67 Result(s)
within
**cheng Yu
Biomedicine, general
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Article
GA binding protein regulates interleukin 7 receptor α-chain gene expression in T cells
The interleukin 7 receptor α-chain (IL-7Rα) is essential for T cell development in both humans and mice and for B cell development in mice. Whereas the transcription factor PU.1 regulates IL-7Rα expression in ...
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Article
Effect of MDR1 gene polymorphism on progression of end-stage renal disease
P-glycoprotein is localized at the apical brush-border membrane of the proximal renal tubule and functions as extruding toxins and xenobiotics out of cells. The difference of P-glycoprotein's function resulted...
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Article
Modified biplanar open-wedge high tibial osteotomy with rigid locking plate to treat varus knee
To introduce and characterize the modified biplanar opening high tibial osteotomy with rigid fixation to treat varus knee in young and active patients.
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Article
Spectroscopic Properties, Energy Transfer and Structural Analysis of Sr2CeO4:M+ and Sr2CeO4:Eu3+,M+ (M+ = Li+, Na+, K+)
The room-temperature luminescent emission characteristics of Sr2CeO4:M+ and Sr2CeO4:Eu3+,M+ (M+ = Li+, Na+, K+) have been investigated under UV excitation. By introducing appropriate alkali metal cations dopants ...
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Article
A new plastic surgical technique for adult congenital webbed penis
To introduce a novel surgical technique for correction of adult congenital webbed penis.
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Article
Open AccessExpression of ERBB3 binding protein 1 (EBP1) in salivary adenoid cystic carcinoma and its clinicopathological relevance
ERBB3 binding protein 1 (EBP1) gene transfer into human salivary adenoid cystic carcinoma cells has been shown to significantly inhibit cell proliferation and reduce tumor metastasis in mouse models. In the curre...
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Article
Recent advances in the study of testicular nuclear receptor 4
Testicular nuclear receptor 4 (TR4), also known as NR2C2 (nuclear receptor subfamily 2, group C, member 2), is a transcriptional factor and a member of the nuclear receptor family. TR4 was initially cloned fro...
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Article
Sensory–sympathetic coupling in superior cervical ganglia after myocardial ischemic injury facilitates sympathoexcitatory action via P2X7 receptor
P2X receptors participate in cardiovascular regulation and disease. After myocardial ischemic injury, sensory–sympathetic coupling between rat cervical DRG nerves and superior cervical ganglia (SCG) facilitate...
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Article
High dose of extracellular ATP switched autophagy to apoptosis in anchorage-dependent and anchorage-independent hepatoma cells
Extracellular adenosine triphosphate (eATP) transduces purinergic signal and plays an important regulatory role in many biological processes, including tumor cell growth and cell death. A large amount of eATP ...
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Article
Genetic variations in TP53 binding sites are predictors of clinical outcomes in prostate cancer patients
Since the tumor protein p53 (TP53), a transcription factor, plays a crucial role in prostate cancer development and progression, we hypothesized that sequence variants in TP53 binding sites might affect clinic...
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Article
Dynamic observation of oxygen vacancies in hafnia layer by in situ transmission electron microscopy
The charge-trap** process, with HfO2 film as the charge-capturing layer, has been investigated by using in situ electron energy-loss spectroscopy and in situ energy-filter image under positive external bias. Th...
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Article
Application of created restriction site PCR-RFLP to identify POT1 gene polymorphism
Protection of telomeres protein 1 (POT1) plays pivotal roles in protection of chromosome ends and regulation of telomere length with other telomere binding proteins; its genetic polymorphisms are associated wi...
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Article
Hypoxia-Sensitive Materials for Biomedical Applications
Hypoxia is a typical hallmark of various diseases, including cancer, ischemic diseases, and stroke. It is also associated with the disease progression. Therefore, it is critical to develop an effective strateg...
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Article
High-pressure balloon dilation for male anterior urethral stricture: single-center experience
We retrospectively reviewed the urethral stricture cases treated in our tertiary center, and assessed the safety and feasibility of the high-pressure balloon dilation (HPBD) technique for anterior urethral str...
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Article
Discovery, synthesis, biological evaluation and structure-based optimization of novel piperidine derivatives as acetylcholine-binding protein ligands
The homomeric α7 nicotinic receptor (α7 nAChR) is widely expressed in the human brain that could be activated to suppress neuroinflammation, oxidative stress and neuropathic pain. Consequently, a number of α7 ...
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Article
Ultrasound-triggered noninvasive regulation of blood glucose levels using microgels integrated with insulin nanocapsules
Diabetes is a serious public health problem affecting 422 million people worldwide. Traditional diabetes management often requires multiple daily insulin injections, associated with pain and inadequate glycemi...
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Article
Open AccessConjugated polymer nanomaterials for theranostics
Conjugated polymer nanomaterials (CPNs), as optically and electronically active materials, hold promise for biomedical imaging and drug delivery applications. This review highlights the recent advances in the ...
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Article
Open AccessCan China achieve a one-third reduction in premature mortality from non-communicable diseases by 2030?
The United Nation’s Sustainable Development Goals for 2030 include reducing premature mortality from non-communicable diseases (NCDs) by one third. To assess the feasibility of this goal in China, we projected...
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Article
Giant enhancement and anomalous temperature dependence of magnetism in monodispersed NiPt2 nanoparticles
A simple yet general one-step solvothermal method is applied to synthesize sub-7 nm monodispersed single-crystal NiPt2 nanoparticles (NPs) with the morphology of truncated octahedrons in the alloying state of dis...
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Article
Population pharmacokinetics and Bayesian estimation of mycophenolic acid concentrations in Chinese adult renal transplant recipients
Mycophenolate mofetil (MMF) is an important immunosuppressant used in renal transplantation, and mycophenolic acid (MPA) is the active component released from the ester prodrug MMF. The objective of this study...
