311 Result(s)
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Open AccessNeutrophil-derived migrasomes are an essential part of the coagulation system
Migrasomes are organelles that are generated by migrating cells. Here we report the key role of neutrophil-derived migrasomes in haemostasis. We found that a large number of neutrophil-derived migrasomes exist...
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Open AccessCorrection: Recruitment of LEF1 by Pontin chromatin modifier amplifies TGFBR2 transcription and activates TGFβ/SMAD signalling during gliomagenesis
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Open AccessA deep learning-driven discovery of berberine derivatives as novel antibacterial against multidrug-resistant Helicobacter pylori
Helicobacter pylori (H. pylori) is currently recognized as the primary carcinogenic pathogen associated with gastric tumorigenesis, and its high prevalence and resistance make it difficult to tackle. A graph neur...
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Correction: Promotion of osteogenesis in BMSC under hypoxia by ATF4 via the PERK–eIF2α signaling pathway
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Open AccessMendelian randomization reveals association of gut microbiota with Henoch–Schönlein purpura and immune thrombocytopenia
Gut microbiota have been linked to immune thrombocytopenia (ITP) and Henoch–Schönlein purpura (HSP) in recent studies, but a cause-and-effect relationship is unclear. We used Mendelian randomization (MR) to as...
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Open AccessPrimitiveNet: decomposing the global constraints for referring segmentation
In referring segmentation, modeling the complicated constraints in the multimodal information is one of the most challenging problems. As the information in a given language expression and image becomes increa...
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Open AccessThe twisted path to sacredness: a grounded theory study of irrational religious orientation and its psycho-sociological implications
This research delves into the nuances, origins, and societal effects of irrational religious orientations within China’s Generation Z, employing grounded theory methodology for a comprehensive analysis. The fo...
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Open AccessDiffusion model-based probabilistic downscaling for 180-year East Asian climate reconstruction
As our planet is entering into the “global boiling” era, understanding regional climate change becomes imperative. Effective downscaling methods that provide localized insights are crucial for this target. Tra...
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Open AccessEngineering natural microbiomes toward enhanced bioremediation by microbiome modeling
Engineering natural microbiomes for biotechnological applications remains challenging, as metabolic interactions within microbiomes are largely unknown, and practical principles and tools for microbiome engine...
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Open AccessAuthor Correction: Wasted efforts of elite Marathon runners under a warming climate primarily due to atmospheric oxygen reduction
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Open AccessStructural mechanisms for binding and activation of a contact-quenched fluorophore by RhoBAST
The fluorescent light-up aptamer RhoBAST, which binds and activates the fluorophore–quencher conjugate tetramethylrhodamine-dinitroaniline with high affinity, super high brightness, remarkable photostability, ...
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Open AccessCritical learning from industrial catalysis for nanocatalytic medicine
Systematical and critical learning from industrial catalysis will bring inspiration for emerging nanocatalytic medicine, but the relevant knowledge is quite limited so far. In this review, we briefly summarize...
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Open AccessDiabetes and aortic dissection: unraveling the role of 3-hydroxybutyrate through mendelian randomization
In observational and experimental studies, diabetes has been reported as a protective factor for aortic dissection. 3-Hydroxybutyrate, a key constituent of ketone bodies, has been found to favor improvements i...
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Open AccessThe association between the triglyceride-glucose index and in-stent restenosis in patients undergoing percutaneous coronary intervention: a systematic review and meta-analysis
Insulin resistance (IR) can lead to cellular metabolic disorders, activation of oxidative stress, and endothelial dysfunction, contributing to in-stent restenosis (ISR). The triglyceride-glucose index (TyG ind...
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Open AccessWasted efforts of elite Marathon runners under a warming climate primarily due to atmospheric oxygen reduction
Meteorological conditions exert influences on sport performances via complex processes. Previous studies conventionally investigate the effects of weather conditions on marathon performance by following events...
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Open AccessUse of serum KL-6 and chest radiographic severity grade to predict 28-day mortality in COVID-19 patients with pneumonia: a retrospective cohort study
Coronavirus disease 2019 (COVID-19) has had a global social and economic impact. An easy assessment procedure to handily identify the mortality risk of inpatients is urgently needed in clinical practice. There...
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Correction to: Efficacy of rTMS in treating functional impairment in post‑stroke patients: a systematic review and meta‑analysis
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Open AccessGenetic fusion of CCL11 to antigens enhances antigenicity in nucleic acid vaccines and eradicates tumor mass through optimizing T-cell response
Nucleic acid vaccines have shown promising potency and efficacy for cancer treatment with robust and specific T-cell responses. Improving the immunogenicity of delivered antigens helps to extend therapeutic ef...
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Open AccessCorrection: Single-cell profiling reveals the trajectory of FOLR2-expressing tumor-associated macrophages to regulatory T cells in the progression of lung adenocarcinoma
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Open AccessThe interaction of perfluoroalkyl acids and a family history of diabetes on arthritis: analyses of 2011–2018 NHANES
Whether a family history of diabetes (FHD) and exposure to perfluoroalkyl acids (PFAAs) are correlated with an increased risk of develo** arthritis remains unclear. This cross-sectional study was conducted t...