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    Chapter and Conference Paper

    A Unified Deep Biological Sequence Representation Learning with Pretrained Encoder-Decoder Model

    Machine learning methods are increasingly being applied to model and predict biomolecular interactions, while efficient feature representation plays a vital role. To this end, a unified biological sequence dee...

    Hai-Cheng Yi, Zhu-Hong You, **ao-Rui Su in Intelligent Computing Theories and Applica… (2020)

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    Chapter and Conference Paper

    A Novel Computational Approach for Predicting Drug-Target Interactions via Network Representation Learning

    Detection of drug-target interactions (DTIs) has a beneficial effect on both pathogenesis and drugs discovery. Although a huge number of DTIs have been generated recently, the number of known interactions is s...

    **ao-Rui Su, Zhu-Hong You, Ji-Ren Zhou in Intelligent Computing Theories and Applica… (2020)

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    Chapter and Conference Paper

    Protein-Protein Interaction Prediction by Integrating Sequence Information and Heterogeneous Network Representation

    Protein-protein interaction (PPI) plays an important role in regulating cells and signals. PPI deregulation will lead to many diseases, including pernicious anemia or cancer. Despite the ongoing efforts of the...

    **ao-Rui Su, Zhu-Hong You, Zhan-Heng Chen in Intelligent Computing Theories and Applica… (2021)

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    Chapter and Conference Paper

    Detection of Drug-Drug Interactions Through Knowledge Graph Integrating Multi-attention with Capsule Network

    Drug-drug interaction (DDI) prediction is a challenging problem in drug development and disease treatment. Current computational studies mainly solve this problem by designing features and extracting features ...

    **ao-Rui Su, Zhu-Hong You, Hai-Cheng Yi in Intelligent Computing Theories and Applica… (2021)

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    Chapter and Conference Paper

    Predicting miRNA-Disease Associations via a New MeSH Headings Representation of Diseases and eXtreme Gradient Boosting

    Taking into account the intrinsic high cost and time-consuming in traditional Vitro studies, a computational approach that can enable researchers to easily predict the potential miRNA-disease associations is i...

    Bo-Ya Ji, Zhu-Hong You, Lei Wang, Leon Wong in Intelligent Computing Theories and Applica… (2021)