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  1. Article

    Open Access

    LncRNA-Gm9866 promotes liver fibrosis by activating TGFβ/Smad signaling via targeting Fam98b

    The exact mechanism and target molecules of liver fibrosis have remained largely elusive. Here, we investigated the role of long noncoding RNA Gm9866(lncRNA-Gm9866) on liver fibrosis.

    **aomin Liao, **anxian Ruan, Peishan Yao, Dan Yang in Journal of Translational Medicine (2023)

  2. Article

    Open Access

    Remimazolam tosylate's long-term sedative properties in ICU patients on mechanical ventilation: effectiveness and safety

    This study compared remimazolam tosylate with propofol or midazolam to assess its safety and effectiveness for long-term sedation of intensive care unit (ICU) patients requiring mechanical ventilation.

    Zhiyuan Yao, Zhaomin Liao, Guang Li, Lu Wang in European Journal of Medical Research (2023)

  3. Article

    Open Access

    Identification of ZBTB4 as an immunological biomarker that can inhibit the proliferation and invasion of pancreatic cancer

    Zinc finger and BTB domain-containing protein 4 (ZBTB4) belongs to the zinc finger protein family, which has a role in regulating epigenetic inheritance and is associated with cell differentiation and prolifer...

    Zhe Yang, Feiran Chen, Feng Wang, **ubing Chen, Biaolin Zheng, **aomin Liao in BMC Cancer (2023)

  4. Article

    Open Access

    Identification of Timm13 protein translocase of the mitochondrial inner membrane as a potential mediator of liver fibrosis based on bioinformatics and experimental verification

    To explore the association between translocase of the inner mitochondrial membrane 13 (Timm13) and liver fibrosis.

    **aomin Liao, **anxian Ruan, **anbin Wu, Zhejun Deng in Journal of Translational Medicine (2023)

  5. No Access

    Article

    SETD4 in the Proliferation, Migration, Angiogenesis, Myogenic Differentiation and Genomic Methylation of Bone Marrow Mesenchymal Stem Cells

    Epigenetic modification is a crucial mechanism affecting the biological function of stem cells. SETD4 is a histone methyltransferase, and its biological role in bone marrow mesenchymal stem cells (BMSCs) is cu...

    **aomin Liao, Caixia Wu, Zhongming Shao, Shuya Zhang in Stem Cell Reviews and Reports (2021)

  6. Article

    Open Access

    Cancer-secreted exosomal miR-21-5p induces angiogenesis and vascular permeability by targeting KRIT1

    Cancer-secreted exosomes are critical mediators of cancer-host crosstalk. In the present study, we showed the delivery of miR-21-5p from colorectal cancer (CRC) cells to endothelial cells via exosomes increase...

    Qinglian He, Aihua Ye, Weibiao Ye, **aomin Liao, Guoqiang Qin in Cell Death & Disease (2021)

  7. Article

    Open Access

    Short-term stimulation with histone deacetylase inhibitor trichostatin a induces epithelial-mesenchymal transition in nasopharyngeal carcinoma cells without increasing cell invasion ability

    Epithelial-mesenchymal transition (EMT) may be one of the reasons for the failure in some clinical trials regarding histone deacetylase inhibitors (HDACIs)-treated solid tumors. We investigated the effects of ...

    Zhihua Shen, **aomin Liao, Zhongming Shao, Muyin Feng, Jianling Yuan in BMC Cancer (2019)