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  1. Article

    Open Access

    Cryo-EM structure of severe fever with thrombocytopenia syndrome virus

    The severe fever with thrombocytopenia syndrome virus (SFTSV) is a tick-borne human-infecting bunyavirus, which utilizes two envelope glycoproteins, Gn and Gc, to enter host cells. However, the structure and o...

    Shouwen Du, Ruchao Peng, Wang Xu, **aoyun Qu, Yuhang Wang in Nature Communications (2023)

  2. Article

    Correction to: Characterization of the microbial community and prediction of metabolic functions in an anaerobic/oxic system with magnetic micropolystyrene as a biocarrier

    Fengyuan Zhang, Ying Chen, **aoshuang Shi in Environmental Science and Pollution Resear… (2023)

  3. No Access

    Article

    Characterization of the microbial community and prediction of metabolic functions in an anaerobic/oxic system with magnetic micropolystyrene as a biocarrier

    Polystyrene (PS) and magnetic polystyrene (MPS) materials have been used extensively in wastewater treatment. In this research, a 55-day anaerobic/oxic process was carried out to evaluate the effects of PS and...

    Fengyuan Zhang, Ying Chen, **aoshuang Shi in Environmental Science and Pollution Resear… (2023)

  4. No Access

    Article

    Enhanced bio-affinity of magnetic QD-P(St-GMA)@Fe3O4 micro-particles via surface-quaternized modification

    In this work, a kind of bio-carrier quaternized-polystyrene-polyglycidyl methacrylate@Fe3O4 (QD-P(St-GMA)@Fe3O4, QD-PSGF) micro-particles was successfully prepared by modifying PSGF micro-particles through a hydr...

    Kang Qin, **aoshuang Shi, Ying Chen in Environmental Science and Pollution Resear… (2023)

  5. No Access

    Article

    Why does batch normalization induce the model vulnerability on adversarial images?

    Batch normalization is one of the most widely used components in deep neural networks. It can accelerate training, and boost model performance on normal samples. However, batch normalization induces vulnerabil...

    Fei Kong, Fangqi Liu, Kaidi Xu, **aoshuang Shi in World Wide Web (2023)

  6. No Access

    Chapter and Conference Paper

    Co-assistant Networks for Label Correction

    The presence of corrupted labels is a common problem in the medical image datasets due to the difficulty of annotation. Meanwhile, corrupted labels might significantly deteriorate the performance of deep neura...

    Xuan Chen, Weiheng Fu, Tian Li in Medical Image Computing and Computer Assis… (2023)

  7. No Access

    Chapter and Conference Paper

    Segment Membranes and Nuclei from Histopathological Images via Nuclei Point-Level Supervision

    Accurate segmentation and analysis of membranes from immunohistochemical (IHC) images are crucial for cancer diagnosis and prognosis. Although several fully-supervised deep learning methods for membrane segmen...

    Hansheng Li, Zhengyang Xu, Mo Zhou in Medical Image Computing and Computer Assis… (2023)

  8. Article

    Open Access

    Traditional Chinese medicine based on Tongjiang methodology combined with proton pump inhibitor (PPI) step-down in treating non-erosive reflux disease: a study protocol for a multicentered, randomized controlled clinical trial

    Non-erosive reflux disease (NERD) is characterized by typical gastroesophageal reflux symptoms, such as heartburn and regurgitation but an absence of esophageal mucosal damage during upper gastrointestinal end...

    **a Li, Haomeng Wu, Beihua Zhang, Ting Chen, **aoshuang Shi, **xin Ma in Trials (2022)

  9. No Access

    Chapter and Conference Paper

    Dual-Graph Learning Convolutional Networks for Interpretable Alzheimer’s Disease Diagnosis

    In this paper, we propose a dual-graph learning convolutional network (dGLCN) to achieve interpretable Alzheimer’s disease (AD) diagnosis, by jointly investigating subject graph learning and feature graph lear...

    Tingsong **ao, Lu Zeng, **aoshuang Shi in Medical Image Computing and Computer Assis… (2022)

  10. No Access

    Article

    Anchor-Based Self-Ensembling for Semi-Supervised Deep Pairwise Hashing

    Deep hashing has attracted considerable attention to tackle large-scale retrieval tasks, because of automatic and powerful feature extraction of convolutional neural networks and the gain of hashing in computa...

    **aoshuang Shi, Zhenhua Guo, Fuyong **ng in International Journal of Computer Vision (2020)

  11. No Access

    Chapter and Conference Paper

    A Novel Loss Calibration Strategy for Object Detection Networks Training on Sparsely Annotated Pathological Datasets

    Recently, object detection frameworks based on Convolutional Neural Networks (CNNs) have become powerful methods for various tasks of medical image analysis; however, they often struggle with most pathological...

    Hansheng Li, **n Han, Yuxin Kang in Medical Image Computing and Computer Assis… (2020)

  12. Article

    Open Access

    Investigating Various Factors Affecting the Long-Term Compressive Strength of Heat-Cured Fly Ash Geopolymer Concrete and the Use of Orthogonal Experimental Design Method

    This work quantified the hierarchy of the influence of three common mixture design parameters on the compressive strength and the rate of strength increase over the long term of low-calcium fly ash geopolymer ...

    Hongen Zhang, Lang Li, Prabir Kumar Sarker in International Journal of Concrete Structur… (2019)

  13. Article

    Open Access

    Correction to: Towards pixel-to-pixel deep nucleus detection in microscopy images

    Following publication of the original article [1], we have been notified of a few errors in the html version:

    Fuyong **ng, Yuanpu **e, **aoshuang Shi, **jun Chen, Zizhao Zhang in BMC Bioinformatics (2019)

  14. Article

    Open Access

    Towards pixel-to-pixel deep nucleus detection in microscopy images

    Nucleus or cell detection is a fundamental task in microscopy image analysis and supports many other quantitative studies such as object counting, segmentation, tracking, etc. Deep neural networks are emerging...

    Fuyong **ng, Yuanpu **e, **aoshuang Shi, **jun Chen, Zizhao Zhang in BMC Bioinformatics (2019)

  15. Article

    Publisher Correction: Pathologist-level interpretable whole-slide cancer diagnosis with deep learning

    An amendment to this paper has been published and can be accessed via a link at the top of the paper.

    Zizhao Zhang, **jun Chen, Mason McGough, Fuyong **ng in Nature Machine Intelligence (2019)

  16. Article

    Publisher Correction: Pathologist-level interpretable whole-slide cancer diagnosis with deep learning

    An amendment to this paper has been published and can be accessed via a link at the top of the paper

    Zizhao Zhang, **jun Chen, Mason McGough, Fuyong **ng in Nature Machine Intelligence (2019)

  17. No Access

    Article

    Pathologist-level interpretable whole-slide cancer diagnosis with deep learning

    Diagnostic pathology is the foundation and gold standard for identifying carcinomas. However, high inter-observer variability substantially affects productivity in routine pathology and is especially ubiquitou...

    Zizhao Zhang, **jun Chen, Mason McGough, Fuyong **ng in Nature Machine Intelligence (2019)

  18. Article

    Open Access

    Combination of 15 lipid metabolites and motilin to diagnose spleen-deficiency FD

    This study aims to assess clinical characteristics in FD with spleen deficiency syndrome and metabolic perturbations involved in FD progress. We combined metabolic biomarkers and clinical features into a bette...

    Jiaqi Zhang, Xue Wang, **aoshuang Shi, **gyi **e, Min Zhang, **xin Ma in Chinese Medicine (2019)

  19. No Access

    Chapter and Conference Paper

    Local and Global Consistency Regularized Mean Teacher for Semi-supervised Nuclei Classification

    Nucleus classification is a fundamental task in pathology diagnosis for cancers, e.g., Ki-67 index estimation. Supervised deep learning methods have achieved promising classification accuracy. However, the succes...

    Hai Su, **aoshuang Shi, **zheng Cai in Medical Image Computing and Computer Assis… (2019)

  20. No Access

    Chapter

    Deep Hashing and Its Application for Histopathology Image Analysis

    Content-based image retrieval (CBIR)  has attracted considerable  for histopathology image  because it can provide more clinical evidence to support the diagnosis. Hashing is an important tool in CBIR due to...

    **aoshuang Shi, Lin Yang in Deep Learning and Convolutional Neural Net… (2019)

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