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Article
AIDA directly connects sympathetic innervation to adaptive thermogenesis by UCP1
The sympathetic nervous system–catecholamine–uncoupling protein 1 (UCP1) axis plays an essential role in non-shivering adaptive thermogenesis. However, whether there exists a direct effector that physically co...
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Article
Open AccessLncRNA IMFlnc1 promotes porcine intramuscular adipocyte adipogenesis by sponging miR-199a-5p to up-regulate CAV-1
Local Chinese local pig breeds have thinner muscle fiber and higher intramuscular-fat (IMF) content. But its regulation mechanism has not been discussed in-depth. Studies indicated that long non coding RNAs (l...
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Article
Open AccessLong-term anti-inflammatory diet in relation to improved breast cancer prognosis: a prospective cohort study
Inflammation-modulating nutrients and inflammatory markers are established cancer risk factors, however, evidence regarding the association between post-diagnosis diet-associated inflammation and breast cancer...
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Article
Open AccessMicroRNA-101 inhibits invasion and angiogenesis through targeting ITGA3 and its systemic delivery inhibits lung metastasis in nasopharyngeal carcinoma
Clinically, distant metastasis after primary treatment remains a key problem in nasopharyngeal carcinoma (NPC), and the treatment outcome of metastatic NPC remains disappointing, so there is a pressing need to...
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Article
Effect of Trehalose on PC12 Cells Overexpressing Wild-Type or A53T Mutant α-synuclein
Accumulation of α-synuclein (α-Syn) is a common pathology for both familiar and sporadic Parkinson’s disease (PD), enhancing its clearance might be a promising strategy for treating PD. To assess the potential...