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    Xenograft Models in Immunodeficient Animals

    The growth of metastases is the end result of a multistep process in which cancer cells invade through basement membranes, extravasate into bloodstream or lymphatic vessels, survive transit in the circulation,...

    Janet E. Price in Metastasis Research Protocols (2001)

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    Clinically Relevant Metastatic Breast Cancer Models to Study Chemosensitivity

    Metastatic disease, notably to the lungs, liver, bone, and brain, is the most common cause of death from breast cancer, despite advances in surgical and clinical management. Two basic principles govern the pro...

    Lee Su Kim, Janet E. Price in Chemosensitivity: Volume II (2005)

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    Spontaneous and Experimental Metastasis Models: Nude Mice

    Immunodeficient mice are widely used for cancer research as they can provide an in vivo system in which to study the tumorigenicity and metastatic potential of human cancer cells. The athymic or “nude” mouse h...

    Janet E. Price in Metastasis Research Protocols (2014)