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  1. Article

    Open Access

    Implication of lymph node staging in migration and different treatment strategies for stage T2N0M0 and T1N1M0 resected gastric cancer: a SEER population analysis

    The purpose of this study was to explore the differences between stage T2N0M0 and stage T1N1M0 gastric cancer (GC) and to identify the necessity of adjuvant treatment (AT) for these stages.

    Y. Wang, J. Zhang, S. Guo, Z. Dong, X. Meng… in Clinical and Translational Oncology (2019)

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  2. Article

    Open Access

    Targeting IL-2: an unexpected effect in treating immunological diseases

    Regulatory T cells (Treg) play a crucial role in maintaining immune homeostasis since Treg dysfunction in both animals and humans is associated with multi-organ autoimmune and inflammatory disease. While IL-2 ...

    Congxiu Ye, David Brand, Song G. Zheng in Signal Transduction and Targeted Therapy (2018)

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  3. Article

    Open Access

    SRGN-TGFβ2 regulatory loop confers invasion and metastasis in triple-negative breast cancer

    Patients with triple-negative breast cancers (TNBC) are at a high risk for a recurrent or metastatic disease, and the molecular mechanisms associated with this risk are unclear. Proteoglycan serglycin (SRGN) p...

    Z Zhang, Y Deng, G Zheng, X Jia, Y **ong, K Luo, Q Qiu, Ni Qiu, J Yin, M Lu… in Oncogenesis (2017)

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  4. No Access

    Article

    Comparison of clinicopathological features and prognosis of gastric cancer located in the lesser and greater curve

    Little is known about the features of gastric cancer located in the lesser and greater curve. This study aims to investigate the clinicopathological features and prognosis of gastric cancer located in the less...

    F. Feng, Y. Tian, M. Guo, S. Liu, G. Xu, Z. Liu… in Clinical and Translational Oncology (2017)

  5. No Access

    Article

    Cip2a promotes cell cycle progression in triple-negative breast cancer cells by regulating the expression and nuclear export of p27Kip1

    Triple-negative breast cancer (TNBC) is very aggressive and currently has no specific therapeutic targets; as a consequence, TNBC exhibits poor clinical outcome. In this study, we showed that cancerous inhibit...

    H Liu, H Qiu, Y Song, Y Liu, H Wang, M Lu, M Deng, Y Gu, J Yin, K Luo, Z Zhang… in Oncogene (2017)

  6. No Access

    Article

    Donor cell leukemia arising from clonal hematopoiesis after bone marrow transplantation

    L P Gondek, G Zheng, G Ghiaur, A E DeZern, W Matsui, S Yegnasubramanian… in Leukemia (2016)

  7. No Access

    Article

    TRM6/61 connects PKCα with translational control through tRNAiMet stabilization: impact on tumorigenesis

    Accumulating evidence suggests that changes of the protein synthesis machinery alter translation of specific mRNAs and participate in malignant transformation. Here we show that protein kinase C α (PKCα) inter...

    F Macari, Y El-houfi, G Boldina, H Xu, S Khoury-Hanna, J Ollier, L Yazdani… in Oncogene (2016)

  8. No Access

    Article

    High expression of EDAG and its significance in AML

    L-L An, G Li, K-F Wu, X-T Ma, G-G Zheng, L-G Qiu, Y-H Song in Leukemia (2005)

  9. No Access

    Article

    Production of matrix metalloproteinase-9 by cord blood CD34+ cells and its role in migration

    The transmigration of hematopoietic progenitor cells is a crucial step in the homing of transplanted stem cells into bone marrow (BM) microenvironment; however, the molecular basis for this is not fully unders...

    Q. Rao, G. G. Zheng, Y. M. Lin, K. F. Wu in Annals of Hematology (2004)

  10. No Access

    Article

    Gene transfer of pro-IL-18 and IL-1β converting enzyme cDNA induces potent antitumor effects in L1210 cells

    We report in a murine model of acute lymphoid leukemia L1210 the potent antitumor efficiency of a combinatorial delivery of pro-IL-18 gene modified L1210 (Lp18) and IL-1β converting enzyme (ICE) gene modified L12...

    B Zhang, K-F Wu, Y-M Lin, X-T Ma, Q Rao, G-G Zheng, Z-Y Cao, G Li, Y-H Song in Leukemia (2004)