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Article
Metabolic obesity phenotypes and all-cause mortality among the Chinese oldest-old population: a prospective cohort study
The obesity paradox has been reported among older adults. However, whether the favorable effect of obesity is dependent on metabolic status remains largely unknown. We aimed to explore the association of metab...
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Article
Open AccessChanges of Mycobacterium tuberculosis specific antigen-stimulated CD27−CD38+IFN-γ+CD4+ T cells before and after anti-tuberculosis treatment
The aim of the study was to investigate whether the expression of CD27−CD38+ in interferon (IFN)-γ+CD4+ T cells stimulated by the specific antigen early secreted antigenic target-6 (ESAT-6)/culture filter protein...
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Article
Open AccessConsensus for criteria of running a pediatric inflammatory bowel disease center using a modified Delphi approach
Good quality of care for inflammatory bowel disease (IBD) depends on high-standard management and facility in the IBD center. Yet, there are no clear measures or criteria for evaluating pediatric IBD (PIBD) ce...
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Article
Distinct Lymphocyte Immunophenoty** and Quantitative Anti-Interferon Gamma Autoantibodies in Taiwanese HIV-Negative Patients with Non-Tuberculous Mycobacterial Infections
The presence of anti-interferon-γ autoantibodies (AutoAbs-IFN-γ) is not rare in patients suffering from persistent non-tuberculous mycobacterial (NTM) infections that are characteristic of adult-onset immunode...
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Open AccessA predictive model of response to metoprolol in children and adolescents with postural tachycardia syndrome
The present work was designed to explore whether electrocardiogram (ECG) index-based models could predict the effectiveness of metoprolol therapy in pediatric patients with postural tachycardia syndrome (POTS).
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Article
Analgesic effect of electroacupuncture on bone cancer pain in rat model: the role of peripheral P2X3 receptor
Upregulation of P2X3 receptor (P2X3R) has been strongly implicated in nociceptive signaling including bone cancer pain (BCP). The present study, using rat bone cancer model, aimed to explore the role of P2X3R ...
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Article
Effect modification by aging on the associations of nicotine exposure with cognitive impairment among Chinese elderly
Active and passive exposure to tobacco smoke may increase risk of cognitive decline. However, effects of enhanced the aging process on the association of urinary nicotine metabolites with cognitive impairment ...
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Article
Open AccessExpert consensus on the monitoring and treatment of sepsis-induced immunosuppression
Emerged evidence has indicated that immunosuppression is involved in the occurrence and development of sepsis. To provide clinical practice recommendations on the immune function in sepsis, an expert consensus...
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Article
Simple chiral sulfinyl imine–thioether ligands for Pd-catalyzed allylic alkylation
A set of chiral sulfinyl imine–thioether ligands are prepared via dehydration condensation of substituted benzaldehyde and chiral sulfinamide. The activity of these ligands in Pd-catalyzed asymmetric allylic a...
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Article
Electroacupuncture Attenuates Ischemic Brain Injury and Cellular Apoptosis via Mitochondrial Translocation of Cofilin
To investigate the potential mechanisms of electroacupuncture (EA) to prevent ischemic stroke.
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Article
Open AccessHerbal therapy for ameliorating nonalcoholic fatty liver disease via rebuilding the intestinal microecology
The worldwide prevalence of nonalcoholic fatty liver disease (NAFLD) is increasing, and this metabolic disorder has been recognized as a severe threat to human health. A variety of chemical drugs have been app...
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Article
Open AccessMeta-omics characteristics of intestinal microbiota associated to HBeAg seroconversion induced by oral antiviral therapy
Tenofovir and entecavir are currently designated as the preferred oral antiviral drugs for chronic hepatitis B. However, only less than 40% of patients can achieve HBeAg seroconversion. We aim at investigating...
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Article
Discovery of oscillations above 200 keV in a black hole X-ray binary with Insight-HXMT
Low-frequency quasiperiodic oscillations (LFQPOs) are commonly found in black hole X-ray binaries, and their origin is still under debate. The properties of LFQPOs at high energies (above 30 keV) are closely r...
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Article
Open AccessPsychological impact of COVID-19 on medical care workers in China
Medical care workers experienced unprecedented levels of workload and pressure since the outbreak of coronavirus disease 2019 (COVID-19). Little is known about its exact impact on medical care workers and rela...
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Article
VHL-HIF-2α axis-induced SMYD3 upregulation drives renal cell carcinoma progression via direct trans-activation of EGFR
It has been well established that the von Hippel-Lindau/hypoxia-inducible factor α (VHL-HIFα) axis and epidermal growth factor receptor (EGFR) signaling pathway play a critical role in the pathogenesis and pro...
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Article
Open AccessPredictors of five-year relapse rates of youths with substance abuse who underwent a family-oriented therapy program
Substance abuse among young people has become a serious public health problem for years. The risk of relapse among illicit drug use is essential for develo** adequate substance reuse prevention policies. The...
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Article
Fuzzy Guaranteed Cost \(H\infty\) Control of Uncertain Nonlinear Fuzzy Vehicle Active Suspension with Random Actuator Delay
This paper focuses on the fuzzy guaranteed cost \(H\infty\) ...
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Article
Ginkgo biloba extracts prevent aortic rupture in angiotensin II-infused hypercholesterolemic mice
Abdominal aortic aneurysms (AAAs) are a chronic vascular disease characterized by pathological luminal dilation. Aortic rupture is the fatal consequence of AAAs. Ginkgo biloba extracts (GBEs), a natural herb extr...
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Article
Study on the Sintering Mechanism of Y2O3 on CaZrO3 Ceramic
In order to research the sintering mechanism of Y2O3 on CaZrO3, CaZrO3 was synthesized by solid reaction using analytical ZrO2 and CaCO3 as raw materials and Y2O3 as additive. The liner change rate, the relative ...
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Article
Enhancing parameter estimation precision by non-Hermitian operator process
Recently, Zhong et al. (Phys Rev A 87:022337, 2013) investigated the dynamics of quantum Fisher information (QFI) in the presence of decoherence. We here reform their results and propose two schemes to enhance an...