38 Result(s)
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**aoyuan **a
Life Sciences
Plant Genetics and Genomics
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Article
Open AccessRecurrent neural network for predicting absence of heterozygosity from low pass WGS with ultra-low depth
The absence of heterozygosity (AOH) is a kind of genomic change characterized by a long contiguous region of homozygous alleles in a chromosome, which may cause human genetic disorders. However, no method of l...
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Open AccessComparative analysis of POD genes and their expression under multiple hormones in Pyrus bretschenedri
Class III peroxidase (POD) enzymes play vital roles in plant development, hormone signaling, and stress responses. Despite extensive research on POD families in various plant species, the knowledge regarding t...
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Open AccessPangenome-Wide Association Study and Transcriptome Analysis Reveal a Novel QTL and Candidate Genes Controlling both Panicle and Leaf Blast Resistance in Rice
Cultivating rice varieties with robust blast resistance is the most effective and economical way to manage the rice blast disease. However, rice blast disease comprises leaf and panicle blast, which are differ...
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Open AccessInfluence of the Cellular Ultrastructure and Enzyme Activity of the Leaf Sheath on Spontaneous Defoliation in Sugarcane
Spontaneous defoliation improves the harvesting efficiency and yield of sugarcane. Here, we investigated the ultrastructural changes and pectinase and cellulase activity in the third, fifth, and seventh leaf s...
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Open AccessData notes on the proteomics of Dendrobium huoshanense under pb treatment
Pb stress has a negative impact on plant growth by interfering with photosynthesis and releasing reactive oxygen species, causing major risks such as heavy metal ion accumulation in the soil matrix. A proteomi...
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Open AccessLong-read sequencing reveals the structural complexity of genomic integration of HPV DNA in cervical cancer cell lines
Cervical cancer (CC) causes more than 311,000 deaths annually worldwide. The integration of human papillomavirus (HPV) is a crucial genetic event that contributes to cervical carcinogenesis. Despite HPV DNA in...
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Open AccessGenomic characterization of Listeria monocytogenes and Listeria innocua isolated from milk and dairy samples in Ethiopia
Listeriosis caused by Listeria monocytogenes often poses a significant threat to vulnerable populations. Dairy products have been implicated in outbreaks of listeriosis worldwide. In Ethiopia, studies have identi...
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Open AccessA Mitochondrial Localized Chaperone Regulator OsBAG6 Functions in Saline-Alkaline Stress Tolerance in Rice
B-cell lymphoma 2 (Bcl-2)-associated athanogene (BAG) family genes play prominent roles in regulating plant growth, development, and stress response. Although the molecular mechanism underlying BAG’s response ...
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Open AccessGinsenoside Rh4 inhibits inflammation-related hepatocellular carcinoma progression by targeting HDAC4/IL-6/STAT3 signaling
This study aimed to investigate the effects of Ginsenoside Rh4 (Rh4) on inflammation-related hepatocellular carcinoma (HCC) progression and the underlying mechanism. HCC cells (HUH7 and LM3) were induced by li...
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Open AccessA novel SNP in NKX1-2 gene is associated with carcass traits in Dezhou donkey
At present, donkey meat in the market shows an imbalance between supply and demand, and there is an urgent need to cultivate a meat-type Dezhou donkey breed. On the one hand, it can improve the imbalance in th...
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Open AccessCompositional Shifts and Assembly in Rhizosphere-Associated Fungal Microbiota Throughout the Life Cycle of Japonica Rice Under Increased Nitrogen Fertilization
Soil fungal microbiomes facilitate a range of beneficial functions for their host plants, and rhizosphere fungal community composition, richness, and diversity affect plant growth and development, and crop yie...
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Open AccessIdentification of BBX gene family and its function in the regulation of microtuber formation in yam
BBX proteins play important roles in all of the major light-regulated developmental processes. However, no systematic analysis of BBX gene family regarding the regulation of photoperiodic microtuber formation has...
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Open AccessIdentification of lncRNA, miRNA and mRNA expression profiles and ceRNA Networks in small cell lung cancer
Small cell lung cancer (SCLC) is a highly lethal malignant tumor. It accounts for approximately 15% of newly diagnosed lung cancers. Long non-coding RNAs (lncRNAs) can regulate gene expression and contribute t...
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Open AccessPolymorphism detection of PRKG2 gene and its association with the number of thoracolumbar vertebrae and carcass traits in Dezhou donkey
Previous studies have shown that the protein kinase cGMP-dependent 2 (PRKG2) gene is associated with dwarfism in humans, dogo Argentines, and Angus cattle, as well as with height and osteoblastogenesis in humans....
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Open AccessIdentification of hub genes and pathways in colitis-associated colon cancer by integrated bioinformatic analysis
Colitis-associated colon cancer (CAC) patients have a younger age of onset, more multiple lesions and invasive tumors than sporadic colon cancer patients. Early detection of CAC using endoscopy is challenging,...
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Open AccessIntegrative QTL Identification, Fine Map** and Candidate Gene Analysis of a Major Locus qLTG3a for Seed Low-Temperature Germinability in Rice
Low-temperature germinability (LTG) is an important agronomic trait that can affect the planting time, planting area, and grain yield of staple crops, such as rice. However, the genetic mechanism of LTG is sti...
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Open AccessTranscriptome profiling of Malus sieversii under freezing stress after being cold-acclimated
Freezing temperatures are an abiotic stress that has a serious impact on plant growth and development in temperate regions and even threatens plant survival. The wild apple tree (Malus sieversii) needs to undergo...
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Open AccessSUPERGNOVA: local genetic correlation analysis reveals heterogeneous etiologic sharing of complex traits
Local genetic correlation quantifies the genetic similarity of complex traits in specific genomic regions. However, accurate estimation of local genetic correlation remains challenging, due to linkage disequil...
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Open AccessPUMAS: fine-tuning polygenic risk scores with GWAS summary statistics
Polygenic risk scores (PRSs) have wide applications in human genetics research, but often include tuning parameters which are difficult to optimize in practice due to limited access to individual-level data. H...
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Sorghum breeding in the genomic era: opportunities and challenges
The importance and potential of the multi-purpose crop sorghum in global food security have not yet been fully exploited, and the integration of the state-of-art genomics and high-throughput technologies into ...
