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    Protoplast Electrofusion and Regeneration in Potato

    Protoplast fusion and subsequent in vitro plant regeneration, leading to somatic hybridization, offer opportunities for transferring entire genomes from one plant into another, regardless of the interspecific ...

    Jian** Cheng, James A. Saunders in Plant Cell Electroporation and Electrofusion Protocols (1995)

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    MSACompro: Improving Multiple Protein Sequence Alignment by Predicted Structural Features

    Multiple Sequence Alignment (MSA) is an essential tool in protein structure modeling, gene and protein function prediction, DNA motif recognition, phylogenetic analysis, and many other bioinformatics tasks. Th...

    **n Deng, Jianlin Cheng in Multiple Sequence Alignment Methods (2014)

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    The MULTICOM Protein Tertiary Structure Prediction System

    With the expansion of genomics and proteomics data aided by the rapid progress of next-generation sequencing technologies, computational prediction of protein three-dimensional structure is an essential part o...

    Jilong Li, Debswapna Bhattacharya, Renzhi Cao in Protein Structure Prediction (2014)

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    Gene Delivery Method Using Photo-Responsive Poly(β-Amino Ester) as Vectors

    Nonviral vectors show great potential in delivering nucleic acids (NA) into many mammalian cells to achieve efficient gene transfection. Among these, cationic polymer is one of the most widely used nonviral ge...

    Nan Zheng, Yang Liu, Jianjun Cheng in Non-Viral Gene Delivery Vectors (2016)

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    Highly Efficient SiRNA Delivery Mediated by Cationic Helical Polypeptides and Polypeptide-Based Nanosystems

    RNA interference (RNAi) mediated by small interfering RNA (SiRNA) has recently emerged as a potent machinery in regulating gene expression at the post-translation step. Despite its efficiency and specificity, ...

    Lichen Yin, Nan Zheng, Jianjun Cheng in SiRNA Delivery Methods (2016)

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    Protein Residue Contacts and Prediction Methods

    In the field of computational structural proteomics, contact predictions have shown new prospects of solving the longstanding problem of ab initio protein structure prediction. In the last few years, application ...

    Badri Adhikari, Jianlin Cheng in Data Mining Techniques for the Life Sciences (2016)

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    Assessing Predicted Contacts for Building Protein Three-Dimensional Models

    Recent successes of contact-guided protein structure prediction methods have revived interest in solving the long-standing problem of ab initio protein structure prediction. With homology modeling failing for ...

    Badri Adhikari, Debswapna Bhattacharya in Prediction of Protein Secondary Structure (2017)

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    The Gene Balance Hypothesis: Epigenetics and Dosage Effects in Plants

    Dosage effects in plants are caused by changes in the copy number of chromosomes, segments of chromosomes, or multiples of individual genes. Genes often exhibit a dosage effect in which the amount of product i...

    **aowen Shi, Chen Chen, Hua Yang, Jie Hou, Tieming Ji in Plant Epigenetics and Epigenomics (2020)

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    The MULTICOM Protein Structure Prediction Server Empowered by Deep Learning and Contact Distance Prediction

    Prediction of the three-dimensional (3D) structure of a protein from its sequence is important for studying its biological function. With the advancement in deep learning contact distance prediction and residu...

    Jie Hou, Tianqi Wu, Zhiye Guo, Farhan Quadir, Jianlin Cheng in Protein Structure Prediction (2020)

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    Genetic Studies of Natural Glycosphingolipid Ligands for NKT Cells

    Glycosphingolipids (GSL) are natural ligands of NKT cells. Several laboratories have reported the in vitro activity of isoglobotriosylceramide (iGb3) in stimulating NKT cells. However, the knockout mice of iGb...

    Dapeng Zhou, Chengfeng **a, Peng G. Wang, Zhiyuan Li in Invariant Natural Killer T-Cells (2021)