43 Result(s)
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Open AccessClinical significance and prospective mechanism of increased CDKN2A expression in small cell lung cancer
Although it has been shown that cyclin dependent kinase inhibitor 2A (CDKN2A) plays a significant role in a number of malignancies, its clinicopathological value and function in small cell lung cancer (SCLC) i...
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Open AccessCorrection: c-Myc-driven glycolysis polarizes functional regulatory B cells that trigger pathogenic inflammatory responses
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Open AccessHeart-brain axis: low blood pressure during off-pump CABG surgery is associated with postoperative heart failure
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Open AccessMechanism of salidroside against coronary artery disease by network pharmacology analysis
Rosenroot (Rhodiola rosea) is a traditional Chinese herbal medicine. It has been used to treat patients with coronary artery disease (CAD). Salidroside is the main active constituent of rosenroot. This study w...
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Systematic Analysis of the Prognostic Significance and Roles of the Integrin Alpha Family in Non-Small Cell Lung Cancers
Lung cancer is one of the most common cancer malignancies and the principal cause of cancer-associated deaths worldwide. Non-small cell lung cancers (NSCLCs) account for more than 80% of all lung cancer cases....
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Open AccessIdentification through machine learning of potential immune- related gene biomarkers associated with immune cell infiltration in myocardial infarction
To investigate the potential role of immune-related genes (IRGs) and immune cells in myocardial infarction (MI) and establish a nomogram model for diagnosing myocardial infarction.
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Open AccessNeural responses to social decision-making in suicide attempters with mental disorders
Decision-making deficits have been reported in suicide attempters and may be a neuropsychological trait of vulnerability to suicidal behavior. However, little is known about how neural activity is altered in d...
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Brain-Computer Interfaces in Visualized Medicine
The brain-computer interface (BCI), also known as a brain-machine interface (BMI), has attracted extensive attention in biomedical applications. More importantly, BCI technologies have substantially revolution...
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Open AccessCorrection: Repair of osteochondral defect using icariin-conditioned serum combined with chitosan in rabbit knees
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Open AccessDownregulation of zinc finger protein 71 in laryngeal squamous cell carcinoma tissues and its potential molecular mechanism and clinical significance: a study based on immunohistochemistry staining and data mining
The molecular mechanism of laryngeal squamous cell carcinoma (LSCC) is not completely clear, which leads to poor prognosis and treatment difficulties for LSCC patients. To date, no study has reported the exact...
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Open AccessSARS-CoV-2 Spike protein promotes vWF secretion and thrombosis via endothelial cytoskeleton-associated protein 4 (CKAP4)
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Open AccessThe clinical significance of integrin subunit alpha V in cancers: from small cell lung carcinoma to pan-cancer
Little is known about the relationship between integrin subunit alpha V (ITGAV) and cancers, including small cell lung cancer (SCLC).
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Open AccessClinical assessment and molecular mechanism of the upregulation of Toll-like receptor 2 (TLR2) in myocardial infarction
The prevalence and mortality of cardiovascular diseases remain ranked first worldwide. Myocardial infarction (MI) is the central cause of death from cardiovascular diseases, seriously endangering human health....
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Open Accessc-Myc-driven glycolysis polarizes functional regulatory B cells that trigger pathogenic inflammatory responses
B cells secreting IL-10 functionally are recognized as functional regulatory B (Breg) cells; however, direct evidence concerning the phenotype, regulation, and functional and clinical relevance of IL-10-secreting...
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Open AccessSynergism of rMV-Hu191 with cisplatin to treat gastric cancer by acid sphingomyelinase-mediated apoptosis requiring integrity of lipid raft microdomains
DDP-based chemotherapy is one of the first-line treatment in GC. However, the therapeutic efficacy of DDP is limited due to side effects. Therefore, it is of great significance to develop novel adjuvants to sy...
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EEG-controlled functional electrical stimulation rehabilitation for chronic stroke: system design and clinical application
Stroke is one of the most serious diseases that threaten human life and health. It is a major cause of death and disability in the clinic. New strategies for motor rehabilitation after stroke are undergoing ex...
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B cell heterogeneity, plasticity, and functional diversity in cancer microenvironments
B cells constitute a major component of tumor-infiltrating leukocytes. However, the influence of these cells on malignancy is currently under debate, reflecting the heterogeneity of B cell subsets in tumors. W...
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Open AccessAltered spontaneous neural activity in the precuneus, middle and superior frontal gyri, and hippocampus in college students with subclinical depression
Subclinical depression (ScD) is a prevalent condition associated with relatively mild depressive states, and it poses a high risk of develo** into major depressive disorder (MDD). However, the neural patholo...
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Open AccessmiR-1249-5p regulates the osteogenic differentiation of ADSCs by targeting PDX1
Osteoporosis (OP) is an age-related systemic bone disease. MicroRNAs (miRNAs) are involved in the regulation of osteogenic differentiation. The purpose of this study was to explore the role and mechanism of mi...
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Open AccessRepair of osteochondral defect using icariin-conditioned serum combined with chitosan in rabbit knees
Osteochondral defects caused by an acute traumatic injury or articular degeneration remains difficult to be manipulated. Repair of articular defects is still a great challenge for both tissue engineers and ort...
