110 Result(s)
within
** Lu Li
Life Sciences
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Article
Open AccessComplete chloroplast genome structural characterization of two Aerides (Orchidaceae) species with a focus on phylogenetic position of Aerides flabellata
The disputed phylogenetic position of Aerides flabellata Rolfe ex Downie, due to morphological overlaps with related species, was investigated based on evidence of complete chloroplast (cp) genomes. The structura...
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Open AccessCharacterizing human postprandial metabolic response using multiway data analysis
Analysis of time-resolved postprandial metabolomics data can improve our understanding of the human metabolism by revealing similarities and differences in postprandial responses of individuals. Traditional da...
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A 217-year precipitation reconstruction in the Habahe area, **njiang, Northeast China
Evaluating long-term changes in precipitation resources is important for accurate hydrological evaluation and forecasting, water security and rational allocation of water resources. For this purpose in the **n...
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Short-term regulation of TSFM level does not alter amyloidogenesis and mitochondrial function in type-specific cells
Mitochondrial Ts translation elongation factor (TSFM) is an enzyme that catalyzes exchange of guanine nucleotides. By forming a complex with mitochondrial Tu translation elongation factor (TUFM), TSFM particip...
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Open AccessAnalyzing postprandial metabolomics data using multiway models: a simulation study
Analysis of time-resolved postprandial metabolomics data can improve the understanding of metabolic mechanisms, potentially revealing biomarkers for early diagnosis of metabolic diseases and advancing precisio...
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Nitric oxide and ion channels mediate l-cysteine-induced inhibition of colonic smooth muscle contraction
Previous studies have suggested that l-cysteine regulates gut motility through hydrogen sulfide. However, the mechanisms involved in the l-cysteine-induced response have not been extensively studied. This study a...
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Establishment and characterization of DPC-X4: a novel mixed-type ampullary cancer cell line
Mixed-type ampullary cancer is a distinct subtype of ampullary cancer that manifests a merging of the biological characteristics of both intestinal and pancreaticobiliary subtypes. The absence of established c...
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Open AccessAutophagy-modulating biomaterials: multifunctional weapons to promote tissue regeneration
Autophagy is a self-renewal mechanism that maintains homeostasis and can promote tissue regeneration by regulating inflammation, reducing oxidative stress and promoting cell differentiation. The interaction be...
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Open AccessThe small molecule raptinal can simultaneously induce apoptosis and inhibit PANX1 activity
Discovery of new small molecules that can activate distinct programmed cell death pathway is of significant interest as a research tool and for the development of novel therapeutics for pathological conditions...
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Develo** an efficient and visible prime editing system to restore tobacco 8-hydroxy-copalyl diphosphate gene for labdane diterpene Z-abienol biosynthesis
Prime editing (PE) is a versatile CRISPR-Cas based precise genome-editing platform widely used to introduce a range of possible base conversions in various organisms. However, no PE systems have been shown to ...
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Open AccessThe secreted peptide BATSP1 promotes thermogenesis in adipocytes
Although brown adipose tissue (BAT) has historically been viewed as a major site for energy dissipation through thermogenesis, its endocrine function has been increasingly recognized. However, the circulating ...
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Open AccessEffects of a novel ANLN E841K mutation associated with SRNS on podocytes and its mechanism
Steroid-resistant nephrotic syndrome (SRNS) is characterized by unrelieved proteinuria after an initial 4–8 weeks of glucocorticoid therapy. Genes in podocytes play an important role in causing SRNS.
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Effect of dietary protein, vitamin E, and vitamin C levels on the growth and gonad development of hybrid male abalone (Haliotis fulgens ♂ × H. discus hannai ♀) by the orthogonal array design
A natural feed of fresh seaweed and sixteen diets designed by L16 (43) orthogonal array were formulated to contain different levels of protein (200, 250, 300, and 350 g/kg), vitamin E (VE) (0, 0.1, 0.3, and 0.5 g...
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Open AccessHeme oxygenase 1 alleviates nonalcoholic steatohepatitis by suppressing hepatic ferroptosis
Heme oxygenase 1 (HO-1) has an influential but insufficiently investigated effect on ferroptosis, which is a novel form of programmed cell death and may play an effect on nonalcoholic steatohepatitis (NASH). H...
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Open AccessComplete chloroplast genome structural characterization of two Phalaenopsis (Orchidaceae) species and comparative analysis with their alliance
The taxonomy and infrageneric delimitation of Phalaenopsis Blume has been significantly disputed due to some overlap** morphological features between species related, which needed further evidence for clarifica...
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Open AccessIdentification of C2H2 zinc finger genes through genome-wide association study and functional analyses of LkZFPs in response to stresses in Larix kaempferi
C2H2 zinc finger proteins (C2H2-ZFPs), one of the largest transcription factors, play a variety of roles in plant development and growth as well as stress response. While, the evolutionary history and expressi...
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Open AccessA homozygous missense mutation in the fibroblast growth factor 5 gene is associated with the long-hair trait in Angora rabbits
Rabbits are well-domesticated animals. As a crucial economic animal, rabbit has been successfully bred into wool-use, meat-use and fur-use breeds. Hair length is one of the most economically important traits a...
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CSNK1D-mediated phosphorylation of HNRNPA2B1 induces miR-25-3p/miR-93-5p maturation to promote prostate cancer cell proliferation and migration through m6A-dependent manner
It has been reported that heterogeneous nuclear ribonucleoprotein A2/B1 (HNRNPA2B1) is highly expressed in prostate cancer (PCa) and associated with poor prognosis of patients with PCa. Nevertheless, the speci...
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The shadows hang over immunotherapy-neutrophil extracellular traps in cancer
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Open AccessHuman umbilical cord mesenchymal stem cell-derived TGFBI attenuates streptozotocin-induced type 1 diabetes mellitus by inhibiting T-cell proliferation
MSCs have been demonstrated to have a great benefit for type 1 diabetes mellitus (T1DM) due to their strong immunosuppressive and regenerative capacity. However, the comprehensive mechanism is still unclear. O...
