12 Result(s)
-
Article
Open AccessDetection performance of PCR for Legionella pneumophila in environmental samples: a systematic review and meta-analysis
Legionellosis remains a public health problem. The most common diagnostic method to detect Legionella pneumophila (L. pneumophila) is culture. Polymerase chain reaction (PCR) is a fast and accurate method for thi...
-
Article
Genetic Mutation of SARS-CoV-2 during Consecutive Passages in Permissive Cells
-
Article
Open AccessPDL1 blockage increases fetal resorption and Tfr cells but does not affect Tfh/Tfr ratio and B-cell maturation during allogeneic pregnancy
A successful pregnancy requires sophisticated regulation of uterine microenvironment to guarantee the existence of semi-allogeneic conceptus without immune rejection. T follicular regulatory (Tfr) cells exert ...
-
Article
Presynaptic NMDA receptors control nociceptive transmission at the spinal cord level in neuropathic pain
Chronic neuropathic pain is a debilitating condition that remains challenging to treat. Glutamate N-methyl-d-aspartate receptor (NMDAR) antagonists have been used to treat neuropathic pain, but the exact sites of...
-
Article
Open AccessEIF5A1 promotes trophoblast migration and invasion via ARAF-mediated activation of the integrin/ERK signaling pathway
Trophoblast dysfunction is one mechanism implicated in the etiology of recurrent miscarriage (RM). Regulation of trophoblast function, however, is complex and the mechanisms contributing to dysregulation remai...
-
Article
Open AccessBaicalin administration attenuates hyperglycemia-induced malformation of cardiovascular system
In this study, the effects of Baicalin on the hyperglycemia-induced cardiovascular malformation during embryo development were investigated. Using early chick embryos, an optimal concentration of Baicalin (6 μ...
-
Article
Open AccessNovel chimeric transcript RRM2-c2orf48 promotes metastasis in nasopharyngeal carcinoma
Recently, chimeric transcripts have been found to be associated with the pathogenesis and poor prognosis of malignant tumors. Through our preliminary experiment, a novel chimeric transcript called chimeric tra...
-
Article
Bioactivity, toxicity and detoxification assessment of Dioscorea bulbifera L.: a comprehensive review
Dioscorea bulbifera L. (Chinese: Huangdu, common name: air potato) is a traditional herbal medicine in China, and it is also one of the most widely consumed yam species, especially in Wes...
-
Article
Construction of self-cloning, indigenous wine strains of Saccharomyces cerevisiae with enhanced glycerol and glutathione production
To improve wine taste and flavor stability, a novel indigenous strain of Saccharomyces cerevisiae with enhanced glycerol and glutathione (GSH) production for winemaking was constructed. ALD6 encoding an aldehyde ...
-
Article
Production of CCHF virus-like particle by a baculovirus-insect cell expression system
Crimean-Congo Haemorrhagic Fever Virus (CCHFV) is a tick-born virus of the Nairovirus genus within the Bunyaviridae family, which is widespread and causes high fatality. The nucleocapsid of CCHFV is comprised of ...
-
Article
Role of iNOS-derived reactive nitrogen species and resultant nitrative stress in leukocytes-induced cardiomyocyte apoptosis after myocardial ischemia/reperfusion
Polymorphonuclear leukocyte (PMN) accumulation/activation has been implicated as a primary mechanism underlying MI/R injury. Recent studies have demonstrated that PMNs express inducible nitric oxide synthase (...
-
Article
Study on construction of cDNA libraries from rat normal liver and regeneration liver with smart technique
The aim of the study is to construct cDNA libraries from the normal liver and regeneration liver of rat by SMART (switching mechanism at 5′ end of RNA transcript) technique and analyze their quality. The total...
