Skip to main content

and
  1. Article

    Open Access

    Recurrent neural network for predicting absence of heterozygosity from low pass WGS with ultra-low depth

    The absence of heterozygosity (AOH) is a kind of genomic change characterized by a long contiguous region of homozygous alleles in a chromosome, which may cause human genetic disorders. However, no method of l...

    Fei Tang, Zhonghua Wang, Yan Sun, Linlin Fan, Yun Yang, Xueqin Guo in BMC Genomics (2024)

  2. Article

    Open Access

    Long-read sequencing reveals the structural complexity of genomic integration of HPV DNA in cervical cancer cell lines

    Cervical cancer (CC) causes more than 311,000 deaths annually worldwide. The integration of human papillomavirus (HPV) is a crucial genetic event that contributes to cervical carcinogenesis. Despite HPV DNA in...

    Zhijie Wang, Chen Liu, Wanxin Liu, **nyi Lv, Ting Hu, Fan Yang, Wenhui Yang in BMC Genomics (2024)

  3. Article

    Open Access

    Identification of BBX gene family and its function in the regulation of microtuber formation in yam

    BBX proteins play important roles in all of the major light-regulated developmental processes. However, no systematic analysis of BBX gene family regarding the regulation of photoperiodic microtuber formation has...

    Yingying Chang, Haoyuan Sun, Shiyu Liu, Yulong He, Shanshan Zhao in BMC Genomics (2023)

  4. Article

    Open Access

    Identification of lncRNA, miRNA and mRNA expression profiles and ceRNA Networks in small cell lung cancer

    Small cell lung cancer (SCLC) is a highly lethal malignant tumor. It accounts for approximately 15% of newly diagnosed lung cancers. Long non-coding RNAs (lncRNAs) can regulate gene expression and contribute t...

    Chenxi Zhang, Ying Zhou, Bin Zhang, Zhihong Sheng, Nan Sun, Baiyin Yuan in BMC Genomics (2023)

  5. Article

    Open Access

    Transcriptome profiling of Malus sieversii under freezing stress after being cold-acclimated

    Freezing temperatures are an abiotic stress that has a serious impact on plant growth and development in temperate regions and even threatens plant survival. The wild apple tree (Malus sieversii) needs to undergo...

    ** Zhou, **aoshuang Li, **aojie Liu, Xue**g Wen, Yan Zhang in BMC Genomics (2021)

  6. Article

    Open Access

    Functional examination of lncRNAs in allotetraploid Gossypium hirsutum

    An evolutionary model using diploid and allotetraploid cotton species identified 80 % of non-coding transcripts in allotetraploid cotton as being uniquely activated in comparison with its diploid ancestors. Th...

    Luyao Wang, ** Han, Kening Lu, Menglin Li, Mengtao Gao, Zeyi Cao in BMC Genomics (2021)

  7. Article

    Open Access

    PacBio full-length transcriptome of wild apple (Malus sieversii) provides insights into canker disease dynamic response

    Valsa canker is a serious disease in the stem of Malus sieversii, caused by Valsa mali. However, little is known about the global response mechanism in M. sieversii to V. mali infection.

    **aojie Liu, **aoshuang Li, Xue**g Wen, Yan Zhang, Yu Ding, Yiheng Zhang in BMC Genomics (2021)

  8. Article

    Open Access

    Identification and expression analysis of GRAS transcription factors in the wild relative of sweet potato Ipomoea trifida

    GRAS gene is an important transcription factor gene family that plays a crucial role in plant growth, development, adaptation to adverse environmental condition. Sweet potato is an important food, vegetable, indu...

    Yao Chen, Panpan Zhu, Shaoyuan Wu, Yan Lu, Jian Sun, Qinghe Cao, Zongyun Li in BMC Genomics (2019)

  9. Article

    Open Access

    Comparative transcriptional analysis of Capsicum flower buds between a sterile flower pool and a restorer flower pool provides insight into the regulation of fertility restoration

    Cytoplasmic male sterility (CMS) and its restoration of fertility (Rf) system is an important mechanism to produce F1 hybrid seeds. Understanding the interaction that controls restoration at a molecular level wil...

    Bingqiang Wei, Lanlan Wang, Paul W. Bosland, Gaoyuan Zhang, Ru Zhang in BMC Genomics (2019)

  10. Article

    Open Access

    Landscape of transcriptional deregulation in lung cancer

    Lung cancer is a very heterogeneous disease that can be pathologically classified into different subtypes including small-cell lung carcinoma (SCLC), lung adenocarcinoma (LUAD), lung squamous cell carcinoma (L...

    Shu Zhang, Mingfa Li, Hongbin Ji, Zhaoyuan Fang in BMC Genomics (2018)

  11. Article

    Open Access

    De novo transcriptome characterization and gene expression profiling of the desiccation tolerant moss Bryum argenteum following rehydration

    The desiccation-tolerant moss Bryum argenteum is an important component of the Biological Soil Crusts (BSCs) found in the Gurbantunggut desert. Desiccation tolerance is defined as the ability to revive from the a...

    Bei Gao, Daoyuan Zhang, **aoshuang Li, Honglan Yang, Yuanming Zhang in BMC Genomics (2015)

  12. Article

    Open Access

    Global epigenomic analysis indicates that Epialleles contribute to Allele-specific expression via Allele-specific histone modifications in hybrid rice

    For heterozygous genes, alleles on the chromatin from two different parents exhibit histone modification variations known as allele-specific histone modifications (ASHMs). The regulation of allele-specific gen...

    Zhibin Guo, Gaoyuan Song, Zhenwei Liu, Xuefeng Qu, Rong Chen, Daiming Jiang in BMC Genomics (2015)

  13. Article

    Open Access

    The phenotypic predisposition of the parent in F1 hybrid is correlated with transcriptome preference of the positive general combining ability parent

    Sprague and Tatum (1942) introduced the concepts of general combining ability (GCA) and specific combining ability (SCA) to evaluate the breeding parents and F1 hybrid performance, respectively. Since then, th...

    Gaoyuan Song, Zhibin Guo, Zhenwei Liu, Xuefeng Qu, Daiming Jiang, Wei Wang in BMC Genomics (2014)

  14. Article

    Open Access

    Comparative Transcriptomes Profiling of Photoperiod-sensitive Male Sterile Rice Nongken 58S During the Male Sterility Transition between Short-day and Long-day

    Photoperiod-sensitive genic male sterile (PGMS) rice, Nongken 58S, was discovered in 1973. It has been widely used for the production of hybrid rice, and great achievements have been made in improving rice yie...

    Wei Wang, Zhenwei Liu, Zhibin Guo, Gaoyuan Song, Qin Cheng, Daiming Jiang in BMC Genomics (2011)