311 Result(s)
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Article
Interactions of the Novel Antipsychotic Aripiprazole (OPC-14597) with Dopamine and Serotonin Receptor Subtypes
OPC-14597 {aripiprazole; 7-(4-(4-(2,3-dichlorophenyl)-1-piperazinyl)butyloxy)-3,4-dihydro-2(1H)-quinolinone} is a novel candidate antipsychotic that has high affinity for striatal dopamine D2-like receptors, but ...
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Article
Open AccessFingerprint Reference-Point Detection
A robust fingerprint recognition algorithm should tolerate the rotation and translation of the fingerprint image. One popular solution is to consistently detect a unique reference point and compute a unique re...
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Chapter and Conference Paper
The Reuse Study of Small Agricultural Machinery’s Product Information Model
It is estimated that more than 90% of industrial design activity is based on variant design. How to use the product information model of similar products and to improve design efficiency and the designer’s cre...
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Chapter and Conference Paper
Axiomatic Design Using Ontology Modeling for Interoperability in Small Agriculture Machinery Product Development
Small Agricultural machinery (SAM) is applied widely in agriculture, forestry and stockbreeding. We focus the reconfiguration and Interoperability of the complex process of SAM product development, and propose...
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Chapter and Conference Paper
Implementation Evaluation Modeling of Selecting ERP Software Based on Fuzzy Theory
Selecting ERP software is a key strategy for enterprises to fully succeed in ERP practice. In this paper, the problem of Chinese medium-sized and small enterprises software selection is a lack of scientific an...
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Chapter and Conference Paper
An Interactive Robot Butler
This paper describes a novel robotic butler, developed by a multi-disciplinary team of researchers. The robotic butler is capable of detecting and tracking human, recognize hand gestures, serving beverages and...
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Article
Detection of gas reservoirs by the joint use of P- and PS-waves: A case study on the Ordos basin, China
We present an example of using converted-waves for characterizing onshore gas reservoirs in the Ordos basin in Northwest China. The Ordos basin is the largest gas province in China. The main gas reservoirs (ab...
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Article
MS80, a novel sulfated oligosaccharide, inhibits pulmonary fibrosis by targeting TGF-β1 both in vitro and in vivo
The pro-fibrogenic cytokine transforming growth factor-beta 1 (TGF-β1) has attracted much attention for its potential role in the etiology of idiopathic pulmonary fibrosis (IPF). Here, we demonstrate that MS80...
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Article
Open AccessMimotopes selected with a neutralizing antibody against urease B from Helicobacter pyloriinduce enzyme inhibitory antibodies in mice upon vaccination
Urease B is an important virulence factor that is required for Helicobacter pylori to colonise the gastric mucosa. Mouse monoclonal antibodies (mAbs) that inhibit urease B enzymatic activity will be useful as vac...
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Article
Erratum to: Grazers and vitamins shape chain formation in a bloom-forming dinoflagellate, Cochlodinium polykrikoides
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Article
Variables affecting leakage past endotracheal tube cuffs: a bench study
Leakage of oral secretions past endotracheal tubes (ETT) has been implicated in ventilator associated pneumonia. The aim of this bench study was to compare the ability of current generation ETT cuffs to preven...
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Article
Open AccessThe cellular source for APOBEC3G's incorporation into HIV-1
Human APOBEC3G (hA3G) has been identified as a cellular inhibitor of HIV-1 infectivity. Viral incorporation of hA3G is an essential step for its antiviral activity. Although the mechanism underlying hA3G virio...
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Article
A novel class of geldanamycin derivatives as HCV replication inhibitors targeting on Hsp90: synthesis, structure–activity relationships and anti-HCV activity in GS4.3 replicon cells
A novel class of geldanamycin (GA) derivatives as hepatitis C virus (HCV) replication inhibitors has been synthesized and their anti-HCV activities were evaluated in GS4.3 HCV replicon cells. Most of the synth...
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Article
Open AccessOrigins of 1/f noise in nanostructure inclusion polymorphous silicon films
In this article, we report that the origins of 1/f noise in pm-Si:H film resistors are inhomogeneity and defective structure. The results obtained are consistent with Hooge's formula, where the noise parameter, α
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Article
Sulfated polymannuroguluronate inhibits Tat-induced SLK cell adhesion via a novel binding site, a KKR spatial triad
Sulfated polymannuroguluronate (SPMG), a candidate anti-AIDS drug, inhibited HIV replication and interfered with HIV entry into host T lymphocytes. SPMG has high binding affinity for the transactivating factor...
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Article
Open AccessBioactivities of berberine metabolites after transformation through CYP450 isoenzymes
Berberine (BBR) is a drug with multiple effects on cellular energy metabolism. The present study explored answers to the question of which CYP450 (Cytochrome P450) isoenzymes execute the phase-I transformation...
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Article
Open AccessImprovement of orbit determination for geostationary satellites with VLBI tracking
China’s COMPASS satellite navigation system consists of five or more geostationary (GEO) satellites. The roles of GEO satellites are to improve the regional user’s positioning accuracy and provide the continuo...
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Article
Open AccessRetraction Note: the cellular source for APOBEC3G's incorporation into HIV-1
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Article
Open AccessIdentification and characterization of a novel gene, c1orf109, encoding a CK2 substrate that is involved in cancer cell proliferation
In the present study we identified a novel gene, Homo Sapiens Chromosome 1 ORF109 (c1orf109, GenBank ID: NM_017850.1), which encodes a substrate of CK2. We analyzed the regulation mode of the gene, the expression...
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Article
Open AccessSilicon nanowires prepared by electron beam evaporation in ultrahigh vacuum
One-dimensional silicon nanowires (SiNWs) were prepared by electron beam evaporation in ultrahigh vacuum (UHV). The SiNWs can be grown through either vapor–liquid-solid (VLS) or oxide-assisted growth (OAG) mec...