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  1. Article

    Open Access

    Legionella maintains host cell ubiquitin homeostasis by effectors with unique catalytic mechanisms

    The intracellular bacterial pathogen Legionella pneumophila modulates host cell functions by secreting multiple effectors with diverse biochemical activities. In particular, effectors of the SidE family interfere...

    Jiaqi Fu, Siying Li, Hongxin Guan, Chuang Li, Yan-Bo Zhao in Nature Communications (2024)

  2. Article

    Open Access

    Transcriptome sequencing of garlic reveals key genes related to the heat stress response

    With global warming, heat stress has become an important factor that seriously affects crop yield and quality. Therefore, understanding plant responses to heat stress is important for agricultural practice, bu...

    Qing-Qing Yang, Feng Yang, Can-Yu Liu, Yong-Qiang Zhao, Meng-Yao Li in Scientific Reports (2024)

  3. No Access

    Article

    Low-temperature atomic-level trimming on Ge interfused surface for gate-all-around Si nanosheets transistors

    In order to effectively remove the residual Ge atoms at the surface of channel and improve the interfacial characteristic of gate-all-around (GAA) Si nanosheet field effect transistors, a low-temperature atomi...

    Guan-Qiao Sang, Ren-Jie Jiang, Yan-Zhao Wei, Qing-Kun Li, Mei-He Zhang in Rare Metals (2024)

  4. Article

    Open Access

    Maternal diseases and congenital anomalies of the kidney and urinary tract in offspring: a cohort study

    Congenital anomalies of the kidneys and urinary tract (CAKUT) are the most common cause of prenatally diagnosed developmental malformation. This study aimed to assess the relationship between maternal diseases...

    Qiang Ma, Ya-Qi Li, Qing-Tang Meng, Bo Yang, Hai-Tao Zhang in World Journal of Pediatrics (2024)

  5. Article

    Open Access

    Exploring the ecological security evaluation of water resources in the Yangtze River Basin under the background of ecological sustainable development

    The Yangtze River (hereafter referred to as the YZR), the largest river in China, is of paramount importance for ensuring water resource security. The Yangtze River Basin (hereafter referred to as the YRB) is ...

    Jie-Rong Zhou, **ao-Qing Li, **n Yu, Tian-Cheng Zhao, Wen-** Ruan in Scientific Reports (2024)

  6. Article

    Open Access

    Tamm-cavity terahertz detector

    Efficiently fabricating a cavity that can achieve strong interactions between terahertz waves and matter would allow researchers to exploit the intrinsic properties due to the long wavelength in the terahertz ...

    Xuecou Tu, Yichen Zhang, Shuyu Zhou, Wen**g Tang, Xu Yan in Nature Communications (2024)

  7. No Access

    Article

    Biocatalytic desymmetrization for synthesis of chiral enones using flavoenzymes

    Efficient methods for achieving desaturation of carbonyl compounds are highly sought after in organic chemistry. In contrast to synthetic approaches, enzymatic desaturation systems offer the potential to enhan...

    Qing-Qing Zeng, Qian-Yi Zhou, Carla Calvó-Tusell, Shuang-Yu Dai in Nature Synthesis (2024)

  8. Article

    Open Access

    PEX3 promotes regenerative repair after myocardial injury in mice through facilitating plasma membrane localization of ITGB3

    The peroxisome is a versatile organelle that performs diverse metabolic functions. PEX3, a critical regulator of the peroxisome, participates in various biological processes associated with the peroxisome. Whe...

    Jia-Teng Sun, Zi-Mu Wang, Liu-Hua Zhou, Tong-Tong Yang, Di Zhao in Communications Biology (2024)

  9. No Access

    Article

    Gliclazide Ameliorates Neuronal Injury by Attenuating Oxidative Stress in D-gal-Induced Senescent Cells and Aging Mice

    Enhancement of oxidative stress and resultant neuronal injury play important roles in initiating cognitive impairment during the aging process. Thus, attenuating oxidative injury is regarded as a profitable th...

    Deng-Pan Wu, Wen Yi, Yuan-Dan Zhao, Yan-Su Wei, Ling-Ling Liu in Molecular Neurobiology (2024)

  10. No Access

    Article

    Biosafety assessments of hexafluoropropylene trimer derivative as a fluorinated cooling fluid for electronics

    The Internet Data Center (IDC) is one of the most important infrastructures in the field of information technology. The cooling system for heat dissipation of IDC is indispensable due to it generates a large a...

    Yi-Tong Zhou, Pei-Jie Zhang, Shu-** Wang, Chang-Hao Li in Toxicological Research (2024)

  11. No Access

    Article

    Improvement of impact properties of Al–Si–Mg alloy via solution treatment and joint modification with Sr and La

    An effort to obtain superior impact properties for Al-7Si-0.35 Mg alloy is presented, where modification with 0.02 wt% Sr and 0.1 wt% La as well as solution treatment was jointly employed. The samples were sol...

    **ong-Ling Zheng, Shao-**ang Li, Jia-Le Ma, Qing-Yan Xu, Hai-Dong Zhao in Rare Metals (2024)

  12. Article

    Open Access

    PANX1-mediated ATP release confers FAM3A’s suppression effects on hepatic gluconeogenesis and lipogenesis

    Extracellular adenosine triphosphate (ATP) is an important signal molecule. In previous studies, intensive research had revealed the crucial roles of family with sequence similarity 3 member A (FAM3A) in contr...

    Cheng-Qing Hu, Tao Hou, Rui **ang, **n Li, **g Li in Military Medical Research (2024)

  13. No Access

    Article

    Plasma Ionomic Profile and Interaction Patterns in Coronary Artery Disease Patients

    Humans are exposed to various chemical elements that have been associated with the development and progression of diseases such as coronary artery disease (CAD). Unlike previous research, we employed a multi-e...

    Qing-Qing Zhao, **an-Long Shu, Zhen Yuan, Qian Gao in Biological Trace Element Research (2024)

  14. Article

    Open Access

    Correction: Gut microbiota-derived propionate mediates the neuroprotective effect of osteocalcin in a mouse model of Parkinson’s disease

    Yan-fang Hou, Chang Shan, Si-yue Zhuang, Qian-qian Zhuang, Arijit Ghosh in Microbiome (2024)

  15. Article

    Open Access

    PJA1-mediated suppression of pyroptosis as a driver of docetaxel resistance in nasopharyngeal carcinoma

    Chemoresistance is a main reason for treatment failure in patients with nasopharyngeal carcinoma, but the exact regulatory mechanism underlying chemoresistance in nasopharyngeal carcinoma remains to be elucida...

    Sheng-Yan Huang, Sha Gong, Yin Zhao, Ming-Liang Ye, Jun-Yan Li in Nature Communications (2024)

  16. No Access

    Article

    Two-dimensional metallic CoTe2 flakes for electrocatalytic hydrogen evolution

    Two-dimensional (2D) metallic 1T-CoTe2 has attracted considerable attention due to its fascinating physical properties and promising applications in electronics and catalysis. However, the production of high-qual...

    Yu-Qing Zhao, Qian Liu, Bo-Jian Zhou, Guang Yang, Shao-Long Jiang in Rare Metals (2024)

  17. No Access

    Article

    A novel dual-signal output strategy for POCT of CEA based on a smartphone electrochemical aptasensing platform

    A smartphone-based electrochemical aptasensing platform was developed for the point-of-care testing (POCT) of carcinoembryonic antigen (CEA) based on the ferrocene (Fc) and PdPt@PCN-224 dual-signal labeled st...

    Shan-Shan Shi, **ao-Jian Li, Rong-Na Ma, Lei Shang, Wei Zhang in Microchimica Acta (2024)

  18. Article

    Open Access

    Radiomic analysis based on magnetic resonance imaging for the prediction of VEGF expression in hepatocellular carcinoma patients

    The purpose of this study was to investigate the ability of radiomic characteristics of magnetic resonance images to predict vascular endothelial growth factor (VEGF) expression in hepatocellular carcinoma (HC...

    Cui Yang, Ze-Ming Zhang, Zhang-** Zhao, Zhi-Qing Wang, **g Zheng in Abdominal Radiology (2024)

  19. Article

    Open Access

    Mediating roles of activities of daily living and depression on the relationship between sleep quality and health-related quality of life

    This study aimed to explore the mediating effects of ADL and depression on the relationship between sleep quality and HRQOL among older people in rural China, while also exploring the moderating impact of lone...

    **ao-Qing Ren, Gong-Ming Zhao, Shuo-Wen Fang, Ling-Feng Xu in Scientific Reports (2024)

  20. No Access

    Article

    Mendelian randomization evidence for the causal effect of mental well-being on healthy aging

    Mental well-being relates to multitudinous lifestyle behaviours and morbidities and underpins healthy aging. Thus far, causal evidence on whether and in what pattern mental well-being impacts healthy aging and...

    Chao-Jie Ye, Dong Liu, Ming-Ling Chen, Li-Jie Kong, Chun Dou in Nature Human Behaviour (2024)

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