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Article
Open AccessUnique physiological and pathogenic features of Leptospira interrogans revealed by whole-genome sequencing
Leptospirosis is a widely spread disease of global concern. Infection causes flu-like episodes with frequent severe renal and hepatic damage, such as haemorrhage and jaundice. In more severe cases, massive pul...
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Article
Identification of intermediate and product from methemoglobin-catalyzed oxidation of o-phenylenediamine in two-phase aqueous—organic system
Methemoglobin (metHb) was used as a mimetic enzyme for peroxidase to catalyze the oxidation reaction of o-phenylenediamine (OPDA) with H2O2 functioning as an oxidant. A reaction intermediate was obtained in two-p...
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Article
Identification of intermediate and product from methemoglobin-catalyzed oxidation of o-phenylenediamine in two-phase aqueous—organic system
Methemoglobin (metHb) was used as a mimetic enzyme for peroxidase to catalyze the oxidation reaction of o-phenylenediamine (OPDA) with H2O2 functioning as an oxidant. A reaction intermediate was obtained in two-p...
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Article
Open AccessRecent advances in basic neurosciences and brain disease: from synapses to behavior
Understanding basic neuronal mechanisms hold the hope for future treatment of brain disease. The 1st international conference on synapse, memory, drug addiction and pain was held in beautiful downtown Toronto,...
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Article
Fabrication of a white organic light-emitting device with single liq:rubrence luminescent layer
A kind of white OLED with single luminescent layer was designed, in which rubrene was doped in Liq. The structure of the devices is ITO/PVK:TPD/Liq: Rubrene/Alq3/Al. The brightness of the devices comes to 3120...
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Article
Microbial production of meso-2,3-butanediol by metabolically engineered Escherichia coli under low oxygen condition
A metabolically engineered Escherichia coli has been constructed for the production of meso-2,3-butanediol (2,3-BD) under low oxygen condition. Genes responsible for 2,3-BD formation from pyruvate were assembled ...
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Article
Production of polyhydroxyalkanoates by Escherichia coli mutants with defected mixed acid fermentation pathways
A series of Escherichia coli BW25113 mutants with reduced mixed acid fermentation were constructed. Genes ackA-pta, poxB, ldhA, adhE, and pflB encoding acetate kinase, phosphate acetyltransferase, pyruvate oxidas...
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Article
Genome-wide association study of esophageal squamous cell carcinoma in Chinese subjects identifies a susceptibility locus at PLCE1
Li Dong Wang and colleagues report a genome wide association study for esophageal squamous cell carcinoma in the Chinese population. They identify two risk loci at PLCE1 and C20orf54.
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Chapter and Conference Paper
Residual Belief Propagation for Topic Modeling
Fast convergence speed is a desired property for training topic models such as latent Dirichlet allocation (LDA), especially in online and parallel topic modeling algorithms for big data sets. In this paper, w...
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Article
Molecular characterization of two recombinant potato virus Y isolates from China
Isolates of potato virus Y (PVY) have been divided into several strains. We determined the genomic sequences of PVY isolates AQ4 and FZ10 from tobacco in China. AQ4 and FZ10 had genome of 9700 and 9698 nucleot...
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Article
Higher-level production of ascomycin (FK520) by Streptomyces hygroscopicus var. ascomyceticus irradiated by femtosecond laser
Femtosecond laser irradiation technology was employed for the first time to improve the ascomycin (FK520) yield of Streptomyces hygroscopicus var. ascomyceticus NT2-11, which is an N-methyl-N-nitro-N-nitrosoguani...
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Article
Incidence of brain injuries in premature infants with gestational age ≤34 weeks in ten urban hospitals in China
There is a large number (1.5 million per year) of premature births in China. It is necessary to obtain the authentic incidences of intraventricular hemorrhage (IVH) and periventricular leukomalacia (PVL), the ...
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Article
Genomic study of polyhydroxyalkanoates producing Aeromonas hydrophila 4AK4
The complete genome of Gram-negative Aeromonas hydrophila 4AK4 that has been used for industrial production of poly(3-hydroxybutyrate-co-3-hydroxyhexanoate) was sequenced and annotated. Its chromosome is 4,527,99...
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Article
Biodegradation of Crude Oil by a Newly Isolated Strain Rhodococcus sp. JZX-01
A highly efficient oil-degrading bacteria JZX-01 was isolated from the oil-contaminated soil of the seacoast near the Boxi Offshore Oil Field of China. Morphological, physiological, and 16S rDNA gene sequence ...
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Article
Corrigendum: Genome-wide association study of esophageal squamous cell carcinoma in Chinese subjects identifies susceptibility loci at PLCE1 and C20orf54
Nat. Genet. 42, 759–763 (2010); published online 22 August 2010; corrected after print 27 August 2014 In contrast to the version of this article initially published, the authors now find no evidence to support...
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Article
Open AccessIntegrated photonics with programmable non-volatile memory
Silicon photonics integrated circuits (Si-PIC) with well-established active and passive building elements are progressing towards large-scale commercialization in optical communications and high speed optical ...
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Article
Fungal diversity notes 253–366: taxonomic and phylogenetic contributions to fungal taxa
Notes on 113 fungal taxa are compiled in this paper, including 11 new genera, 89 new species, one new subspecies, three new combinations and seven reference specimens. A wide geographic and taxonomic range of ...
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Article
Ascending aortic distensibility and target organ damage in primary hypertension without diabetes
To investigate the relationship between ascending aortic distensibility (AAD) and hypertensive target organ damage (TOD) and its potential value in prediction. One hundred and sixty seven primary hypertension ...
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Article
Variation of the uniaxial tensile behavior of ultrafine-grained pure aluminum after cyclic pre-deformation
To explore the influence of cyclic pre-deformation on the mechanical behavior of ultrafine-grained (UFG) materials with a high stacking fault energy (SFE), UFG Al processed by equal-channel angular pressing (E...
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Article
Open AccessEvaluation of the HOXA11 level in patients with lung squamous cancer and insights into potential molecular pathways via bioinformatics analysis
This study was carried out to discover the underlying role that HOXA11 plays in lung squamous cancer (LUSC) and uncover the potential corresponding molecular mechanisms and functions of HOXA11-related genes.
