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    Article

    St. John’s Wort Modulates the Toxicities and Pharmacokinetics of CPT-11 (Irinotecan) in Rats

    CPT-11 is a DNA topoisomerase I inhibitor for the therapy of colorectal cancer, whereas St. John’s Wort (Hypericum perforatum, SJW) is a widely used herbal anti-depressant. This study aimed to investigate the eff...

    Ze** Hu, **aoxia Yang, Paul Chi-Liu Ho, Eli Chan in Pharmaceutical Research (2005)

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    Human Multidrug Resistance Associated Protein 4 Confers Resistance to Camptothecins

    The multidrug resistance associated protein (MRP) 4 is a member of the adenosine triphosphate (ATP)-binding cassette transporter family. Camptothecins (CPTs) have shown substantial anticancer activity against ...

    Quan Tian, **g Zhang, Theresa May Chin Tan, Eli Chan, Wei Duan in Pharmaceutical Research (2005)

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    Spatial Filtering Improves EMG Classification Accuracy Following Targeted Muscle Reinnervation

    The combination of targeted muscle reinnervation (TMR) and pattern classification of electromyography (EMG) has shown great promise for multifunctional myoelectric prosthesis control. In this study, we hypothe...

    He Huang, ** Zhou, Guanglin Li, Todd Kuiken in Annals of Biomedical Engineering (2009)