-
Article
A catalytic hairpin assembly–based Förster resonance energy transfer sensor for ratiometric detection of ochratoxin A in food samples
Ochratoxin A (OTA) poses severe risks to the environment and human health, making the development of an accurate and sensitive analytical method for OTA detection essential. In this study, a catalytic hairpin ...
-
Article
G-quadruplex-selective iridium(III) complex as a novel electrochemiluminescence probe for switch-on assay of double-stranded DNA
In this work, we synthesized an iridium(III) complex and studied its selective ability to interact with a specific G-quadruplex DNA sequence (GTGGGTAGGGCGGGTTGG). Results showed that the iridium(III) complex e...
-
Article
One-step and ultrasensitive ATP detection by using positively charged nano-gold@graphene oxide as a versatile nanocomposite
A versatile nanocomposite was simply prepared based upon the electrostatic adsorption of positively charged gold nanoparticles with negatively charged graphene oxide (nano-gold@GO), and utilized as a novel fluore...
-
Article
Electrochemical aptamer-based determination of protein tyrosine kinase-7 using toehold-mediated strand displacement amplification on gold nanoparticles and graphene oxide
An electrochemical method is described for ultrasensitive determination of protein tyrosine kinase-7 (PTK7). It is based on (a) the use of positively charged gold nanoparticles (AuNPs) and negatively charged g...
-
Article
Fluorometric determination of mercury(II) using positively charged gold nanoparticles, DNA-templated silver nanoclusters, T-Hg(II)-T interaction and exonuclease assisted signal amplification
The authors describe a method for detection of Hg2+ by using positively charged gold nanoparticles ((+)AuNPs) as a quencher of the fluorescence of DNA-capped silver nanoclusters (DNA-AgNCs) which are negatively c...
-
Article
A gold nanoparticle based fluorescent probe for simultaneous recognition of single-stranded DNA and double-stranded DNA
A fluorescent method is described for simultaneous recognition of single-stranded DNA (ssDNA) and double-stranded DNA (dsDNA). It is based on the quenching of the fluorescence of fluorophore labeled DNA probes...
-
Article
Open AccessA cyclometalated iridium(III) complex used as a conductor for the electrochemical sensing of IFN-γ
A novel iridium(III) complex was prepared and used as a conductor for sensitive and enzyme-free electrochemical detection of interferon gamma (IFN-γ). This assay is based on a dual signal amplification mechani...
-
Article
Open AccessSensitive detection of miRNA by using hybridization chain reaction coupled with positively charged gold nanoparticles
Positively charged gold nanoparticles (+)AuNPs can adsorb onto the negatively charged surface of single-stranded DNA (ssDNA) or double-stranded DNA (dsDNA). Herein, long-range dsDNA polymers could form based o...
-
Article
Open AccessApplication of iridium(III) complex in label-free and non-enzymatic electrochemical detection of hydrogen peroxide based on a novel “on-off-on” switch platform
We herein report a label-free and non-enzymatic electrochemical sensor for the highly sensitive detection of hydrogen peroxide (H2O2) based on a novel “on-off-on” switch system. In our design, MB was used as an e...
-
Article
Open AccessTriplex DNA: A new platform for polymerase chain reaction – based biosensor
Non - specific PCR amplification and DNA contamination usually accompany with PCR process, to overcome these problems, here we establish a sensor for thrombin by sequence - specific recognition of the PCR prod...
-
Article
Glucose detection at attomole levels using dynamic light scattering and gold nanoparticles
Glucose is directly related to brain activity and to diabetes. Therefore, develo** a rapid and sensitive method for glucose detection is essential. Here, label-free glucose detection at attomole levels was r...