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    Reference Work Entry In depth

    Preclinical Models in Colorectal Cancer Drug Discovery

    Currently, colorectal cancer (CRC) remains one of the most common causes of cancer-related death worldwide despite advances in medical therapies of CRC. Therefore, appropriate animal models of CRC are urgently...

    Ying Yang, Wen-Jian Meng, Zi-Qiang Wang in Handbook of Animal Models and its Uses in … (2023)

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    Living Reference Work Entry In depth

    HER Receptor, Current, and Emerging Therapeutic Targets

    The human epidermal growth factor receptor (HER/ErbB) family consists of four members: HER-1 or epidermal growth factor receptor (EGFR), HER-2, HER-3, and HER-4. These receptors play a crucial role in regulati...

    Mei Lan Tan, Jia Wen Yeap, Azlinah Matawali in Handbook of Cancer and Immunology

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    Living Reference Work Entry In depth

    Endoplasmic Reticulum Stress and Emerging Therapeutic Targets in Cancer

    Endoplasmic reticulum stress (ER stress) is characterized by the accumulation of misfolded and unfolded proteins in the ER lumen. To mitigate the imbalanced ER protein-folding capacity, cells activate the unfo...

    Jia Wen Yeap, Mei Lan Tan in Handbook of Cancer and Immunology

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    Living Reference Work Entry In depth

    Preclinical Models in Colorectal Cancer Drug Discovery

    Currently, colorectal cancer (CRC) remains one of the most common causes of cancer-related death worldwide despite advances in medical therapies of CRC. Therefore, appropriate animal models of CRC are urgently...

    Ying Yang, Wen-Jian Meng, Zi-Qiang Wang in Handbook of Animal Models and its Uses in …