3 Result(s)
within
Protocol
Aaron M. Rosenfeld
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Protocol
Adaptive Immune Receptor Repertoire (AIRR) Community Guide to Repertoire Analysis
Adaptive immune receptor repertoires (AIRRs) are rich with information that can be mined for insights into the workings of the immune system. Gene usage, CDR3 properties, clonal lineage structure, and sequence...
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Protocol
Adaptive Immune Receptor Repertoire (AIRR) Community Guide to TR and IG Gene Annotation
High-throughput sequencing of adaptive immune receptor repertoires (AIRR, i.e., IG and TR) has revolutionized the ability to carry out large-scale experiments to study the adaptive immune response. Since the m...
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Protocol
Bulk gDNA Sequencing of Antibody Heavy-Chain Gene Rearrangements for Detection and Analysis of B-Cell Clone Distribution: A Method by the AIRR Community
In this method we illustrate how to amplify, sequence, and analyze antibody/immunoglobulin (IG) heavy-chain gene rearrangements from genomic DNA that is derived from bulk populations of cells by next-generatio...
