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**bo Zan
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Article
Investigating the Impact of Ocean Acidification on Anti-Stress Mechanisms in Sepia esculenta Larvae Based on Transcriptome Profiling
With the rapid development of oil, energy, power and other industries, CO2 emissions rise sharply, which will cause a large amount of CO2 in the air be absorbed by the ocean and lead to ocean acidification. The g...
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Open AccessDeletion of GPR81 activates CREB/Smad7 pathway and alleviates liver fibrosis in mice
Enhanced glycolysis is a crucial metabolic event that drives the development of liver fibrosis, but the molecular mechanisms have not been fully understood. Lactate is the endproduct of glycolysis, which has r...
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Effect of Al2O3 on the Mechanical Properties of (B4C + Al2O3)/Al Neutron Absorbing Materials
B4C/Al composites are widely utilized as neutron absorbing materials for the storage and transportation of spent nuclear fuel. In order to improve the high-temperature mechanical properties of B4C/Al composites, ...
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Evaluation of the efficacy of autogenous tibial periosteal bone grafting in the treatment of osteochondral lesions of the talus and analysis of three-dimensional factors in the necrotic zone
This study aims to explore the clinical value of autogenous tibial periosteal bone grafting in the treatment of osteochondral lesions of the talus (OLT) and analyze the three-dimensional factors in the necroti...
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Posterior intra-articular distraction technique to treat pediatric atlantoaxial instability
Surgical treatment for atlantoaxial instability in pediatric patients is challenging. We report our experience with posterior intra-articular distraction technique in treating this disorder.
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Research progress on TiO2-modified lithium and lithium-sulfur battery separator materials
With the increasing promotion of new energy vehicles and the rapid popularization of digital electronic products, there is a growing demand for lithium-ion and lithium-sulfur batteries. These batteries have ga...
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Dual-trait genomic analysis in highly stratified Arabidopsis thaliana populations using genome-wide association summary statistics
Genome-wide association study (GWAS) is a powerful tool to identify genomic loci underlying complex traits. However, the application in natural populations comes with challenges, especially power loss due to p...
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Alterations in Serum Lipids and Lipoproteins Induced by Neoadjuvant Chemotherapy in Patients with Osteosarcoma around the Knee Joint: A Retrospective Analysis
To investigate the serum lipid profiles of patients with localized osteosarcoma around the knee joint before and after neoadjuvant chemotherapy.
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Open AccessEvaluation of the immunogenicity and protective efficacy of an inactivated vaccine candidate for sheep infected with ovine parainfluenza virus type 3
Respiratory diseases constitute a major health problem for ruminants, resulting in considerable economic losses throughout the world. Parainfluenza type 3 virus (PIV3) is one of the most important respiratory ...
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Cognitive impairment associated with individual and joint exposure to PM2.5 constituents in a Chinese national cohort
Nationwide longitudinal evidence linking cognitive decline with exposure to fine particulate matter (PM2.5) constituents remains scarce in China. By constructing a dynamic cohort based on the China Health and Ret...
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Open AccessFrequency-dependent selection of neoantigens fosters tumor immune escape and predicts immunotherapy response
Cancer is an evolutionary process shaped by selective pressure from the microenvironments. However, recent studies reveal that certain tumors undergo neutral evolution where there is no detectable fitness diff...
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Open AccessA humanized mouse that mounts mature class-switched, hypermutated and neutralizing antibody responses
Humanized mice are limited in terms of modeling human immunity, particularly with regards to antibody responses. Here we constructed a humanized (THX) mouse by grafting non-γ-irradiated, genetically myeloablated
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Pancancer Analysis of NSUN2 with a Focus on Prognostic and Immunological Roles in Endometrial Cancer
The significance of NSUN2 in carcinogenesis is gradually being recognized, yet a comprehensive analysis across pan-cancer remains a pivotal void in existing research. In our investigation, we capitalized on th...
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Preparation and Adsorption Performance of Polyvinyl Chloride/Polyacrylonitrile Blended Lithium Ion-Sieve Membrane
To address the limitations of ion-sieve powder in industrial applications and to facilitate the industrial application of lithium extraction through ion sieves, this study utilized the solvent exchange method ...
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Open AccessAdvanced optical assessment and modeling of extrusion bioprinting
In the context of tissue engineering, biofabrication techniques are employed to process cells in hydrogel-based matrices, known as bioinks, into complex 3D structures. The aim is the production of functional t...
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Synthesis of reduced graphene oxide-fungal hyphae biochar/iron oxide composite: characterization, adsorption performance, and removal mechanisms
In this study, a novel biochar, iron-impregnated reduced graphene oxide-fungal hyphae, named AOBC-rGO, was synthesized as an innovative approach for the removal of Cr(VI) ions from water. A scanning electron m...
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Open AccessExploring e-sports fans’ motivation for watching live streams based on self-determination theory
This study seeks to examine the multifaceted influences of diverse motivational factors on the live streaming engagement of e-sports fans based on self-determination theory. While previous research has focused...
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Open AccessStudy on different isolation technology on the performance of blue micro-LEDs array applications
In this study, a 3 × 3 blue micro-LED array with a pixel size of 10 × 10 μm2 and a pitch of 15 μm was fabricated on an epilayer grown on a sapphire substrate using metalorganic chemical vapor deposition technolog...
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Open AccessNeoadjuvant chemotherapy-induced hemoglobin decline as a prognostic factor in osteosarcoma around the knee joint: a single-center retrospective analysis of 242 patients
Anemia is relatively common in cancer patients, and is associated with poor survival in patients with various malignancies. However, how anemia would affect prognosis and response to neoadjuvant chemotherapy (...
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Open AccessGenome-wide analysis reveals genomic diversity and signatures of selection in Qinchuan beef cattle
Indigenous Chinese cattle have abundant genetic diversity and a long history of artificial selection, giving local breeds advantages in adaptability, forage tolerance and resistance. The detection of selective...
