexes from PPI networks has become a key problem to elucidate protein functions and identify signal and biological processes in a cell. Proteins binding as complexes are important roles of life...
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Article
Picea wilsonii transcription factor NAC2 enhanced plant tolerance to abiotic stress and participated in RFCP1-regulated flowering time
Picea wilsonii transcription factor PwNAC2 enhanced plant tolerance to salt and drought stress through multiple signaling pathway and interacted with PwRFCP1 to participate in flowering regulation.
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Article
Decreasing sulfide in sediment and promoting plant growth by plant–sediment microbial fuel cells with emerged plants
Four plant–sediment microbial fuel cells (plant-SMFCs) with four plant species, Oryza sativa, Acorus calamus, Spathiphyllum petite and Chamaedorea elegans, were built to investigate sulfide concentrations, pH and...
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Article
Open AccessPlant composition changes in a small-scale community have a large effect on the performance of an economically important grassland pest
The grasshopper Oedaleus asiaticus Bey-Bienko (Acrididae: Oedipodinae) is a dominant and economically important pest that is widely distributed across the Mongolian plateau. This herbivore pest causes major damag...
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Article
Comparative Efficacy of Leaf Extracts of Different Tobacco Varieties Against Mustard Aphid (Lipaphis erysimi Kalt.)
In this study, field and laboratory experiments were carried out in order to develop a biological control strategy against mustard aphid by using extracts of five tobacco varieties (Beeri wala, Balkhi, Pattay ...
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Article
Open AccessIdentification of resistance loci in Chinese and Canadian canola/rapeseed varieties against Leptosphaeria maculans based on genome-wide association studies
The fungal pathogen Leptosphaeria maculans (Lm). causes blackleg disease on canola/rapeseed in many parts of the world. It is important to use resistant cultivars to manage the disease and minimize yield losses. ...
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Article
Inhibitory effect of genistein and PTP1B on grasshopper Oedaleus asiaticus development
Protein tyrosine kinase (PTKs) and protein tyrosine phosphatase (PTPs) collectively regulate the insect insulin-signaling pathway (ISP), cell growth, metabolism, proliferation, differentiation, cell communicat...
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Article
The survival, growth, and detoxifying enzyme activities of grasshoppers Oedaleus asiaticus (Orthoptera: Acrididae) exposed to toxic rutin
Secondary compounds from plants are often insecticidal. Rutin, a plant bioflavonoid, has demonstrated insect control activity. We studied the survival, growth, and detoxifying enzyme activities of grasshopper Oed...
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Article
Open AccessDeconstructing transcriptional variations and their effects on immunomodulatory function among human mesenchymal stromal cells
Mesenchymal stromal cell (MSC)-based therapies are being actively investigated in various inflammatory disorders. However, functional variability among MSCs cultured in vitro will lead to distinct therapeutic ...
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Article
The downregulation of PpPG21 and PpPG22 influences peach fruit texture and softening
The downregulation of PpPG21 and PpPG22 expression in melting-flesh peach delays fruit softening and hinders texture changes by influencing pectin solubilization and depolymerization.
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Article
Circular RNA circ-CHI3L1.2 modulates cisplatin resistance of osteosarcoma cells via the miR-340-5p/LPAATβ axis
Resistance to chemotherapy drugs is a major factor affecting the surgical outcome and prognosis of osteosarcoma patients. Circular RNAs (circRNAs) play an important role in tumor resistance to chemotherapy. In...