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Article
Induction of secondary cell wall biosynthesis genes and their regulators by melatonin in Glycine max
Plant lodging severely reduced crop yield and quality. Different plant growth regulators (PGRs) have been applied to improve lodging resistance through the regulation of physiological changes, especially on th...
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Article
Comparative studies on Fenton-like reactions catalyzed by Fe3O4 loaded inside and outside halloysite nanotubes for the removal of organic pollutants
In this work, Fe3O4 nanoparticles (NPs) loaded inside and outside halloysite nanotubes (HNTs) were prepared and developed as the heterogeneous Fenton-like catalysts for the removal of representative organic pollu...
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Article
Arterial chemotherapy for hepatocellular carcinoma in China: consensus recommendations
Hepatocellular carcinoma (HCC) is one of the most common malignancies and the third leading cause of cancer-related deaths globally. Hepatic arterial infusion chemotherapy (HAIC) treatment is widely accepted a...
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Article
Open AccessTrue intratracheal oxygen concentration delivered by SentriO Oxy™ masks under various respiratory conditions: a bench study
SentriO Oxy™ is a newly available, Food and Drug Administration-approved oxygenation mask system that provides high oxygenation, even on low-flow (5–10 L/min) oxygen. This study aimed to accurately measure the...
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Article
Realization of superhuman intelligence in microstrip filter design based on clustering-reinforcement learning
Microstrip filters are widely used in signal processing because of their light weight, compact structure and high reliability. Designing these filters is very time consuming, and a designer generally needs muc...
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Article
Open AccessEffect of BIM expression on the prognostic value of PD-L1 in advanced non-small cell lung cancer patients treated with EGFR-TKIs
The role of Programmed Cell Death Ligand 1 (PD-L1) expression in predicting epidermal growth factor receptor tyrosine kinase inhibitor (EGFR-TKIs) efficacy remains controversial. Recent studies have highlighte...
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Article
Systematic classification and phylogenetic relationships of the brown-rot fungi within the Polyporales
The brown-rot fungi play an important role in forest ecosystems; they can degrade celluloses and hemicelluloses of wood and maintain nutrient cycling. Some of the brown-rot fungi also have important economic v...
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Article
Open AccessThe surgical resection of the primary tumor increases survival in patients with EGFR-mutant advanced non-small cell lung cancer: a tertiary center cohort study
Tumor resection could increase treatment efficacy of epidermal growth factor receptor (EGFR)-tyrosine kinase inhibitors (TKI) in patients with advanced EGFR-mutant non-small cell lung cancer (NSCLC). This stud...
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Article
Open AccessThe interrelationships between neuronal viability, synaptic integrity, microglial responses, and amyloid-beta formation in an in vitro neurotrauma model
The interrelationships between neuronal viability, synaptic integrity, and microglial responses remain in infancy. In dealing with the question, we induced a stretch injury to evaluate the mechanical effects o...
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Article
Open AccessComparative transcriptome and WGCNA reveal key genes involved in lignocellulose degradation in Sarcomyxa edulis
The developmental transcriptomes of Sarcomyxa edulis were assessed to explore the molecular mechanisms underlying lignocellulose degradation. Six stages were analyzed, spanning the entire developmental process: g...
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Article
Contribution of Mechanical Activation on the Growth of Intermetallic Compound Layers at the Cu/Al Interface During Vacuum Hot Pressing
In the present paper, the Cu/Al diffusion couples were successfully prepared using high-energy ball milling and vacuum hot pressing sintering. The aim of this study was to investigate the influence of mechanic...
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Article
Open AccessWAKE-mediated modulation of cVA perception via a hierarchical neuro-endocrine axis in Drosophila male-male courtship behaviour
The nervous and endocrine systems coordinate with each other to closely influence physiological and behavioural responses in animals. Here we show that WAKE (encoded by wide awake, also known as wake) modulates m...
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Article
Open AccessRisk Factors for Generalization in Patients with Ocular Myasthenia Gravis: A Multicenter Retrospective Cohort Study
Many patients with ocular myasthenia gravis (OMG) progress to generalized disease within the first 2 years of the onset of ocular symptoms. Several retrospective studies have identified risk factors associated...
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Article
Open AccessThe impact of driver mutation on the treatment outcome of early-stage lung cancer patients receiving neoadjuvant immunotherapy and chemotherapy
Neoadjuvant immunotherapy and chemotherapy have improved the major pathological response (MPR) in patients with early-stage operable non-small cell lung cancer (NSCLC). This study aimed to assess whether the p...
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Article
Open AccessSingle-cell RNA sequencing reveals B cell–related molecular biomarkers for Alzheimer’s disease
In recent years, biomarkers have been integrated into the diagnostic process and have become increasingly indispensable for obtaining knowledge of the neurodegenerative processes in Alzheimer’s disease (AD). P...
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Article
Prevention of the return of extinguished fear by disrupting the interaction of neuronal nitric oxide synthase with its carboxy-terminal PDZ ligand
Exposure therapy based on the extinction of fear memory is first-line treatment for post-traumatic stress disorder (PTSD). However, fear extinction is relatively easy to learn but difficult to remember, exting...
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Article
Open AccessSelective and competitive functions of the AAR and UPR pathways in stress-induced angiogenesis
The amino acid response (AAR) and unfolded protein response (UPR) pathways converge on eIF2α phosphorylation, which is catalyzed by Gcn2 and Perk, respectively, under different stresses. This close interconnec...
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Article
Dynamic immune profiling identifies the stronger graft-versus-leukemia (GVL) effects with haploidentical allografts compared to HLA-matched stem cell transplantation
Haploidentical stem cell transplantation (haplo-SCT) achieves superior or at least comparable clinical outcomes to HLA-matched sibling donor transplantation (MSDT) in treating hematological malignancies. To de...
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AnnoLnc: A One-Stop Portal to Systematically Annotate Novel Human Long Noncoding RNAs
While more than a hundred thousand long noncoding RNAs (lncRNAs) have been identified in human genome, their biological functions and regulation are largely elusive. Here we present AnnoLnc, a one-stop online ...
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Article
A new chlorinated non-fullerene acceptor based organic photovoltaic cells over 12% efficiency
The method to fluorinate the terminal group has achieved remarkable success and been widely used to fine-tune the intrinsic properties of organic acceptor materials. Referring to chlorination, however, it gets...
