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Article
Open AccessThermomiR-377-3p-induced suppression of Cirbp expression is required for effective elimination of cancer cells and cancer stem-like cells by hyperthermia
In recent years, the development of adjunctive therapeutic hyperthermia for cancer therapy has received considerable attention. However, the mechanisms underlying hyperthermia resistance are still poorly under...
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Article
Interoceptive Sensibility Mediates Anxiety Changes Induced by Mindfulness-Based Tai Chi Chuan Movement Intervention
Interoception plays an important role in maintaining body homeostasis, which is closely associated with emotional health and the function of the autonomic nervous system (ANS). Tai Chi Chuan (TCC), as a typica...
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Article
Open AccessDual-energy CT virtual non-calcium: an accurate method for detection of knee osteoarthritis-related edema-like marrow signal intensity
To evaluate the performance of a dual-energy computed tomography (DECT) virtual non-calcium (VNCa) technique in the detection of edema-like marrow signal intensity (ELMSI) in patients with knee joint osteoarth...
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Article
Effects of 8-Week Tai Chi Chuan Practice on Mindfulness Level
Tai Chi Chuan (TCC) is a common mindfulness-based aerobic exercise. However, the evidence on the effects of TCC practice on mindfulness has been controversial. The aim of this study was to explore whether TCC ...
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Article
A density-core-based clustering algorithm with local resultant force
Clustering analysis has been widely used in image segmentation, face recognition, protein identification, intrusion detection, document clustering and so on. Most of the previous clustering algorithms are not ...
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Article
The effects of rainfall regimes and terracing on runoff and erosion in the Three Gorges area, China
Changes in natural rainfall regimes have taken place and are expected to become more pronounced in future decades. These changes are also likely to be accompanied by changes in crop management practices. The m...
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Article
Open AccessEffects of combined application of nitrogen fertilizer and biochar on the nitrification and ammonia oxidizers in an intensive vegetable soil
Soil amended with single biochar or nitrogen (N) fertilizer has frequently been reported to alter soil nitrification process due to its impact on soil properties. However, little is known about the dynamic re...
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Article
Open AccessHypothetical protein Cpn0423 triggers NOD2 activation and contributes to Chlamydia pneumoniae-mediated inflammation
Chlamydia pneumoniae (C. pneumoniae) is pathogenic to humans, by causing pulmonary inflammation or bronchitis in both adolescents and young adults. However, the molecular signals linki...
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Article
Development and characterization of monoclonal antibody against human IL-37b
IL-37 has been described as a natural inhibitor of immune responses. Monoclonal antibody (mAb) against human IL-37b with high affinity and specificity can serve as a molecular probe to detect IL-37 and study I...
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Article
Characterization of stereostructure by X-ray and technology of extracting in combination hydrolysis in situ of acankoreanogenin from leaves of Acanthopanax gracilistylus W. W. Smith
To study the stereostructure by X-ray and the technology of extracting acankoreanogenin from the leaves of Acanthopanax gracilistylus W. W. Smith (AGS), the crystal structure was measured with a Bruker APEX-II ar...
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Article
Questionnaire survey evaluating disease-related knowledge for 149 primary gout patients and 184 doctors in South China
This study aims to investigate the disease-related knowledge of gout patients and doctors in south China and to identify the important targets of education for patients and doctors. A cross-section survey of 1...
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Article
CTLA-4 polymorphisms and systemic lupus erythematosus (SLE): a meta-analysis
The aim of this study was to summarize results on the association of cytotoxic T-lymphocyte antigen-4 (CTLA-4) promoter exon-1 +49 and 1722T/C polymorphism with systemic lupus erythematosus (SLE) susceptibility b...
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Article
Saturated fatty acid induction of endoplasmic reticulum stress and apoptosis in human liver cells via the PERK/ATF4/CHOP signaling pathway
Accumulation of saturated fatty acids in the liver can cause nonalcoholic fatty liver disease (NAFLD). This study investigated saturated fatty acid induction of endoplasmic reticulum (ER) stress and apoptosis ...
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Article
Implementation and evaluation of parallel FFT on Engineering and Scientific Computation Accelerator (ESCA) architecture
The fast Fourier transform (FFT) is a fundamental kernel of many computation-intensive scientific applications. This paper deals with an implementation of the FFT on the accelerator system, a heterogeneous mul...
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Article
Genome-wide association identifies a susceptibility locus for coronary artery disease in the Chinese Han population
Qing Wang and colleagues report a genome-wide association study for coronary artery disease (CAD) in a Chinese Han population. They identify a locus on chromosome 6p24.1 newly associated with CAD.
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Article
Open AccessHMGB1 cytoplasmic translocation in patients with acute liver failure
High-mobility group box 1 (HMGB1) is a late mediator of lethal systemic inflammation. Acute liver failure (ALF) has been shown to trigger systemic inflammation in clinical and animal studies. To evaluate the p...
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Article
Parathyroid hormone-related protein regulates osteoclast inhibitory lectin expression via multiple signaling pathways in osteoblast-like cells
Osteoclast inhibitory lectin (OCIL) is a recently identified inhibitor of osteoclast formation. A variety of osteotropic factors regulate OCIL expression in osteoblastic cells, however, little information is a...
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Article
Over-expression of nm23-H1 in HeLa cells provides cells with higher resistance to oxidative stress possibly due to raising intracellular p53 and GPX1
To determine whether the antitumor factor nm23 is related with antioxidation.
