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  1. No Access

    Article

    A 300 kilobase interval genetic map of rice including 883 expressed sequences

    We have constructed a high resolution rice genetic map containing 1,383 DNA markers at an average interval of 300 kilobases (kb). The markers, distributed along 1,575 cM on 12 linkage groups, comprise 883 cDNA...

    N. Kurata, Y. Nagamura, K. Yamamoto, Y. Harushima, N. Sue, J. Wu in Nature Genetics (1994)

  2. No Access

    Article

    Distinct molecular mechanisms and divergent endocytotic pathways of AMPA receptor internalization

    Internalization of postsynaptic AMPA receptors depresses excitatory transmission, but the underlying dynamics and mechanisms of this process are unclear. Using immunofluorescence and surface biotinylation, we ...

    Jerry W. Lin, William Ju, Kelly Foster, Sang Hyoung Lee in Nature Neuroscience (2000)

  3. No Access

    Article

    Evolutionary and biomedical implications of a Schistosoma japonicum complementary DNA resource

    Schistosoma japonicum causes schistosomiasis in humans and livestock in the Asia-Pacific region. Knowledge of the genome of this parasite should improve understanding of schistosome-host interactions, biomedical ...

    Wei Hu, Qing Yan, Da-Kang Shen, Feng Liu, Zhi-Dong Zhu, Huai-Dong Song in Nature Genetics (2003)

  4. No Access

    Article

    Focal adhesion kinase in netrin-1 signaling

    Netrins are a family of secreted molecules that are important for axonal outgrowth and guidance in the develo** nervous system. However, the signaling mechanisms that lie immediately downstream of netrin rec...

    **u-rong Ren, Guo-li Ming, Yi **e, Yan Hong, Dong-mei Sun in Nature Neuroscience (2004)

  5. No Access

    Article

    A rice quantitative trait locus for salt tolerance encodes a sodium transporter

    Many important agronomic traits in crop plants, including stress tolerance, are complex traits controlled by quantitative trait loci (QTLs). Isolation of these QTLs holds great promise to improve world agricul...

    Zhong-Hai Ren, Ji-** Gao, Le-Gong Li, **u-Ling Cai, Wei Huang in Nature Genetics (2005)

  6. No Access

    Article

    RAPD analysis of genetic diversity and population genetic structure of Stipa krylovii reshov. in Inner Mongolia steppe

    Random amplified polymorphic DNA (RAPD) analysis was used to characterize the genetic diversity and population genetic structure of Stipa krylovii populations in Inner Mongolia steppe of North China. Thirteen 10-...

    J. L. Wang, N. X. Zhao, Y. B. Gai, F. Lin, A. Z. Ren in Russian Journal of Genetics (2006)

  7. No Access

    Article

    Crystal structure of the extracellular domain of nAChR α1 bound to α-bungarotoxin at 1.94 Å resolution

    We determined the crystal structure of the extracellular domain of the mouse nicotinic acetylcholine receptor (nAChR) α1 subunit bound to α-bungarotoxin at 1.94 Å resolution. This structure is the first atomic...

    Cosma D Dellisanti, Yun Yao, James C Stroud, Zuo-Zhong Wang in Nature Neuroscience (2007)

  8. No Access

    Article

    Specific requirement of NMDA receptors for long-term memory consolidation in Drosophila ellipsoid body

    In humans and many other animals, memory consolidation occurs through multiple temporal phases and usually involves more than one neuroanatomical brain system. Genetic dissection of Pavlovian olfactory learnin...

    Chia-Lin Wu, Shouzhen **a, Tsai-Feng Fu, Huaien Wang, Ying-Hsiu Chen in Nature Neuroscience (2007)

  9. No Access

    Article

    Fine map** of regulatory loci for mammalian gene expression using radiation hybrids

    We mapped regulatory loci for nearly all protein-coding genes in mammals using comparative genomic hybridization and expression array measurements from a panel of mouse–hamster radiation hybrid cell lines. The...

    Christopher C Park, Sangtae Ahn, Joshua S Bloom, Andy Lin in Nature Genetics (2008)

  10. No Access

    Article

    Control of rice grain-filling and yield by a gene with a potential signature of domestication

    Zuhua He and colleagues identify the gene underlying a quantitative trait locus for grain-filling in rice, which contributes to grain weight. The gene, GIF1, encodes a protein with cell-wall invertase activity an...

    Ertao Wang, Jianjun Wang, Xudong Zhu, Wei Hao, Linyou Wang, Qun Li in Nature Genetics (2008)

  11. No Access

    Article

    Psoriasis genome-wide association study identifies susceptibility variants within LCE gene cluster at 1q21

    Xuejun Zhang and colleagues report a genome-wide association and replication studies for psoriasis, conducted in Chinese populations. They confirm previous associations in MHC and IL12B to psoriasis susceptibilit...

    Xue-Jun Zhang, Wei Huang, Sen Yang, Liang-Dan Sun, Feng-Yu Zhang in Nature Genetics (2009)

  12. No Access

    Article

    Genome-wide association study in a Chinese Han population identifies nine new susceptibility loci for systemic lupus erythematosus

    Xuejun Zhang and colleagues report results of a genome-wide association study of systemic lupus erythematosus (SLE) in a Chinese Han population. Their work identifies nine new SLE susceptibility loci and revea...

    Jian-Wen Han, Hou-Feng Zheng, Yong Cui, Liang-Dan Sun, Dong-Qing Ye in Nature Genetics (2009)

  13. No Access

    Article

    The genome of the cucumber, Cucumis sativus L.

    Jun Wang and colleagues report the genome sequence of the cucumber. The cucumber genome is the seventh plant genome sequence to be reported and was assembled with a combination of traditional Sanger and next-g...

    Sanwen Huang, Ruiqiang Li, Zhonghua Zhang, Li Li, **ngfang Gu, Wei Fan in Nature Genetics (2009)

  14. No Access

    Article

    Genome-wide association study of esophageal squamous cell carcinoma in Chinese subjects identifies a susceptibility locus at PLCE1

    Li Dong Wang and colleagues report a genome wide association study for esophageal squamous cell carcinoma in the Chinese population. They identify two risk loci at PLCE1 and C20orf54.

    Li-Dong Wang, Fu-You Zhou, Xue-Min Li, Liang-Dan Sun, **n Song, Yan ** in Nature Genetics (2010)

  15. No Access

    Article

    A shared susceptibility locus in PLCE1 at 10q23 for gastric adenocarcinoma and esophageal squamous cell carcinoma

    Christian Abnet and colleagues report genome-wide association studies for gastric adenocarcinoma and esophageal squamous cell carcinoma in a Chinese population. They identified a new shared risk locus in the PLCE...

    Christian C Abnet, Neal D Freedman, Nan Hu, Zhaoming Wang, Kai Yu in Nature Genetics (2010)

  16. No Access

    Article

    Association analyses identify six new psoriasis susceptibility loci in the Chinese population

    Xue-Jun Zhang and colleagues report genome-wide association analyses identifying six new susceptibility loci in the Chinese population.

    Liang-Dan Sun, Hui Cheng, Zai-**ng Wang, An-** Zhang, Pei-Guang Wang in Nature Genetics (2010)

  17. No Access

    Article

    The developmental dynamics of the maize leaf transcriptome

    Thomas Brutnell and colleagues report RNA-Seq analysis of the maize leaf transcriptome during stages of leaf development. They identify dynamic changes in gene expression during the progression of leaf develop...

    **hua Li, Lalit Ponnala, Neeru Gandotra, Lin Wang, Yaqing Si in Nature Genetics (2010)

  18. No Access

    Article

    Drosophila Piwi functions in Hsp90-mediated suppression of phenotypic variation

    Haifan Lin and colleagues report the identification in Drosophila of a protein complex composed of Hsp90 Piwi, and the Hsp70/Hsp90 Organizing Protein Homolog (Hop) and demonstrate the function of this complex in ...

    Vamsi K Gangaraju, Hang Yin, Molly M Weiner, Jianquan Wang, **ao A Huang in Nature Genetics (2011)

  19. No Access

    Article

    Genome-wide association study identifies two new susceptibility loci for atopic dermatitis in the Chinese Han population

    Xue-Jun Zhang, Zhi-Rong Yao and colleagues report a genome-wide association study for atopic dermatitis in the Chinese Han population. They identified two new susceptibility loci at 5q22 and 20q13.

    Liang-Dan Sun, Feng-Li **ao, Yang Li, Wen-Ming Zhou, Hua-Yang Tang in Nature Genetics (2011)

  20. No Access

    Article

    Extensive and coordinated transcription of noncoding RNAs within cell-cycle promoters

    David Wong, Howard Chang and colleagues report the identification of long noncoding RNAs transcribed from the promoters of cell cycle genes. Many of these RNAs have periodic expression during the cell cycle an...

    Tiffany Hung, Yulei Wang, Michael F Lin, Ashley K Koegel, Yojiro Kotake in Nature Genetics (2011)

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