1,188 Result(s)
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**-jun Qian
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Open AccessA case of Ph+ acute lymphoblastic leukemia and EGFR mutant lung adenocarcinoma synchronous overlap: may one TKI drug solve two diseases?
Philadelphia chromosome positive (Ph+) acute lymphoblastic leukemia (ALL) refers to ALL patients with t(9;22) cytogenetic abnormalities, accounting for about 25% of ALL. Lung adenocarcinoma (LUAD) is the most com...
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Experimental study on the mechanical properties of desert sand improved by the combination of additives and bio-cement
Bio-cement is a green and energy-saving building material that has attracted much attention in the field of ecological environment and geotechnical engineering in recent years. The aim of this study is to inve...
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Notopterygium Incisum Extract Promotes Apoptosis by Preventing the Degradation of BIM in Colorectal Cancer
Colorectal cancer (CRC), a prevalent malignancy worldwide, has prompted extensive research into anticancer drugs. Traditional Chinese medicinal materials offer promising avenues for cancer management due to th...
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Salvage haploidentical transplantation for graft failure after first haploidentical allogeneic stem cell transplantation: an updated experience
Graft failure is a fatal complication following allogeneic stem cell transplantation where a second transplantation is usually required for salvage. However, there are no recommended regimens for second transp...
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Open AccessA pan-KRAS degrader for the treatment of KRAS-mutant cancers
KRAS mutations are highly prevalent in a wide range of lethal cancers, and these mutant forms of KRAS play a crucial role in driving cancer progression and conferring resistance to treatment. While there have bee...
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Diversified deep hierarchical kernel ensemble regression
Deep ensemble learning models that combine multiple independent deep learning models with multi-layer processing architectures have proven to be effective techniques for improving the accuracy and robustness o...
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Open AccessRelationship of urinary glyphosate concentrations with glycosylated hemoglobin and diabetes in US adults: a cross-sectional study
Glyphosate is a commonly used herbicide worldwide and is purportedly associated with multiple health effects. Research assessing the association of glyphosate concentrations with glycosylated hemoglobin (HbA1c...
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Open AccessInhibiting the CB1 receptor in CIH-induced animal model alleviates colon injury
Obstructive sleep apnea (OSA) can lead to intestinal injury, endotoxemia, and disturbance of intestinal flora. Additionally, as a crucial component of the endocannabinoid system, some studies have demonstrated...
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Open AccessGenome-wide enhancer RNA profiling adds molecular links between genetic variation and human cancers
Dysregulation of enhancer transcription occurs in multiple cancers. Enhancer RNAs (eRNAs) are transcribed products from enhancers that play critical roles in transcriptional control. Characterizing the genetic...
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Binder-induced ultrafast PF6−-intercalation toward a high-voltage, high-power and long-cycling zinc–graphite dual-ion battery
Metallic zinc is an ideal anode material owing to its high theoretical capacity (819 mAh·g−1), eco-friendliness, low cost and high safety, which have driven fast development of Zn-ion batteries (ZIBs). However, t...
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Effects of nanographene oxide on adipose-derived stem cell cryopreservation
Cryoinjury mitigation is key in cell cryopreservation. Here, we aimed to assess the effectiveness of nanographene oxide (nano-GO) for improving cryoprotectant agents (CPAs) in human adipose stem cell (hADSC) c...
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Interfacing biosynthetic CdS with engineered Rhodopseudomonas palustris for efficient visible light-driven CO2–CH4 conversion
Engineered photosynthetic bacterium Rhodo-pseudomonas palustris is excellent at one-step CO2 biomethanation and can use near-infrared light sources, overcoming the limitations of conventional photosynthetic syste...
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Desloratadine ameliorates paclitaxel-induced peripheral neuropathy and hypersensitivity reactions in mice
Paclitaxel (PTX) serves as a primary chemotherapy agent against diverse solid tumors including breast cancer, lung cancer, head and neck cancer and ovarian cancer, having severe adverse effects including PTX-i...
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Open AccessCOVID-19 was associated with the complications after allogeneic hematopoietic stem cell transplantation
We aimed to identify the severity and duration of COVID-19 infection on complications after allo-HSCT. Enrolled 179 hospitalized patients with COVID-19 were categorized into long-term infection (> 18 days, n = 90...
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m6A demethylation of FOSL1 mRNA protects hepatoma cells against necrosis under glucose deprivation
Stress-adaptive mechanisms enabling cancer cells to survive under glucose deprivation remain elusive. N6-methyladenosine (m6A) modification plays important roles in determining cancer cell fate and cellular stres...
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Open AccessStretchable phosphorescent polymers by multiphase engineering
Stretchable phosphorescence materials potentially enable applications in diverse advanced fields in wearable electronics. However, achieving room-temperature phosphorescence materials simultaneously featuring ...
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Open AccessSignal enhancement ratio of multi-phase contrast-enhanced MRI: an imaging biomarker for survival in pancreatic adenocarcinoma
To evaluate signal enhancement ratio (SER) for tissue characterization and prognosis stratification in pancreatic adenocarcinoma (PDAC), with quantitative histopathological analysis (QHA) as the reference stan...
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Open AccessEstablishment of an automatic diagnosis system for corneal endothelium diseases using artificial intelligence
To use artificial intelligence to establish an automatic diagnosis system for corneal endothelium diseases (CEDs).
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Open AccessPeriodontal disease increases the severity of chronic obstructive pulmonary disease: a Mendelian randomization study
Recent research suggests that periodontitis can increase the risk of chronic obstructive pulmonary disease (COPD). In this study, we performed two-sample Mendelian randomization (MR) and investigated the causa...
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Chemical Constituents from the Roots of Cynanchum atratum
