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  1. No Access

    Article

    Root system architecture change in response to waterlogging stress in a 448 global collection of rapeseeds (Brassica napus L.)

    A novel image-based screening method for precisely identifying genotypic variations in rapeseed RSA under waterlogging stress was developed. Five key root traits were confirmed as good indicators of waterloggi...

    Naseeb Ullah, Fang Qian, Rudan Geng, Yujun Xue, Wenjie Guan, Gaoxiang Ji, Hao Li in Planta (2024)

  2. No Access

    Article

    Calcium Nanoparticles and Abscisic Acid Improve Drought Tolerance, Mineral Nutrients Uptake and Inhibitor-Mediated Photosystem II Performance in Brassica napus

    Plant yield is severely hampered by drought, affirming the urgent need to develop strategies to improve plant growth and drought tolerance. The synergistic application of ABA and calcium nanoparticles (Ca-NPs)...

    Ahsan Ayyaz, Yingying Zhou, Iram Batool in Journal of Plant Growth Regulation (2024)

  3. No Access

    Article

    Lack of Hematodinium microscopic detection in crustaceans at the northern and southern ends of the Wadden Sea and an update of its distribution in Europe

    Hematodinium is a parasitic dinoflagellate with a wide distribution along the European coastline. We investigated whether Hematodinium occurs in the Wadden Sea, a large tidal flat system spanning the Netherlands,...

    Qian Huang, Andreas M. Waser, Caiwen Li, David W. Thieltges in Marine Biology (2024)

  4. Article

    Open Access

    The functional divergence of homologous GPAT9 genes contributes to the erucic acid content of Brassica napus seeds

    The early allopolyploid Brassica napus was a hybrid of two Brassica species, that had undergone a whole genome duplication event followed by genome restructuring, including deletions and small scale duplications....

    Hongbo Liu, **bo Zhu, Bingxin Zhang, Qingyang Li, Cui Liu, Qian Huang in BMC Plant Biology (2024)

  5. Article

    Open Access

    Whole genome analysis of Bacillus amyloliquefaciens TA-1, a promising biocontrol agent against Cercospora arachidicola pathogen of early leaf spot in Arachis hypogaea L

    Early leaf spot disease, caused by Cercospora arachidicola, is a devastating peanut disease that has severely impacted peanut production and quality. Chemical fungicides pollute the environment; however, Bacillus

    Chen Wang, Taswar Ahsan, Ao Ding, Di Han, Chao-Qun Zang, Yu-Qian Huang in BMC Plant Biology (2023)

  6. No Access

    Article

    Knowledge Map and Global Trends in Root Exudates Research from 2012 to 2021: a Bibliometric Analysis

    The number of publications on root exudates has been increasing continuously, because root exudates play a key role in soil biochemical cycles and plant-soil feedbacks. However, global trend and research hotpo...

    **n Zheng, Dongming Chen, Jiqiong Zhou in Journal of Soil Science and Plant Nutrition (2023)

  7. No Access

    Article

    Inhibition of ALG3 stimulates cancer cell immunogenic ferroptosis to potentiate immunotherapy

    Immune checkpoint blockade therapy has drastically improved the prognosis of certain advanced-stage cancers. However, low response rates and immune-related adverse events remain important limitations. Here, we...

    Pei Liu, Cha Lin, Zheyu Liu, Chenchen Zhu in Cellular and Molecular Life Sciences (2022)

  8. Article

    Open Access

    Disruption of three polyamine uptake transporter genes in rice by CRISPR/Cas9 gene editing confers tolerance to herbicide paraquat

    Weeds are a major biotic constraint that can cause dramatic crop production losses. Herbicide technology has been widely used by farmers as the most cost-effective weed control measure, and development of new ...

    Yu-Shu Lyu, Li-Miao Cao, Wen-Qian Huang, Jian-**ang Liu, Hai-** Lu in aBIOTECH (2022)

  9. Article

    Open Access

    Mechanism of cancer stemness maintenance in human liver cancer

    Primary liver cancer mainly includes the following four types: hepatocellular carcinoma (HCC), cholangiocarcinoma (CCA), hepatoblastoma (HB), and combined hepatocellular carcinoma and cholangiocarcinoma (cHCC-...

    Ning Liang, Tao Yang, Qian Huang, Pengfei Yu, Chaoxu Liu in Cell Death & Disease (2022)

  10. No Access

    Article

    Development of MEMS directed evolution strategy for multiplied throughput and convergent evolution of cytochrome P450 enzymes

    Directed evolution (DE) inspired by natural evolution (NE) has been achieving tremendous successes in protein/enzyme engineering. However, the conventional “one-protein-for-one-task” DE cannot match the “multi...

    Li Ma, Fengwei Li, **ngwang Zhang, Hui Chen, Qian Huang in Science China Life Sciences (2022)

  11. Article

    Open Access

    Six New 3,5-Dimethylcoumarins from Chelonopsis praecox, Chelonopsis odontochila and Chelonopsis pseudobracteata

    Ten 3,5-dimethylcoumarins (16 and 811) involving six new ones (16), together with a known 3-methylcoumarin (7), were isolated from the aerial parts of three Chelonopsis plants, C. praecox, C. odontochila, and

    Chang-An Geng, Zhen-Tao Deng, Qian Huang in Natural Products and Bioprospecting (2021)

  12. No Access

    Article

    Pharmacological inhibition of BACE1 suppresses glioblastoma growth by stimulating macrophage phagocytosis of tumor cells

    Glioblastoma (GBM) contains abundant tumor-associated macrophages (TAMs). The majority of TAMs are tumor-promoting macrophages (pTAMs), while tumor-suppressive macrophages (sTAMs) are the minority. Thus, repro...

    Kui Zhai, Zhi Huang, Qian Huang, Weiwei Tao, **aoguang Fang, Aili Zhang in Nature Cancer (2021)

  13. Article

    Open Access

    Gut microbiota changes in preeclampsia, abnormal placental growth and healthy pregnant women

    Preeclampsia (PE) is a condition of high blood pressure that is usually concurrent with proteinuria in pregnancy. PE complicates the management of both maternal and fetal health and contributes to most adverse...

    Lihui Huang, Min Cai, Li Li, **n Zhang, Yang Xu, Jianhua **ao in BMC Microbiology (2021)

  14. No Access

    Article

    The parasitic dinoflagellate Hematodinium infects marine crustaceans

    Hematodinium is a type of parasitic dinoflagellate that infects marine crustaceans globally. The parasite lives mainly in the hemolymph or hemocoels of affected hosts, and results in mortalities due to malfunctio...

    Caiwen Li, Meng Li, Qian Huang in Marine Life Science & Technology (2021)

  15. Article

    Open Access

    Extracellular DNA released by glycine-auxotrophic Staphylococcus epidermidis small colony variant facilitates catheter-related infections

    Though a definitive link between small colony variants (SCVs) and implant-related staphylococcal infections has been well-established, the specific underlying mechanism remains an ill-explored field. The prese...

    Junlan Liu, Zhen Shen, ** Tang, Qian Huang, Ying Jian, Yao Liu in Communications Biology (2021)

  16. No Access

    Article

    SAA1 regulates pro-labour mediators in term labour by activating YAP pathway

    Term labour is associated with activation of inflammation which results in myometrial contractility, cervical ripening and decidual/membrane rupture. Serum amyloid A1 (SAA1) is an acute response protein, whose...

    Yanmin Jiang, Li Pin, Weiqun Shi, Qian Huang in Molecular and Cellular Biochemistry (2021)

  17. No Access

    Article

    The cytoplasmic loops of AgrC contribute to the quorum-sensing activity of Staphylococcus aureus

    In Staphylococcus aureus, the accessory gene regulator (agr) quorum-sensing system is thought to play an important role in biofilm formation. The histidine kinase AgrC is one of the agr system components and acti...

    Qian Huang, Yihui **e, Ziyu Yang, Danhong Cheng, Lei He in Journal of Microbiology (2021)

  18. Article

    Open Access

    Comparison of the cytoplastic genomes by resequencing: insights into the genetic diversity and the phylogeny of the agriculturally important genus Brassica

    The genus Brassica mainly comprises three diploid and three recently derived allotetraploid species, most of which are highly important vegetable, oil or ornamental crops cultivated worldwide. Despite being exten...

    Jiangwei Qiao, **aojun Zhang, Biyun Chen, Fei Huang, Kun Xu, Qian Huang in BMC Genomics (2020)

  19. Article

    Open Access

    Protective mechanisms of melatonin against selenium toxicity in Brassica napus: insights into physiological traits, thiol biosynthesis and antioxidant machinery

    The ubiquitous signaling molecule melatonin (N-acetyl-5-methoxytryptamine) (MT) plays vital roles in plant development and stress tolerance. Selenium (Se) may be phytotoxic at high concentrations. Interactions be...

    Zaid Ulhassan, Qian Huang, Rafaqat Ali Gill, Skhawat Ali in BMC Plant Biology (2019)

  20. No Access

    Article

    Nanoscale fiber-optic force sensors for mechanical probing at the molecular and cellular level

    There is an ongoing need to develop ultrasensitive nanomechanical instrumentation that has high spatial and force resolution, as well as an ability to operate in various biological environments. Here, we prese...

    Yuesong Shi, Beril Polat, Qian Huang, Donald J. Sirbuly in Nature Protocols (2018)

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