Skip to main content

and
  1. Article

    Open Access

    Effect of BIM expression on the prognostic value of PD-L1 in advanced non-small cell lung cancer patients treated with EGFR-TKIs

    The role of Programmed Cell Death Ligand 1 (PD-L1) expression in predicting epidermal growth factor receptor tyrosine kinase inhibitor (EGFR-TKIs) efficacy remains controversial. Recent studies have highlighte...

    Chang-Yao Chu, Chien-Yu Lin, Chien-Chung Lin, Chien-Feng Li in Scientific Reports (2023)

  2. Article

    Open Access

    The surgical resection of the primary tumor increases survival in patients with EGFR-mutant advanced non-small cell lung cancer: a tertiary center cohort study

    Tumor resection could increase treatment efficacy of epidermal growth factor receptor (EGFR)-tyrosine kinase inhibitors (TKI) in patients with advanced EGFR-mutant non-small cell lung cancer (NSCLC). This stud...

    Ying-Yuan Chen, Po-Lan Su, Wei-Li Huang, Chao-Chun Chang, Yi-Ting Yen in Scientific Reports (2022)

  3. Article

    Open Access

    The interrelationships between neuronal viability, synaptic integrity, microglial responses, and amyloid-beta formation in an in vitro neurotrauma model

    The interrelationships between neuronal viability, synaptic integrity, and microglial responses remain in infancy. In dealing with the question, we induced a stretch injury to evaluate the mechanical effects o...

    Lan-Wan Wang, Hung-Jung Lin, Chien-Ming Chao, Mao-Tsun Lin in Scientific Reports (2022)

  4. Article

    Open Access

    Comparative transcriptome and WGCNA reveal key genes involved in lignocellulose degradation in Sarcomyxa edulis

    The developmental transcriptomes of Sarcomyxa edulis were assessed to explore the molecular mechanisms underlying lignocellulose degradation. Six stages were analyzed, spanning the entire developmental process: g...

    Chao Duan, Feng-hua Tian, Lan Yao, Jian-Hua Lv, Chuan-Wen Jia in Scientific Reports (2022)

  5. Article

    Open Access

    WAKE-mediated modulation of cVA perception via a hierarchical neuro-endocrine axis in Drosophila male-male courtship behaviour

    The nervous and endocrine systems coordinate with each other to closely influence physiological and behavioural responses in animals. Here we show that WAKE (encoded by wide awake, also known as wake) modulates m...

    Shiu-Ling Chen, Bo-Ting Liu, Wang-Pao Lee, Sin-Bo Liao in Nature Communications (2022)

  6. Article

    Open Access

    The impact of driver mutation on the treatment outcome of early-stage lung cancer patients receiving neoadjuvant immunotherapy and chemotherapy

    Neoadjuvant immunotherapy and chemotherapy have improved the major pathological response (MPR) in patients with early-stage operable non-small cell lung cancer (NSCLC). This study aimed to assess whether the p...

    Po-Lan Su, Jung-Yueh Chen, Chang-Yao Chu, Yi-Lin Chen, Wan-Li Chen in Scientific Reports (2022)

  7. Article

    Open Access

    Plasmakinetic resection technology for the treatment of benign prostatic hyperplasia: evidence from a systematic review and meta-analysis

    The aim of this study was to compare plasmakinetic resection of the prostate (PKRP) with transurethral resection of the prostate (TURP) for benign prostatic hyperplasia (BPH) in terms of efficacy and safety. P...

    Sheng Li, Joey S.W. Kwong, **an-Tao Zeng, **ao-Lan Ruan, Tong-Zu Liu in Scientific Reports (2015)