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    Protocol

    Uses of Telomerase Peptides in Anti-Tumor Immune Therapy

    Human telomerase reverse transcriptase (hTERT) represents a universal tumor-associated antigen to activate specific immune response in cancer immune therapy. Peptides derived from hTERT are presented by major ...

    He Li, Indzi Katik, Jun-** Liu in Telomerase Inhibition (2007)

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    Protocol

    Knockdown of Telomerase RNA Using Hammerhead Ribozymes and RNA Interference

    More than 85% of human cancers and over 70% of immortalized human cell lines have highly elevated telomerase activity. In contrast, telomerase activity is down-regulated in most human adult somatic cells, exce...

    Shang Li, Mehdi Nosrati, Mohammed Kashani-Sabet in Telomerase Inhibition (2007)

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    Protocol

    Inhibition of Telomerase by Targeting MAP Kinase Signaling

    Constitutive activation of the mitogen-activated protein (MAP) kinase signaling pathway by oncogenic stimulation is widespread in human cancers. With the recently demonstrated links between MAP kinase, histone...

    Dakang Xu, He Li, Jun-** Liu in Telomerase Inhibition (2007)