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  1. Article

    Open Access

    Comprehensive analysis of T-cell regulatory factors and tumor immune microenvironment in stomach adenocarcinoma

    Gastric cancer (GC) is one of the most prevalent malignant tumors worldwide and is associated with high morbidity and mortality rates. However, the specific biomarkers used to predict the postoperative prognos...

    Shuchang Wang, Weifeng Zhang, **nrui Wu, Zhu Zhu, Yuanbiao Chen, Wangrui Liu… in BMC Cancer (2024)

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  2. No Access

    Article

    Construction of cuproptosis signature based on bioinformatics and experimental validation in clear cell renal cell carcinoma

    Cuproptosis was defined as a novel nonapoptotic cell death pathway and its potential function in clear cell renal cell carcinoma (ccRCC) remains unclear.

    ** Tian, Shuxuan Zhu, Wangrui Liu, **nrui Wu… in Journal of Cancer Research and Clinical On… (2023)

  3. No Access

    Article

    Deciphering the implications of mitophagy-related signatures in clinical outcomes and microenvironment heterogeneity of clear cell renal cell carcinoma

    The role of mitophagy in various cancer-associated biological processes is well recognized. Nonetheless, the comprehensive implications of mitophagy in clear cell renal cell carcinoma (ccRCC) necessitate furth...

    Jianfeng **ang, Wangrui Liu, Shifan Liu… in Journal of Cancer Research and Clinical On… (2023)

  4. No Access

    Article

    Prognostic value, DNA variation and immunologic features of a tertiary lymphoid structure-related chemokine signature in clear cell renal cell carcinoma

    The tumor microenvironment (TME) and tertiary lymphoid structures (TLS) affect the occurrence and development of cancers. How the immune contexture interacts with the phenotype of clear cell renal cell carcino...

    Wenhao Xu, Chunguang Ma, Wangrui Liu… in Cancer Immunology, Immunotherapy (2022)

  5. Article

    Open Access

    Deciphering the role of miR-187-3p/LRFN1 axis in modulating progression, aerobic glycolysis and immune microenvironment of clear cell renal cell carcinoma

    Clear cell renal cell carcinoma (ccRCC) is one of the most common malignant genitourinary cancers with high recurrence risk worldwide. Recently, multi-omics data facilitate obtaining a molecular landscape of t...

    Wenhao Xu, Wangrui Liu, Aihetaimujiang Anwaier, ** Tian, Jiaqi Su… in Discover Oncology (2022)

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  6. Article

    Open Access

    A bioinformatic analysis study of m7G regulator-mediated methylation modification patterns and tumor microenvironment infiltration in glioblastoma

    Glioblastoma is one of the most common brain cancers in adults, and is characterized by recurrence and little curative effect. An effective treatment for glioblastoma patients remains elusive worldwide. 7-meth...

    **nrui Wu, Chuanyu Li, Zhisu Wang, Yundi Zhang, Shifan Liu, Siqi Chen… in BMC Cancer (2022)

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  7. No Access

    Article

    In vitro antitumor mechanism of a novel cyclin-dependent kinase inhibitor CDKI-83

    Cancer is regarded as a proliferative disorder. Inhibition of cyclin-dependent kinases (CDKs), which are the key regulators of the cell-cycle and RNA transcription, represents an attractive strategy for cancer...

    **angrui Liu, Frankie Lam, Shenhua Shi, Peter M. Fischer… in Investigational New Drugs (2012)