430 Result(s)
within
Immunology
**ao-**a Jiang
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Article
Membrane endopeptidases of human neutrophil
Recent studies using inhibitors or synthetic substrates of serine protease suggest that membrane protease activity may be essential for neutrophil chemotaxis, phagocytosis, degranulation, and superoxide produc...
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Chapter
The Effects of High and Low Chromium Yeast Supplementation on Glucose Metabolism of Noninsulin Dependent Diabetic Patients
Chromium in the trivalent state is an essential element required for normal carbohydrate and lipid metabolism; in the form of hexavalent compounds it is a carcinogen. Chromium deficient animals display impaire...
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Chapter
Hemolymph Proteinases in Immune Responses of Manduca sexta
Extracellular signal transduction pathways in blood are often composed of cascades of serine proteinases to amplify rapidly a response to wounding or infection. The vertebrate blood coagulation and complement ...
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Chapter
Galectins and Other Endogenous Carbohydrate-Binding Proteins of Animal Bladder
Defects in the glycocalyx of the bladder epithelium may be related to the opment of bladder diseases including interstitial cystitis which is a chronic bladder e of unknown etiology. Indirect evidence has impl...
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Article
Disulfide exchange in domain 2 of CD4 is required for entry of HIV-1
CD4, a member of the immunoglobulin superfamily of receptors that mediates cell-cell interactions in the immune system, is the primary receptor for HIV-1. The extracellular portion of CD4 is a concatenation of...
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Article
Construction of DNA vaccines and their induced protective immunity against experimental Eimeria tenella infection
In an attempt to construct a DNA vaccine against chicken coccidiosis, the TA4 gene of Eimeria tenella strain BJ was ligated to the mammalian expression vector pcDNA3.1/Zeo(+) to give pcDNA3.1-TA4 (pcDT). Then, E...
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Article
Construction of phospholamban antisense RNA recombinant adeno-associated virus vector and its effects in rat cardiomyocytes
To construct a recombinant adeno-associated virus (rAAV) vector containing gene encoding phospholamban antisense RNA (asPLB), and analyse its effect on expression of PLB, expression and activity of sarco-endop...
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Article
Swietenia mahagony extract shows agonistic activity to PPAR γ and gives ameliorative effects on diabetic db/db mice
To search the peroxisome proliferator-activated receptor γ (PPARγ) agonists from Swietenia mahagony extract (SmE) and observe the possible ameliorative effects of SmE on diabetic db/db mice.
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Article
Effects of spider Macrothele raven venom on cell proliferation and cytotoxicity in HeLa cells
To examine the effect of venom from the spider Macrothele raven on cell proliferation and cytotoxicity in human cervical carcinoma, HeLa cells.
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Article
Induction of leukemia cell apoptosis by cheliensisin A involves downregulation of Bcl-2 expression
To investigate the apoptosis-inducing effect of cheliensisin A (GC-51), a novel styryl-lactone isolated from Goniothalamus cheliensis, on human promyelocytic leukemia HL-60 cells and the mechanism of action invol...
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Article
Protective effects of bendazac lysine on early experimental diabetic nephropathy in rats
To investigate the preventive and protective effects of bendazac lysine (BDL) on experimental early diabetic nephropathy (DN) rats.
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Article
Identification of human dopamine D1-like receptor agonist using a cell-based functional assay
To establish a cell-based assay to screen human dopamine D1 and D5 receptor agonists against compounds from a natural product compound library.
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Article
Effects of CpG-ODN on gene expression in formation of foam cells
To investigate the effects of CpG-oligodeoxynucleotide (CpG-ODN) on the formation of macrophage foam cells and related gene expression.
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Article
Induction of liver cytochrome P450 1A2 expression by flutamide in rats
To investigate the modulation of liver cytochrome P450 1A2 (CYP1A2) expression by giving flutamide to adult rats.
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Article
Molecular dynamics simulations of interaction between protein-tyrosine phosphatase 1B and a bidentate inhibitor
To investigate the dynamic properties of protein-tyrosine phosphatase (PTP) 1B and reveal the structural factors responsible for the high inhibitory potency and selectivity of the inhibitor SNA for PTP1B.
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Article
High density lipoprotein 3 inhibits oxidized low density lipoprotein-induced apoptosis via promoting cholesterol efflux in RAW264.7 cells
To investigate the protective effect of high density lipoprotein 3 (HDL3) on oxidized low density lipoprotein (ox-LDL)-induced apoptosis in RAW264.7 cells.
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Article
Effective use of corticosteroids in treatment of plastic bronchitis with hemoptysis in Chinese adults
To investigate whether corticosteroids are effective in the treatment of plastic bronchitis with hemoptysis.
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Article
Differentiation of bone marrow mesenchymal stem cells induced by myocardial medium under hypoxic conditions
To explore whether bone marrow mesenchymal stem cells (MSC) can differentiate into myocardial-like cells induced by myocardial medium, especially the hypoxia/reoxygenation-conditioned medium of cardiomyocytes.
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Article
Design, synthesis and antitumor evaluation of a new series of N-substituted-thiourea derivatives
To design and synthesize a novel class of protein tyrosine kinase inhibitors, featuring the N-(2-oxo-1,2-dihydroquinolin-3-yl-methyl)-thiourea framework.
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Article
Design, synthesis, antitumor evaluations and molecular modeling studies of novel 3,5-substituted indolin-2-one derivatives
To design and synthesize a novel class of antitumor agents, featuring the 3, 5-substituted indolin-2-one framework.
