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  1. No Access

    Article

    MRE11 lactylation: new insight into DNA damage repair and tumorigenesis

    The increased accumulation of lactate in tumor microenvironment is a characteristic feature of tumorigenesis, which affects various biological processes such as metabolism and immune response. The specific rol...

    Hui Yang, **qin Qian, **aopeng Lu, Wei-Guo Zhu in Genome Instability & Disease (2024)

  2. Article

    Open Access

    Histone methyltransferase GLP epigenetically activates GPCPD1 to sustain cancer cell metastasis and invasion

    Disordered choline metabolism is associated with tumor progression. Glycerophosphocholine phosphodiesterase 1 (GPCPD1) is critical for cleaving glycerophosphocholine (GPC) to produce choline. However, whether ...

    He Wen, Minghui Shu, Jia-Yi Chen, **aofan Li, Qian Zhu… in Genome Instability & Disease (2023)

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  3. Article

    Correction to: TIP60 recruits SUV39H1 to chromatin to maintain heterochromatin genome stability and resist hydrogen peroxide-induced cytotoxicity

    The original version of this article, published on November 6, 2020, contained a mistake.

    Bo Tu, Yantao Bao, Ming Tang, Qian Zhu, **aopeng Lu… in Genome Instability & Disease (2021)

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  4. No Access

    Article

    TIP60 recruits SUV39H1 to chromatin to maintain heterochromatin genome stability and resist hydrogen peroxide-induced cytotoxicity

    Tat interacting protein 60 (TIP60) is a histone acetyltransferase involved in chromatin remodeling and the DNA damage response. However, the role of TIP60 in maintaining genome stability is poorly understood. ...

    Bo Tu, Yantao Bao, Ming Tang, Qian Zhu, **aopeng Lu… in Genome Instability & Disease (2020)