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    Article

    Safflower Yellow Inhibits Progression of Hepatocellular Carcinoma by Modulating Immunological Tolerance via FAK Pathway

    To explore the anti-tumor effect of safflower yellow (SY) against hepatocellular carcinoma (HCC) and the underlying potential mechanism.

    Hua-feng Ji, Zi-qiang Yang, Jun-jun Han in Chinese Journal of Integrative Medicine (2024)

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    Article

    Role of dynamic contrast-enhanced MRI in predicting severe acute radiation-induced rectal injury in patients with rectal cancer

    To explore the potential of dynamic contrast-enhanced MRI (DCE-MRI) quantitative parameters in predicting severe acute radiation-induced rectal injury (RRI) in rectal cancer.

    Yan Chen, Li Ding, Zhi-wen Zhang, Xue-han Wu, Yu-tao Que, Yu-ru Ma in European Radiology (2024)

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    Article

    Continuous age- and sex-specific reference ranges of liver enzymes in Chinese children and application in pediatric non-alcoholic fatty liver disease

    Alanine aminotransferase (ALT) is widely used to screen patients with hepatic diseases. However, the current reference ranges (< 50 U/L) were developed by laboratories and have not been validated in population...

    Zhao-Yuan Wu, Si-Wei Chi, Liu-Jian Ouyang, **ao-Qin Xu in World Journal of Pediatrics (2024)

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    Reference Work Entry In depth

    International Consensus on Natural Orifice Specimen Extraction Surgery (NOSES) for Gastric Cancer (2019)

    At present, natural orifice specimen extraction surgery (NOSES) has attracted more and more attention worldwide, because of its great advantages including minimal cutaneous trauma and postoperative pain, fast ...

    Xu Guan, Zheng Liu, Amjad Parvaiz in Natural Orifice Specimen Extraction Surgery (2023)

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    Article

    Two effective clinical prediction models to screen for obstructive sleep apnoea based on body mass index and other parameters

    The diagnosis of obstructive sleep apnea (OSA) relies on polysomnography which is time-consuming and expensive. We therefore aimed to develop two simple, non-invasive models to screen adults for OSA.

    Guo-qiang Song, De-lu Wang, Hua-man Wu, Qiao-jun Wang, Fei Han in Sleep and Breathing (2022)

  6. Article

    Open Access

    Chinese patent herbal medicine Huaiqihuang for Henoch-Schonlein purpura nephritis in children: a systematic review of randomized controlled trials

    Henoch-Schönlein purpura nephritis (HSPN) is listed as the most common secondary glomerular diseases among children. Approximately 15 to 20% of children eventually could develop into chronic renal failure. Chi...

    Xue Xue, Xue-han Liu, Chun-li Lu, in BMC Complementary Medicine and Therapies (2021)

  7. Article

    Open Access

    Detection of an anti-angina therapeutic module in the effective population treated by a multi-target drug Danhong injection: a randomized trial

    It’s a challenge for detecting the therapeutic targets of a polypharmacological drug from variations in the responsed networks in the differentiated populations with complex diseases, as stable coronary heart ...

    Jun Liu, Dan-Dan Li, Wei Dong, Yu-Qi Liu in Signal Transduction and Targeted Therapy (2021)

  8. Article

    Open Access

    Risk Factors for Adverse Pregnancy Outcomes among Zhuang Ethnic Pregnant Women: A Cohort Study in Guangxi, China

    Risk factors for adverse pregnancy outcomes among Zhuang ethnic pregnant women are unclear. This study analyzed the incidence and risk factors related to preterm birth (PB), low birth weight (LBW) and macrosom...

    Bao-ying Feng, Yang Peng, Jun Liang, Li Wu, Qun-jiao Jiang in Current Medical Science (2021)

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    Article

    The Modified Rectangle Flap Epicanthoplasty: A Novel and Individualized Design

    The epicanthal fold is ordinary in the eyelids of Asians, and the aesthetic appearance of eyelid surgery could be reduced and undermined; thus, medial epicanthoplasty is commonly performed to eliminate the eff...

    Zhe Cao, Yong-Qiang Guo, Shen-**ng Tan, Chang-Ying Niu in Aesthetic Plastic Surgery (2021)

  10. Article

    Open Access

    Hippocampal µ-opioid receptors on GABAergic neurons mediate stress-induced impairment of memory retrieval

    Stressful life events induce abnormalities in emotional and cognitive behaviour. The endogenous opioid system plays an essential role in stress adaptation and co** strategies. In particular, the µ-opioid rec...

    Mei-Mei Shi, Ka-Min Fan, Yan-Ning Qiao, **-Hui Xu, Li-Juan Qiu in Molecular Psychiatry (2020)

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    Article

    Effects of intraarticular 32P colloid in the treatment of hemophilic synovitis of the knee

    Background: Chronic synovitis is a consequence of recurrent intraarticular hemorrhage in patients with hemophilia. Eventually, synovitis leads to degeneration of the articular cartilage, with serious consequences...

    Wen-Qiang Zhang, Shao-Qin Han, Zhen Yuan, Ye-Teng He in Indian Journal of Orthopaedics (2016)

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    Article

    Glucocorticoid receptor agonist dexamethasone attenuates renal ischemia/reperfusion injury by up-regulating eNOS/iNOS

    The aim of this study was to determine the effect of dexamethasone (DEX) on renal ischemia/reperfusion injury (IRI). C57BL/6 mice were randomly divided into Sham group, IRI group and DEX group. The mice in IRI...

    Jiong Zhang 张 炯, Jun-hua Li **俊华, Le Wang 王 艻 in Journal of Huazhong University of Science … (2014)

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    Article

    Identification of novel serological tumor markers for human prostate cancer using integrative transcriptome and proteome analysis

    The aim of this study was to identify novel serological tumor markers for human prostate cancer (PCa). We compared the gene expression profile of PCa tissues to adjacent benign tissues of prostate using gene e...

    Zhao-dong Han, Yan-qiong Zhang, Hui-chan He, Qi-shan Dai, Guo-qiang Qin in Medical Oncology (2012)

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    Article

    Extracellular matrix metalloproteinase inducer: a novel poor prognostic marker for human seminomas

    Extracellular matrix metalloproteinase inducer (EMMPRIN) is a glycosylated member of the immunoglobulin superfamily whose function in human seminomas is unknown. We have recently determined that EMMPRIN posses...

    Xue-Cheng Bi, Jiu-Min Liu, Hui-Chan He, Yong-Kang Ye in Clinical and Translational Oncology (2012)

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    Article

    mTOR Signaling Pathway Is a Target for the Treatment of Colorectal Cancer

    mTOR signaling has been suggested to be an important factor involved in tumorigenesis, but its role in human colorectal cancer (CRC) has not been completely elucidated. Herein, the purpose of this study was to...

    Yan-Jie Zhang PhD, MD, Qiang Dai MD, Dan-Feng Sun PhD, MD in Annals of Surgical Oncology (2009)