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  1. Article

    Open Access

    Investigation of Metabolic and Inflammatory Disorder in the Aging FGF21 Knockout Mouse

    Aging is a physiological condition accomplished with persistent low-grade inflammation and metabolic disorders. FGF21 has been reported to act as a potent longevity determinant, involving inflammatory response...

    Lu-Qiong Cai, **u-Chun Li, Yang-Yue Wang, Yu-**n Chen, **a-Yan Zhu in Inflammation (2024)

  2. No Access

    Article

    124I-labeled anti-CD147 antibody for noninvasive detection of CD147-positive pan-cancers: construction and preclinical studies

    Extracellular matrix metalloproteinase inducer CD147 is a glycoprotein on the cell surface. There is minimal expression of CD147 in normal epithelial and fetal tissues, but it is highly expressed in a number o...

    **ao-kun Ma, Te-li Liu, Ya-nan Ren, **ao-pan Ma, Yuan Yao in Acta Pharmacologica Sinica (2024)

  3. No Access

    Article

    Prognostic value of serum HIF-1α change following transarterial chemoembolization in hepatocellular carcinoma

    Transarterial chemoembolization (TACE) induces a change in serum HIF-1α level in patients with hepatocellular carcinoma (HCC). This study investigated the prognostic value of change in serum HIF-1α following T...

    Zhi-Huan Lin, Jun-Rong Jiang, **ao-Kun Ma, Jie Chen in Clinical and Experimental Medicine (2021)

  4. Article

    Open Access

    Preparation and structural determination of four metabolites of senkyunolide I in rats using ultra performance liquid chromatography/quadrupole-time-of-flight tandem mass and nuclear magnetic resonance spectra

    Senkyunolide I (SEI) is one of the most important bioactive phthalides of Ligusticum chuanxiong Hort. (Umbelliferae), a Traditional Chinese Medicine. Our previous studies suggested that it might be developed as a...

    Qiang Ma, Cong Ma, Fei Wu, Yao-kun **ong in BMC Complementary and Alternative Medicine (2016)

  5. No Access

    Article

    Low expression of Beclin 1 and elevated expression of HIF-1α refine distant metastasis risk and predict poor prognosis of ER-positive, HER2-negative breast cancer

    Even though ER-positive, HER2-negative breast tumors represent a subset of breast cancers with a better clinical outcome, approximately 12.7 % of patients in this subgroup ultimately develop cancer-related mor...

    Min Dong, **ang-bo Wan, Zhong Yu Yuan, Li Wei, **n Juan Fan in Medical Oncology (2013)

  6. Article

    In vitro characteristics of poly(lactic-co-glycolic acid) microspheres incorporating gelatin particles loading basic fibroblast growth factor

    To construct a sustained drug release system for basic fibroblast growth factor (bFGF). With this special system, bFGF can be used to repair an injured peripheral nerve, injured spinal cord, or as a carrier fo...

    Shao-hong Li, Shao-xi Cai, Bing Liu, Kai-wang Ma in Acta Pharmacologica Sinica (2006)