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1,797 Result(s)
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Article
Impact of Presarcopenic Dysphagia on 1-Year Mortality After Videofluoroscopic Swallowing Study in Patients with Cancer
Sarcopenic dysphagia is the term for swallowing difficulty associated with loss of mass, strength, and physical performance, which leads to increased pharyngeal residues. Unlike sarcopenia, presarcopenia is ch...
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Open AccessLong-term outcomes of neoadjuvant trastuzumab emtansine + pertuzumab (T-DM1 + P) and docetaxel + carboplatin + trastuzumab + pertuzumab (TCbHP) for HER2-positive primary breast cancer: results of the randomized phase 2 JBCRG20 study (Neo-peaks)
The randomized phase 2 Neo-peaks study examined usefulness of neoadjuvant trastuzumab emtansine + pertuzumab (T-DM1 + P) following docetaxel + carboplatin + trastuzumab + pertuzumab (TCbHP) as compared with th...
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Open AccessNonlinear association between PD-L1 expression levels and the risk of postoperative recurrence in non-small cell lung cancer
Accurate prediction of postoperative recurrence is important for optimizing the treatment strategies for non-small cell lung cancer (NSCLC). Previous studies identified the PD-L1 expression in NSCLC as a risk ...
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Open AccessCorrection: The Japanese Breast Cancer Society Clinical Practice Guidelines for Breast Cancer, 2022 Edition: changes from the 2018 edition and general statements on breast cancer treatment
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Open AccessUrine oxygenation predicts COVID-19 risk
Since February, 2023, the omicron variant has accounted for essentially all new coronavirus infections in Japan. If future infections involve mutant strains with the same level of infectivity and virulence as ...
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Circulating Exosomal MicroRNA Signature Predicts Peritoneal Metastasis in Patients with Advanced Gastric Cancer
Despite a radical operation, about half of gastric cancer (GC) patients with advanced GC experience peritoneal metastasis (PM), and the patients with PM have a poor prognosis. However, because staging laparosc...
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Open AccessA newly identified gene Ahed plays essential roles in murine haematopoiesis
The development of haematopoiesis involves the coordinated action of numerous genes, some of which are implicated in haematological malignancies. However, the biological function of many genes remains elusive ...
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Open AccessPartial cardiopulmonary bypass through left thoracotomy for coarctation repair in children
A left thoracotomy approach is anatomically appropriate for childhood aortic coarctation; however, the pediatric femoral arteriovenous diameters are too small for cardiopulmonary bypass cannulation. We aimed t...
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Article
Prognostic impact of the combination of p16INK4a, p21 and Immunoscore in rectal cancer
The association between p16INK4a and p21, a marker of cellular senescence, and the Immunoscore, an immunological prognostic indicator, in rectal cancer patients undergoing curative surgery were investigated.
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Open AccessTrastuzumab deruxtecan versus treatment of physician’s choice in previously treated Asian patients with HER2-low unresectable/metastatic breast cancer: subgroup analysis of the DESTINY-Breast04 study
In the global phase 3 DESTINY-Breast04 study (NCT03734029), the anti-human epidermal growth factor 2 (HER2) antibody–drug conjugate trastuzumab deruxtecan (T-DXd) demonstrated a statistically significant impro...
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Open AccessTrends in Anti-Influenza Drug Prescription and Adverse Drug Reaction Reporting After the Lifting of Oseltamivir Prescribing Restrictions in Pediatric Outpatients: An Ecological Study Using the MDV Analyzer® And the Japanese Adverse Drug Event Report Database
Abnormal behavior after oseltamivir administration has been reported in the media; in 2007, the package insert for oseltamivir phosphate was revised to restrict its administration to individuals aged over 10 y...
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Article
Prognostic Significance of Sarcopenia and Systemic Inflammatory Markers in Biliary Tract Cancer: A Retrospective Cohort Study
To evaluate the prognostic significance of sarcopenia and systemic inflammatory markers in patients with surgically resected biliary tract cancer (BTC).
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Article
High versus low chloride load in adult hyperglycemic emergencies with acute kidney injury: a multicenter retrospective cohort study
Hyperglycemic emergencies frequently lead to acute kidney injury (AKI) and require treatment with large amount of intravenous fluids. However, the effects of chloride loading on this population have not yet be...
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Open AccessBlue light irradiation inhibits the M2 polarization of the cancer-associated macrophages in colon cancer
Recent studies have shown that blue light-emitting diode (LED) light has anti-tumor effects, suggesting the possibility of using visible light in cancer therapy. However, the effects of blue light irradiation ...
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Article
Open AccessPhotoinduced dynamics during electronic transfer from narrow to wide bandgap layers in one-dimensional heterostructured materials
Electron transfer is a fundamental energy conversion process widely present in synthetic, industrial, and natural systems. Understanding the electron transfer process is important to exploit the uniqueness of ...
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Article
Open AccessLayer-Wise External Attention by Well-Localized Attention Map for Efficient Deep Anomaly Detection
The external attention mechanism offers a promising approach to enhance image anomaly detection (Hayakawa et al., in: IMPROVE, pp. 100-–110, 2023). Nevertheless, the effectiveness of this method is contingent ...
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Open AccessDynamic movement of the Golgi unit and its glycosylation enzyme zones
Knowledge on the distribution and dynamics of glycosylation enzymes in the Golgi is essential for better understanding this modification. Here, using a combination of CRISPR/Cas9 knockin technology and super-r...
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Article
Open AccessHigher order exchange driven noncoplanar magnetic state and large anomalous Hall effects in electron doped kagome magnet Mn3Sn
Owing to geometrical frustration in the kagome lattice, Mn3Sn displays a 120° in-plane triangular antiferromagnetic order, a manifestation of exchange interaction within the Heisenberg model. Here, we show the fo...
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Article
All-to-All Data Exchange Method for MANET in Congestion Environment
Mobile Ad-hoc Network (MANET) are expected to be a means of communication for disaster victim support systems and information distribution systems at event sites where it is challenging to use existing infrast...
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Open AccessJapanese tort-case dataset for rationale-supported legal judgment prediction
This paper presents the first dataset for Japanese Legal Judgment Prediction (LJP), the Japanese Tort-case Dataset (JTD), which features two tasks: tort prediction and its rationale extraction. The rationale e...