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Probing water micro-solvation in proteins by water catalysed proton-transfer tautomerism

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  1. Article

    Open Access

    Map** polarization induced surface band bending on the Rashba semiconductor BiTeI

    Surfaces of semiconductors with strong spin-orbit coupling are of great interest for use in spintronic devices exploiting the Rashba effect. BiTeI features large Rashba-type spin splitting in both valence and ...

    Christopher John Butler, Hung-Hsiang Yang, Jhen-Yong Hong in Nature Communications (2014)

  2. Article

    Open Access

    Prevalence and genetic characteristics of Saffold cardiovirus in China from 2009 to 2012

    The epidemiology and clinical features of the Saffold cardiovirus (SAFV) remain ambiguous. The present study was designed to systematically and intensively investigate the epidemiological features of SAFV in p...

    **ao-Ai Zhang, Qing-Bin Lu, Ying Wo, ** Zhao, Dou-Dou Huang in Scientific Reports (2015)

  3. Article

    Open Access

    Genetic diversity and evolutionary dynamics of Ebola virus in Sierra Leone

    The genome sequences of 175 Ebola virus from five districts in Sierra Leone, collected during September–November 2014, show that the rate of virus evolution seems to be similar to that observed during previous...

    Yi-Gang Tong, Wei-Feng Shi, Di Liu, Jun Qian, Long Liang, **ao-Chen Bo, Jun Liu in Nature (2015)

  4. Article

    Erratum: Genetic diversity and evolutionary dynamics of Ebola virus in Sierra Leone

    Nature 524, 93–96 (2015); doi:10.1038/nature14490 This Letter should have contained an associated Creative Commons statement in the Author Information section. In addition, the Fig. 3c legend should have state...

    Yi-Gang Tong, Wei-Feng Shi, Di Liu, Jun Qian, Long Liang, **ao-Chen Bo, Jun Liu in Nature (2015)

  5. Article

    Open Access

    A novel hepatovirus identified in wild woodchuck Marmota himalayana

    Hepatitis A virus (HAV) is a hepatotropic picornavirus that causes acute liver disease worldwide. Here, we report on the identification of a novel hepatovirus tentatively named Marmota Himalayana hepatovirus (MHH...

    Jie-mei Yu, Li-li Li, Cui-yuan Zhang, Shan Lu, Yuan-yun Ao in Scientific Reports (2016)

  6. Article

    Open Access

    Noise propagation with interlinked feed-forward pathways

    Functionally similar pathways are often seen in biological systems, forming feed-forward controls. The robustness in network motifs such as feed-forward loops (FFLs) has been reported previously. In this work,...

    Surendhar Reddy Chepyala, Yi-Chen Chen, Ching-Cher Sanders Yan in Scientific Reports (2016)

  7. Article

    Open Access

    Transcriptomic profiling of long non-coding RNAs in dermatomyositis by microarray analysis

    Long non-coding RNAs (lncRNAs) are prevalently transcribed in the genome and have been found to be of functional importance. However, the potential roles of lncRNAs in dermatomyositis (DM) remain unknown. In t...

    Qing-Lin Peng, Ya-Mei Zhang, Han-Bo Yang, **ao-Ming Shu, **n Lu in Scientific Reports (2016)

  8. Article

    Open Access

    Reduced incidence of interstitial pneumonitis after allogeneic hematopoietic stem cell transplantation using a modified technique of total body irradiation

    Allogeneic hematopoietic stem cell transplantation is a curative-intent treatment for patients with high-risk hematologic diseases. However, interstitial pneumonitis (IP) and other toxicities remain major conc...

    Yun Chiang, Cheng-Hong Tsai, Sung-Hsin Kuo, Chieh-Yu Liu, Ming Yao in Scientific Reports (2016)

  9. Article

    Open Access

    Efficient Generation of Chemically Induced Mesenchymal Stem Cells from Human Dermal Fibroblasts

    Human mesenchymal stromal/stem cells (MSCs) are multipotent and currently undergoing hundreds of clinical trials for disease treatments. To date, no studies have generated induced MSCs from skin fibroblasts wi...

    Pei-Lun Lai, Hsuan Lin, Shang-Fu Chen, Shang-Chih Yang in Scientific Reports (2017)

  10. Article

    Open Access

    Investigating the Association between Alcohol and Risk of Head and Neck Cancer in Taiwan

    Although alcohol is an established risk factor of head and neck cancer (HNC), insufficiencies exist in the literature in several aspects. We analyzed detailed alcohol consumption data (amount and type of alcoh...

    Cheng-Chih Huang, Jenn-Ren Hsiao, Wei-Ting Lee, Yao-Chou Lee in Scientific Reports (2017)

  11. Article

    Open Access

    Sleep Disturbance and Related Factors in Patients with Nasopharyngeal Carcinoma and Their Family Caregivers Prior to the Initiation of Treatment

    Sleep disturbance is a common complaint in cancer patients. However, less is known about the parameters of sleep in patients with nasopharyngeal cancer (NPC) and their family caregivers (FCs) when they are abo...

    **ao-Ying Lai, Zhong-Min Tang, **ao-Dong Zhu, Ling Li, Xue-Yan Qin in Scientific Reports (2018)

  12. Article

    Open Access

    Reversible and selective ion intercalation through the top surface of few-layer MoS2

    Electrochemical intercalation of ions into the van der Waals gap of two-dimensional (2D) layered materials is a promising low-temperature synthesis strategy to tune their physical and chemical properties. It i...

    **song Zhang, Ankun Yang, ** Wu, Jorik van de Groep, Peizhe Tang in Nature Communications (2018)

  13. Article

    Open Access

    Increase Trichomonas vaginalis detection based on urine routine analysis through a machine learning approach

    Trichomonas vaginalis (T. vaginalis) detection remains an unsolved problem in using of automated instruments for urinalysis. The study proposes a machine learning (ML)-based strategy to increase the detection rat...

    Hsin-Yao Wang, Chung-Chih Hung, Chun-Hsien Chen, Tzong-Yi Lee in Scientific Reports (2019)

  14. Article

    Open Access

    Parapharyngeal fat pad area at the subglosso-supraglottic level is associated with corresponding lateral wall collapse and apnea-hypopnea index in patients with obstructive sleep apnea: a pilot study

    The aim of this study was to assess associations between fat pad areas at various anatomic levels and the sites of lateral wall collapse and disease severity in adult patients with obstructive sleep apnea (OSA...

    Hung-Chin Chen, Chao-Jan Wang, Yu-Lun Lo, Hao-Chun Hsu in Scientific Reports (2019)

  15. Article

    Open Access

    “A real-world evidence” in reduction of volatile anesthetics by BIS-guided anesthesia

    Many well-controlled clinical studies have shown that BIS-guided anesthesia could prevent intraoperative awareness and improve postoperative morbidity and mortality, by optimizing the amount of volatile anesth...

    Yan-Yuen Poon, Han-Chen Chang, Min-Hsien Chiang, Kuo-Chuan Hung in Scientific Reports (2020)

  16. Article

    Open Access

    Association between regional economic status and renal recovery of dialysis-requiring acute kidney injury among critically ill patients

    The association between regional economic status and the probability of renal recovery among patients with dialysis-requiring AKI (AKI-D) is unknown. The nationwide prospective multicenter study enrolled criti...

    Chih-Chung Shiao, Yu-Hsing Chang, Ya-Fei Yang, En-Tzu Lin in Scientific Reports (2020)

  17. Article

    Open Access

    Ultrastructural and diffusion tensor imaging studies reveal axon abnormalities in Pompe disease mice

    Pompe disease (PD) is caused by lysosomal glycogen accumulation in tissues, including muscles and the central nervous system (CNS). The intravenous infusion of recombinant human acid alpha-glucosidase (rhGAA) ...

    Ni-Chung Lee, Wei-Hao Peng, Li-Kai Tsai, Yen-Hsu Lu, Hao-Chun Wang in Scientific Reports (2020)

  18. Article

    Open Access

    Real-world efficacy and safety of pangenotypic direct-acting antivirals against hepatitis C virus infection in Taiwan

    Clinical trials showed pangenotypic direct-acting antivirals’ (DAAs) excellent efficacy and safety when treating hepatitis C virus (HCV). Two pangenotypic regimens were examined, glecaprevir/pibrentasvir (GLE/...

    Kao-Chi Chang, Shui-Yi Tung, Kuo-Liang Wei, Chen-Heng Shen in Scientific Reports (2021)

  19. Article

    Open Access

    Particulate matter may have a limited influence on maternal vitamin D levels

    Evidence for an association between the amount of particulate matter (PM) in the atmosphere and vitamin D status of pregnant women is limited. We aimed to examine the independent association between PM and mat...

    Chong Li, Ya-qin Gong, Yun-yu **a, **ao-chun Wang, Lin Chen in Scientific Reports (2022)

  20. Article

    Open Access

    One-step metallization of weft-knitted fabrics for wearable biaxial strain sensors

    One-step direct patterning of high definition conductive tracks in textiles is realized through laser direct writing in combination with a silver organometallic ink developed in-house. Photoreduction, nano-cry...

    Chao-Yi Tai, Chun-Yu Lin, Tang-Chun Liu, Lu-Chiang Jia, Thomas Jones in Scientific Reports (2022)

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