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Open AccessThe acyl-CoA-binding protein VdAcb1 is essential for carbon starvation response and contributes to virulence in Verticillium dahliae
In the face of carbon, nitrogen, and phosphorus starvation, microorganisms have evolved adaptive mechanisms to maintain growth. In a previous study, we identified a protein predicted to contain acyl-CoA-bindin...
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Article
Advanced modeling of the absorption enhancement of black carbon particles in chamber experiments by considering the morphology and coating thickness
Measurements studies have shown that the absorption of radiation by black carbon (BC) increases as the particles age. However, there are significant discrepancies between the measured and modeled absorption en...
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Article
Open AccessTherapeutic potentials of allicin in cardiovascular disease: advances and future directions
Cardiovascular disease (CVD) remains the predominant cause of mortality and disability worldwide. Against this backdrop, finding effective drugs for the pharmacological treatment of CVD has become one of the m...
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Article
Tongxinluo Activates PI3K/AKT Signaling Pathway to Inhibit Endothelial Mesenchymal Transition and Attenuate Myocardial Fibrosis after Ischemia-Reperfusion in Mice
To investigate the potential role of Tongxinluo (TXL) in attenuating myocardial fibrosis after myocardial ischemia-reperfusion injury (MIRI) in mice.
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Open AccessAuthor Correction: On the mechanism of wogonin against acute monocytic leukemia using network pharmacology and experimental validation
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Article
Open AccessLactate secreted by glycolytic conjunctival melanoma cells attracts and polarizes macrophages to drive angiogenesis in zebrafish xenografts
Conjunctival melanoma (CoM) is a rare but potentially lethal cancer of the eye, with limited therapeutic option for metastases. A better understanding how primary CoM disseminate to form metastases is urgently...
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Article
Psychological effects of perceived crowding on time displacement behavior: mediating roles of perceived control loss and negative emotion, moderated by perceived waiting time
This study, grounded in the cognitive evaluation theory of psychology, examines how perceived crowding affects tourists’ time displacement behavior in crowded destinations, drawing on data from 494 analyzed qu...
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Article
Open AccessMETTL1-mediated tRNA m7G methylation and translational dysfunction restricts breast cancer tumorigenesis by fueling cell cycle blockade
RNA modifications of transfer RNAs (tRNAs) are critical for tRNA function. Growing evidence has revealed that tRNA modifications are related to various disease processes, including malignant tumors. However, t...
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Article
Open AccessEnvironment-induced heritable variations are common in Arabidopsis thaliana
Parental or ancestral environments can induce heritable phenotypic changes, but whether such environment-induced heritable changes are a common phenomenon remains unexplored. Here, we subject 14 genotypes of Arab...
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Open AccessTranscriptome analysis of Gossypium hirsutum cultivar Zhongzhimian No.2 uncovers the gene regulatory networks involved in defense against Verticillium dahliae
Cotton is globally important crop. Verticillium wilt (VW), caused by Verticillium dahliae, is the most destructive disease in cotton, reducing yield and fiber quality by over 50% of cotton acreage. Breeding resis...
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Open AccessCorrection: Assessing immunogenicity of CRISPR‑NCas9 engineered strain against porcine epidemic diarrhea virus
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Open AccessInsights into the biocontrol and plant growth promotion functions of Bacillus altitudinis strain KRS010 against Verticillium dahliae
Verticillium wilt, caused by the fungus Verticillium dahliae, is a soil-borne vascular fungal disease, which has caused great losses to cotton yield and quality worldwide. The strain KRS010 was isolated from the ...
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Article
Open AccessNGEF is a potential prognostic biomarker and could serve as an indicator for immunotherapy and chemotherapy in lung adenocarcinoma
Neuronal guanine nucleotide exchange factor (NGEF) plays a key role in several cancers; however, its role in lung adenocarcinoma (LUAD) remains unclear. The aim of this study was to evaluate the efficacy of NG...
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Extracellular volume fraction derived from dual-energy CT: a potential predictor for acute pancreatitis after pancreatoduodenectomy
To investigate the value of extracellular volume (ECV) fraction and fat fraction (FF) derived from dual- energy CT (DECT) for predicting postpancreatectomy acute pancreatitis (PPAP) after pancreatoduodenectomy...
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Article
Oroxylin A-induced Trained Immunity Promotes LC3-associated Phagocytosis in Macrophage in Protecting Mice Against Sepsis
Sepsis is defined as a dysregulated host response to infection that leads to multiorgan failure. Innate immune memory, i.e., “trained immunity”, can result in stronger immune responses and provide protection a...
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Open AccessFunctional analysis of the mating type genes in Verticillium dahliae
Populations of the plant pathogenic fungus Verticillium dahliae display a complex and rich genetic diversity, yet the existence of sexual reproduction in the fungus remains contested. As pivotal genes, MAT genes ...
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Article
The comparision among euploidy of preimplantation blastocysts in different controlled ovary stimulation (COH) protocols
To compare differences in euploidy rates for blastocysts in preimplantation genetic testing for aneuploidy (PGT-A) cycles after gonadotropin-releasing hormone agonist (GnRH-a) long and short protocols, GnRH-an...
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Article
Open AccessOn the mechanism of wogonin against acute monocytic leukemia using network pharmacology and experimental validation
Wogonin is a natural flavone compound from the plant Scutellaria baicalensis, which has a variety of pharmacological activities such as anti-cancer, anti-virus, anti-inflammatory, and immune regulation. Howeve...
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Article
Open AccessMSCs promote the efferocytosis of large peritoneal macrophages to eliminate ferroptotic monocytes/macrophages in the injured endometria
Endometria are one of the important components of the uterus, which is located in the peritoneal cavity. Endometrial injury usually leads to intrauterine adhesions (IUA), accompanied by inflammation and cell d...
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Article
Effect of spreading time on the taste quality of steamed green tea based on E-tongue evaluation and chemometric statistical analysis
Processing plays a decisive role in the flavor of steamed green tea (SGT), especially spreading, which is the basis of its taste formation. However, the effect of spreading time on the taste quality of ‘Qianch...
