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  1. Article

    Open Access

    Downregulation of GPX8 in hepatocellular carcinoma: impact on tumor stemness and migration

    GPX8, which is found in the endoplasmic reticulum lumen, is a member of the Glutathione Peroxidases (GPXs) family. Its role in hepatocellular carcinoma (HCC) is unknown.

    Chen-Yang Tao, **ao-Ling Wu, Shu-Shu Song, Zheng Tang, Yu-Fu Zhou in Cellular Oncology (2024)

  2. Article

    Open Access

    Online decision tools for personalized survival prediction and treatment optimization in elderly patients with lung squamous cell carcinoma: a retrospective cohort study

    Despite major advances in cancer therapeutics, the therapeutic options of Lung Squamous Cell Carcinoma (LSCC)-specific remain limited. Furthermore, the current staging system is imperfect for defining a progno...

    Chen-ye Shao, **g Luo, Sheng Ju, Chu-ling Li, Cheng Ding, Jun Chen in BMC Cancer (2023)

  3. Article

    Open Access

    Efficacy and safety of combined targeted therapy and immunotherapy versus targeted monotherapy in unresectable hepatocellular carcinoma: a systematic review and meta-analysis

    Cancer therapy has evolved from non-specific cytotoxic agents to a selective, mechanism-based approach that includes targeted agents and immunotherapy. Although the response to targeted therapies for unresecta...

    Teng-Kai Yang, Ya-Fang Yu, Chiao-Ling Tsai, Hsing-Ju Li, Po-Sheng Yang in BMC Cancer (2022)

  4. Article

    Open Access

    NR2F1 contributes to cancer cell dormancy, invasion and metastasis of salivary adenoid cystic carcinoma by activating CXCL12/CXCR4 pathway

    Salivary adenoid cystic carcinoma (SACC) can recur after removal of the primary tumor and treatment, where they can keep no clinical symptoms and dormant state for 10–15 years. NR2F1 has been demonstrated to r...

    **ao-lei Gao, Min Zheng, Hao-fan Wang, Lu-ling Dai, **ang-hua Yu, **ao Yang in BMC Cancer (2019)

  5. Article

    Open Access

    The safety and efficacy of transarterial chemoembolization combined with sorafenib and sorafenib mono-therapy in patients with BCLC stage B/C hepatocellular carcinoma

    Sorafenib and transarterial chemoembolization (TACE) are recommended therapies for advanced hepatocellular carcinoma (HCC), but their combined efficacy remains unclear.

    Fei-**ang Wu, Jie Chen, Tao Bai, Shao-Liang Zhu, Tian-Bo Yang, Lu-Nan Qi in BMC Cancer (2017)

  6. No Access

    Article

    Novel patterns of p53 abnormality in breast cancer from Taiwan: experience from a low-incidence area

    Among 114 breast cancers in Taiwan, the prevalence of p53 mutation (22.8%) and p53 accumulation (38.3%) was similar to that in high-incidence areas. However, novel patterns of p53 abnormalities, including uniq...

    M Ann Ann Lou, Su-Ling Tseng, Shu-Fen Chang, Chung-Tai Yue in British Journal of Cancer (1997)