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Article
Open AccessAn MRI Study of Morphology, Asymmetry, and Sex Differences of Inferior Precentral Sulcus
Numerous studies utilizing magnetic resonance imaging (MRI) have observed sex and interhemispheric disparities in sulcal morphology, which could potentially underpin certain functional disparities in the human...
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Article
Open AccessAngiogenesis modulated by CD93 and its natural ligands IGFBP7 and MMRN2: a new target to facilitate solid tumor therapy by vasculature normalization
The tumor vasculature was different from the normal vasculature in both function and morphology, which caused hypoxia in the tumor microenvironment (TME). Previous anti-angiogenesis therapy had led to a modest...
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Article
Open AccessPoliovirus receptor (PVR)-like protein cosignaling network: new opportunities for cancer immunotherapy
Immune checkpoint molecules, also known as cosignaling molecules, are pivotal cell-surface molecules that control immune cell responses by either promoting (costimulatory molecules) or inhibiting (coinhibitory...
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Chapter
Genetically Encoded Biosensors and Their Applications in the Development of Microbial Cell Factories
The genetically encoded biosensors, which could transform the input of specific metabolic concentrations into output of gene expression levels, have been developed by hacking the sensing and regulatory systems...
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Article
Evaluation and accurate diagnoses of pediatric diseases using artificial intelligence
Artificial intelligence (AI)-based methods have emerged as powerful tools to transform medical care. Although machine learning classifiers (MLCs) have already demonstrated strong performance in image-based dia...
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Chapter
Construction of Microbial Cell Factories by Systems and Synthetic Biotechnology
With the growing concern regarding worsening environment, microbial cell factories have been built for the biorefinery of many products including chemicals, biofuel, nutraceuticals, and pharmaceuticals from re...