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Article
St. John’s Wort Modulates the Toxicities and Pharmacokinetics of CPT-11 (Irinotecan) in Rats
CPT-11 is a DNA topoisomerase I inhibitor for the therapy of colorectal cancer, whereas St. John’s Wort (Hypericum perforatum, SJW) is a widely used herbal anti-depressant. This study aimed to investigate the eff...
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Article
Human Multidrug Resistance Associated Protein 4 Confers Resistance to Camptothecins
The multidrug resistance associated protein (MRP) 4 is a member of the adenosine triphosphate (ATP)-binding cassette transporter family. Camptothecins (CPTs) have shown substantial anticancer activity against ...
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Article
Detection of antibody to hepatitis delta virus in human serum by double antigen sandwich ELISA
A simple rapid detection of antibody to hepatitis delta virus (anti-HDV) in human serum was developed by using double antigen sandwich ELISA. HDV gene fragment encoding HDAg was isolated from a Chinese patient...
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Article
Spatial Filtering Improves EMG Classification Accuracy Following Targeted Muscle Reinnervation
The combination of targeted muscle reinnervation (TMR) and pattern classification of electromyography (EMG) has shown great promise for multifunctional myoelectric prosthesis control. In this study, we hypothe...
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Article
Identification of a novel torque teno mini virus in cerebrospinal fluid from a child with encephalitis
Anelloviruses are single-strand circular DNA viruses and ubiquitous within the human population. Although there is no direct evidence, many studies have suggested the anelloviruses may be associated with a var...
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Article
Serological Evidence of Bat SARS-Related Coronavirus Infection in Humans, China