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First international conference of China on anatomical sciences
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Phase I and pharmacokinetic study of oral thalidomide in patients with advanced hepatocellular carcinoma
Purpose: To evaluate the dose-limiting toxicities (DLT), maximum tolerated dose (MTD), and pharmacokinetics of thalidomide in patients with advanced hepatocellular carcinoma (HCC). Methods: Patients with advanced...
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Morphine and Heroin Differentially Modulate In Vivo Hippocampal LTP in Opiate-Dependent Rat
Addictive drugs have been shown to severely influence many neuronal functions, which are considered as the underlying mechanisms for physiological and psychological dependences. We previously showed that in vivo ...
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Open AccessInteraction of δ-opioid receptor with membrane transporters: Possible mechanisms in pain suppression by acupuncture
研究阿片受体与神经递质转运蛋白和钠钾泵在针刺镇痛中的可能机制。
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Hypoxic tissues are associated with microvessel density following brain ischemia–reperfusion
Hypoxic tissue has been observed in the surrounding areas of the ischemic core following cerebral infarction. The underlying mechanisms for this potentially reversible ischemic region remain to be determined. ...
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A randomized, single-blind comparison of the efficacy and tolerability of hyaluronate acid and meloxicam in adult patients with Kashin–Beck disease of the knee
The aim of this study was to prospectively evaluate the efficacy and tolerability of hyaluronic acid (HA) and meloxicam for the treatment of knee pain due to Kashin–Beck disease (KBD). A total of 162 patients ...
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Decreased serum level of IL-21 in new-onset systemic lupus erythematosus patients
This study aims to investigate the serum IL-21 levels in systemic lupus erythematosus (SLE) and its relations with clinical and laboratory features. Fifty-seven patients with SLE and 30 healthy volunteers were...
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The effect of TGF-β1 polymorphism on systemic sclerosis: a systematic review and pooled analysis of available literature
Transforming growth factor-β1 (TGF-β1) plays an important role in the pathogenesis of systemic sclerosis (SSc). To investigate whether TGF-β1 gene promoter polymorphisms were associated with the susceptibility...
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Dietary fiber intake and risk of renal cell carcinoma: evidence from a meta-analysis
The aim of this study was to investigate the possible relationships between dietary fiber intake and risk of renal cell carcinoma (RCC). Electronic databases including MEDLINE, EMBASE and Web of Science were s...
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Intractable occipital lobe epilepsy: clinical characteristics, surgical treatment, and a systematic review of the literature
We reported our experience in the surgical treatment of a relatively large cohort of patients with occipital lobe epilepsy (OLE). We also carried out a systematic review of the literature on OLE.
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Open AccessScreening for pulmonary tuberculosis in type 2 diabetes elderly: a cross-sectional study in a community hospital
Tuberculosis is one of the major infectious diseases in Taiwan. It has an especially high prevalence in diabetes patients, in whom it is usually asymptomatic and are more likely to result in drug-resistant tub...
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Dan-gua Fang (丹瓜方) improves glycolipid metabolic disorders by promoting hepatic adenosine 5′-monophosphate activated protein kinase expression in diabetic Goto-Kakizaki rats
To investigate the effect of Dan-gua Fang (丹瓜方) on adenosine 5′-monophosphate (AMP) activated protein kinase (AMPK) α expression in liver and subsequent improvement of glucose and lipid metabolism.
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Open AccessQuantitative evaluation of the immunodeficiency of a mouse strain by tumor engraftments
The mouse is an organism that is widely used as a mammalian model for studying human physiology or disease, and the development of immunodeficient mice has provided a valuable tool for basic and applied human ...
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The EQ-5D-5L index score is more discriminative than the EQ-5D-3L index score in diabetes patients
To compare the discriminative power of the index scores of EQ-5D-5L (5L) and EQ-5D-3L (3L) in diabetes patients in China.
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Open AccessEffect of outdoor activity on myopia onset and progression in school-aged children in northeast china: the sujiatun eye care study
Due to its high prevalence and associated sight-threatening pathologies, myopia has emerged as a major health issue in East Asia. The purpose was to test the impact on myopia development of a school-based inte...
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Open AccessElectro-acupuncture decreases 5-HT, CGRP and increases NPY in the brain-gut axis in two rat models of Diarrhea-predominant irritable bowel syndrome(D-IBS)
To examine whether electro-acupuncture (EA) could decrease 5-hydroxytryptamine (5-HT) and calcitonin gene-related peptide (CGRP), and increase neuro-peptide Y (NPY) in the brain-gut axis (BGA) in D-IBS using rat ...
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Keyhole epilepsy surgery: corticoamygdalohippocampectomy for mesial temporal sclerosis
Surgical approaches for medically refractory mesial temporal lobe epilepsy (MTLE) that previously have been reported include anterior temporal lobectomy (ATL), transcortical selective amygdalohippocampectomy, ...
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Open AccessAligning to the sample-specific reference sequence to optimize the accuracy of next-generation sequencing analysis for hepatitis B virus
Hepatitis B virus (HBV) quasispecies are crucial in the pathogenesis of chronic liver disease. Next-generation sequencing (NGS) is powerful for identifying viral quasispecies. To improve map** quality and si...
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Increased carotid intima-media thickness in rheumatoid arthritis: an update meta-analysis
This study aims to derive a more precise estimation on carotid intima-media thickness (CIMT) level in patients with rheumatoid arthritis (RA) and related factors. Studies published from January 1, 1982 to Dece...
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Open AccessProceedings of the 7th Biannual International Symposium on Nasopharyngeal Carcinoma 2015
A1 Hope and despair in the current treatment of nasopharyngeal cancer