24 Result(s)
within
**ao-Chun Lu
Science, Humanities and Social Sciences, multidisciplinary
-
Article
Open AccessURI alleviates tyrosine kinase inhibitors-induced ferroptosis by reprogramming lipid metabolism in p53 wild-type liver cancers
The clinical benefit of tyrosine kinase inhibitors (TKIs)-based systemic therapy for advanced hepatocellular carcinoma (HCC) is limited due to drug resistance. Here, we uncover that lipid metabolism reprogramm...
-
Article
Open AccessA ring-like accretion structure in M87 connecting its black hole and jet
The nearby radio galaxy M87 is a prime target for studying black hole accretion and jet formation1,2. Event Horizon Telescope observations of M87 in 2017, at a wavelength of 1.3 mm, revealed a ring-like structure...
-
Article
Open AccessOne-step metallization of weft-knitted fabrics for wearable biaxial strain sensors
One-step direct patterning of high definition conductive tracks in textiles is realized through laser direct writing in combination with a silver organometallic ink developed in-house. Photoreduction, nano-cry...
-
Article
Open AccessParticulate matter may have a limited influence on maternal vitamin D levels
Evidence for an association between the amount of particulate matter (PM) in the atmosphere and vitamin D status of pregnant women is limited. We aimed to examine the independent association between PM and mat...
-
Article
Open AccessReal-world efficacy and safety of pangenotypic direct-acting antivirals against hepatitis C virus infection in Taiwan
Clinical trials showed pangenotypic direct-acting antivirals’ (DAAs) excellent efficacy and safety when treating hepatitis C virus (HCV). Two pangenotypic regimens were examined, glecaprevir/pibrentasvir (GLE/...
-
Article
Ultralow contact resistance between semimetal and monolayer semiconductors
Advanced beyond-silicon electronic technology requires both channel materials and also ultralow-resistance contacts to be discovered1,2. Atomically thin two-dimensional semiconductors have great potential for rea...
-
Article
Open AccessUltrastructural and diffusion tensor imaging studies reveal axon abnormalities in Pompe disease mice
Pompe disease (PD) is caused by lysosomal glycogen accumulation in tissues, including muscles and the central nervous system (CNS). The intravenous infusion of recombinant human acid alpha-glucosidase (rhGAA) ...
-
Article
Open AccessAssociation between regional economic status and renal recovery of dialysis-requiring acute kidney injury among critically ill patients
The association between regional economic status and the probability of renal recovery among patients with dialysis-requiring AKI (AKI-D) is unknown. The nationwide prospective multicenter study enrolled criti...
-
Article
Open Access“A real-world evidence” in reduction of volatile anesthetics by BIS-guided anesthesia
Many well-controlled clinical studies have shown that BIS-guided anesthesia could prevent intraoperative awareness and improve postoperative morbidity and mortality, by optimizing the amount of volatile anesth...
-
Article
Open AccessParapharyngeal fat pad area at the subglosso-supraglottic level is associated with corresponding lateral wall collapse and apnea-hypopnea index in patients with obstructive sleep apnea: a pilot study
The aim of this study was to assess associations between fat pad areas at various anatomic levels and the sites of lateral wall collapse and disease severity in adult patients with obstructive sleep apnea (OSA...
-
Article
Open AccessIncrease Trichomonas vaginalis detection based on urine routine analysis through a machine learning approach
Trichomonas vaginalis (T. vaginalis) detection remains an unsolved problem in using of automated instruments for urinalysis. The study proposes a machine learning (ML)-based strategy to increase the detection rat...
-
Article
Open AccessReversible and selective ion intercalation through the top surface of few-layer MoS2
Electrochemical intercalation of ions into the van der Waals gap of two-dimensional (2D) layered materials is a promising low-temperature synthesis strategy to tune their physical and chemical properties. It i...
-
Article
Open AccessSleep Disturbance and Related Factors in Patients with Nasopharyngeal Carcinoma and Their Family Caregivers Prior to the Initiation of Treatment
Sleep disturbance is a common complaint in cancer patients. However, less is known about the parameters of sleep in patients with nasopharyngeal cancer (NPC) and their family caregivers (FCs) when they are abo...
-
Article
Open AccessInvestigating the Association between Alcohol and Risk of Head and Neck Cancer in Taiwan
Although alcohol is an established risk factor of head and neck cancer (HNC), insufficiencies exist in the literature in several aspects. We analyzed detailed alcohol consumption data (amount and type of alcoh...
-
Article
Open AccessEfficient Generation of Chemically Induced Mesenchymal Stem Cells from Human Dermal Fibroblasts
Human mesenchymal stromal/stem cells (MSCs) are multipotent and currently undergoing hundreds of clinical trials for disease treatments. To date, no studies have generated induced MSCs from skin fibroblasts wi...
-
Article
Open AccessReduced incidence of interstitial pneumonitis after allogeneic hematopoietic stem cell transplantation using a modified technique of total body irradiation
Allogeneic hematopoietic stem cell transplantation is a curative-intent treatment for patients with high-risk hematologic diseases. However, interstitial pneumonitis (IP) and other toxicities remain major conc...
-
Article
Open AccessTranscriptomic profiling of long non-coding RNAs in dermatomyositis by microarray analysis
Long non-coding RNAs (lncRNAs) are prevalently transcribed in the genome and have been found to be of functional importance. However, the potential roles of lncRNAs in dermatomyositis (DM) remain unknown. In t...
-
Article
Open AccessNoise propagation with interlinked feed-forward pathways
Functionally similar pathways are often seen in biological systems, forming feed-forward controls. The robustness in network motifs such as feed-forward loops (FFLs) has been reported previously. In this work,...
-
Article
Open AccessA novel hepatovirus identified in wild woodchuck Marmota himalayana
Hepatitis A virus (HAV) is a hepatotropic picornavirus that causes acute liver disease worldwide. Here, we report on the identification of a novel hepatovirus tentatively named Marmota Himalayana hepatovirus (MHH...
-
Article
Erratum: Genetic diversity and evolutionary dynamics of Ebola virus in Sierra Leone
Nature 524, 93–96 (2015); doi:10.1038/nature14490 This Letter should have contained an associated Creative Commons statement in the Author Information section. In addition, the Fig. 3c legend should have state...
