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    Construction and Analysis of miRNA Regulatory Networks

    This chapter is devoted to illustrate the usage of state-of-the-art methodologies for miRNA regulatory network construction and analysis. Advantages in understanding the role of miRNAs in regulating gene expre...

    Antonella Mensi, Vincenzo Bonnici, Simone Caligola in MicroRNA Target Identification (2019)

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    Recommendation Techniques for Drug–Target Interaction Prediction and Drug Repositioning

    The usage of computational methods in drug discovery is a common practice. More recently, by exploiting the wealth of biological knowledge bases, a novel approach called drug repositioning has raised. Several ...

    Salvatore Alaimo, Rosalba Giugno in Data Mining Techniques for the Life Scienc… (2016)

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    Computational Design of Artificial RNA Molecules for Gene Regulation

    RNA interference (RNAi) is a powerful tool for the regulation of gene expression. Small exogenous noncoding RNAs (ncRNAs) such as siRNA and shRNA are the active silencing agents, intended to target and cleave ...

    Alessandro Laganà, Dario Veneziano, Francesco Russo in RNA Bioinformatics (2015)