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  1. Article

    Open Access

    Anti-metabolic agent pegaspargase plus PD-1 antibody sintilimab for first-line treatment in advanced natural killer T cell lymphoma

    Natural killer T cell lymphoma (NKTCL) is highly aggressive, with advanced stage patients poorly responding to intensive chemotherapy. To explore effective and safe treatment for newly diagnosed advanced stage...

    Jie **ong, Shu Cheng, **ao Gao, Shan-He Yu in Signal Transduction and Targeted Therapy (2024)

  2. Article

    Open Access

    Quality of life in young patients with acute type a aortic dissection in China: comparison with Marfan syndrome and non-Marfan syndrome

    There is a paucity of Chinese studies evaluating the quality of life (QoL) in young acute type A aortic dissection (AAAD) patients with Marfan syndrome.

    **n-fan Lin, Lin-feng **e, Zhao-feng Zhang, Jian He in BMC Cardiovascular Disorders (2024)

  3. No Access

    Article

    Real-world treatment outcome with protease inhibitor direct-acting antiviral in advanced hepatitis C cirrhosis: a REAL-C study

    Current guidelines discourage the use of direct-acting antiviral (DAA) containing protease-inhibitor (PI) in advanced HCV cirrhosis. We aimed to compare the real-world tolerability of PI vs. non-PI DAA regimen...

    Yu Jun Wong, Sally Tran, Chung-Feng Huang, Yao-Chun Hsu in Hepatology International (2023)

  4. Article

    Effectiveness and safety of 8-week glecaprevir/pibrentasvir in HCV treatment-naïve patients with compensated cirrhosis: real-world experience from Taiwan nationwide HCV registry

    Large-scale real-world data of the 8-week glecaprevir/pibrentasvir (GLE/PIB) therapy for treatment-naïve patients of chronic hepatitis C virus (HCV) infection with compensated cirrhosis is scarce.

    Te-Sheng Chang, Chung-Feng Huang, Hsing-Tao Kuo, Ching-Chu Lo in Hepatology International (2023)

  5. Article

    Open Access

    Continuous dynamic identification of key genes and molecular signaling pathways of periosteum in guided bone self-generation in swine model

    Guided bone self-generation with periosteum-preserved has successfully regenerated mandibular, temporomandibular and interphalangeal joint. The aim of this study was to investigate the dynamic changes of gene ...

    Bao-Fu Yu, Zi Wang, **ao-Xue Chen, Qi Zeng in Journal of Orthopaedic Surgery and Research (2023)

  6. Article

    Open Access

    Impact of frailty status on clinical and functional outcomes after concomitant valve replacement and bipolar radiofrequency ablation in patients aged 65 years and older

    To evaluate the prognostic value of frailty in older recipients of concomitant valve replacement (VR) and bipolar radiofrequency ablation (BRFA), we examined whether clinical and functional outcomes differed b...

    Zhi-qin Lin, **u-jun Chen, **ao-fu Dai, Liang-wan Chen in Journal of Cardiothoracic Surgery (2022)

  7. Article

    Open Access

    Do obese patients benefit from isolated aortic valve replacement through a partial upper sternotomy?

    Controversial opinions exist for aortic valve replacement (AVR) through partial upper sternotomy in obese patients. Moreover, this study sought to investigate the potential clinical advantage of partial upper ...

    **an-Biao **e, **ao-Fu Dai, Zhi-Huang Qiu in Journal of Cardiothoracic Surgery (2022)

  8. Article

    Open Access

    Dynamic transcriptome analysis of NFAT family in guided bone regeneration with occlusive periosteum in swine model

    To investigate the dynamic expression of NFAT family of periosteum in guided bone regeneration process.

    Bao-Fu Yu, Ning Yin, Zi Wang, **ao-Xue Chen in Journal of Orthopaedic Surgery and Research (2022)

  9. Article

    Open Access

    Impact of minimally invasive mitral valve surgery on sexual dysfunction in male patients

    Sexual dysfunction after cardiac surgery can seriously affect patients’ quality of life, but the impact of cardiac surgery on sexual function has long been neglected. Compared with conventional cardiac surgery...

    Liang-liang Yan, Mi-rong Tang, **ao-fu Dai in Journal of Cardiothoracic Surgery (2022)

  10. Article

    Open Access

    Detection of an anti-angina therapeutic module in the effective population treated by a multi-target drug Danhong injection: a randomized trial

    It’s a challenge for detecting the therapeutic targets of a polypharmacological drug from variations in the responsed networks in the differentiated populations with complex diseases, as stable coronary heart ...

    Jun Liu, Dan-Dan Li, Wei Dong, Yu-Qi Liu in Signal Transduction and Targeted Therapy (2021)

  11. Article

    Open Access

    Open Seldinger-guided peripheral femoro-femoral cannulation technique for totally endoscopic cardiac surgery

    The cannulation technique used in totally endoscopic cardiac surgery has a significant impact on the overall prognosis of patients. However, there are no large cohort studies to discuss it. Here we report on o...

    Yi Chen, Liang-wan Chen, **ao-fu Dai, Xue-shan Huang in Journal of Cardiothoracic Surgery (2021)

  12. Article

    Open Access

    Totally endoscopic mitral valve surgery: early experience in 188 patients

    Totally endoscopic technique has been widely used in cardiac surgery, and minimally invasive totally endoscopic mitral valve surgery has been developed as an alternative to median sternotomy for many patients ...

    Yi Chen, Ling-chen Huang, Dao-zhong Chen in Journal of Cardiothoracic Surgery (2021)

  13. Article

    Open Access

    Peripheral vascular complications following totally endoscopic cardiac surgery

    Clinical application of minimally invasive cardiac surgery has increased annually. Cardiopulmonary bypass is established by peripheral cannulation during minimally invasive cardiac surgery. The methodology of ...

    Ling-chen Huang, Qi-chen Xu, Dao-zhong Chen in Journal of Cardiothoracic Surgery (2021)

  14. Article

    Open Access

    Combined femoral and axillary perfusion strategy for Stanford type a aortic dissection repair

    The optimal cannulation strategy in surgery for Stanford type A aortic dissection is critical to patient survival but remains controversial. Different cannulation strategies have their own advantages and drawb...

    Ling-chen Huang, Qi-chen Xu, Dao-zhong Chen in Journal of Cardiothoracic Surgery (2020)

  15. Article

    Open Access

    The use of the Scar Cosmesis Assessment and rating scale to evaluate the cosmetic outcomes of totally thoracoscopic cardiac surgery

    Conventional median sternotomy is widely used in cardiac surgery, while thoracoscopic cardiac surgery, which is considered to have aesthetic advantages, is being performed increasingly more often in China beca...

    Ling-chen Huang, Dao-zhong Chen, Liang-wan Chen in Journal of Cardiothoracic Surgery (2020)

  16. Article

    Open Access

    Health-related quality of life following minimally invasive totally endoscopic mitral valve surgery

    To compare the impact of two different types of mitral valve surgery on health-related quality of life, we conducted a retrospective study comparing modified totally endoscopic mitral valve surgery with median...

    Ling-chen Huang, Dao-zhong Chen, Liang-wan Chen in Journal of Cardiothoracic Surgery (2020)

  17. Article

    Open Access

    Thioredoxin H (TrxH) contributes to adversity adaptation and pathogenicity of Edwardsiella piscicida

    Thioredoxins (Trxs) play an important role in defending against oxidative stress and kee** disulfide bonding correct to maintain protein function. Edwardsiella piscicida, a severe fish pathogen, has been shown ...

    Bi-ying Wang, Hui-qin Huang, Shuang Li, ** Tang, Hao-fu Dai in Veterinary Research (2019)

  18. Article

    Open Access

    A modified multiple branched graft for thoracoabdominal aortic aneurysm repair

    To reduce some problems of traditional graft, we devise a modified multiple branched graft for repair of Crawford extent II and III thoracoabdominal aortic aneurysm (TAAA).

    Liang-Wan Chen, **-Jie Wu, Hua Cao, **ao-Fu Dai in Journal of Cardiothoracic Surgery (2017)

  19. Article

    Open Access

    31st Annual Meeting and Associated Programs of the Society for Immunotherapy of Cancer (SITC 2016): part two

    Casey Ager, Matthew Reilley, Courtney Nicholas in Journal for ImmunoTherapy of Cancer (2016)

  20. Article

    Open Access

    31st Annual Meeting and Associated Programs of the Society for Immunotherapy of Cancer (SITC 2016): part one

    Andreas Lundqvist, Vincent van Hoef, **aonan Zhang in Journal for ImmunoTherapy of Cancer (2016)

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