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Article
Open AccessInhibiting stromal Class I HDACs curbs pancreatic cancer progression
Oncogenic lesions in pancreatic ductal adenocarcinoma (PDAC) hijack the epigenetic machinery in stromal components to establish a desmoplastic and therapeutic resistant tumor microenvironment (TME). Here we id...
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Article
Open AccessA super-enhancer-regulated RNA-binding protein cascade drives pancreatic cancer
Pancreatic ductal adenocarcinoma (PDAC) is a lethal malignancy in need of new therapeutic options. Using unbiased analyses of super-enhancers (SEs) as sentinels of core genes involved in cell-specific function...
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Article
Open AccessMachine learning-derived gut microbiome signature predicts fatty liver disease in the presence of insulin resistance
A simple predictive biomarker for fatty liver disease is required for individuals with insulin resistance. Here, we developed a supervised machine learning-based classifier for fatty liver disease using fecal ...
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Article
Naphthalene-Diimide-Based Small Molecule Containing a Thienothiophene Linker for n-Type Organic Field-Effect Transistors
A naphthalene diimide (NDI)-based small molecule with a thienothiophene linker (NDI-TT-NDI) was synthesized for use as a semiconductor layer in solution-processable n-type organic field-effect transistors (OFE...
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Article
Control of temperature dependence of microbial time–temperature integrator (TTI) by microencapsulation of lactic acid bacteria into microbeads with different proportions of alginate
This study has been conducted to investigate the temperature dependence and mass transfer kinetics of a microbial time–temperature integrator (TTI) developed by using emulsification/internal ionotropic gelatio...
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Publisher Correction: Immune-evasive human islet-like organoids ameliorate diabetes
A Correction to this paper has been published: https://doi.org/10.1038/s41586-020-03109-3.
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Article
Immune-evasive human islet-like organoids ameliorate diabetes
Islets derived from stem cells hold promise as a therapy for insulin-dependent diabetes, but there remain challenges towards achieving this goal1–6. Here we generate human islet-like organoids (HILOs) from induce...
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Article
Open AccessA convergence broadcasting transmission of fixed 4K UHD and mobile HD services through a single terrestrial channel by employing FEF multiplexing technique in DVB-T2
Recently, a convergence broadcasting transmission for providing fixed 4K ultrahigh-definition (UHD) and mobile high-definition (HD) services through a single terrestrial channel is investigated by employing mu...
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Article
Open AccessA study of development of transmission systems for next-generation terrestrial 4 K UHD and HD convergence broadcasting
The worldwide transition from analog to digital broadcasting has now been completed, and the need to study next-generation standards for ultra-high-definition TV (UHDTV) broadcasting, as well as broadcasting a...
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Article
Open AccessCarrier frequency offset estimation method for 2 × 1 MISO TDS-OFDM systems
In time-domain synchronous (TDS)-orthogonal frequency division multiplexing (OFDM) systems, a pseudo noise (PN) sequence is inserted instead of the cyclic prefix. The PN sequence is used not only as a guard in...
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Article
Does the degree of experience for the tension-free vaginal tape procedure influence the results of the suprapubic arc sling procedure during the learning phase?
The object was to evaluate whether the degree of experience for the tension-free vaginal tape (TVT) procedures influenced the early results of the suprapubic arc (SPARC) sling procedure.
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Article
Significance of tension in tension-free mid-urethral sling procedures: a preliminary study
We report the results of the release and tape-shortening techniques in polypropylene pubovaginal slings. Of female patients who had undergone mid-urethral sling procedures [tension-free vaginal tape procedure ...
