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    Protocol

    In Vitro Conversion of Murine Fibroblasts into Cardiomyocyte-Like Cells

    Direct reprogramming of fibroblasts into induced cardiomyocytes (iCMs) holds great promise as a potential treatment for cardiovascular disease, many of which are associated with tremendous loss of functional c...

    Jun Xu, Li Wang, Jiandong Liu, Li Qian in Cardiac Regeneration (2021)

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    Protocol

    Direct Cardiac Reprogramming as a Novel Therapeutic Strategy for Treatment of Myocardial Infarction

    Direct reprogramming of fibroblasts into induced cardiomyocytes (iCMs) holds great promise as a novel therapy for the treatment of heart failure, a common and morbid disease that is usually caused by irreversi...

    Hong Ma, Li Wang, Jiandong Liu, Li Qian Ph.D. in Cardiac Gene Therapy (2017)

  3. No Access

    Protocol

    In Silico and Wet-Bench Identification of Nuclear Matrix Attachment Regions

    Chromatin loops are tethered at discrete regions that are approx 100-1000 bp in length. These regions of attachment serve as specific sequence landmarks, anchoring the DNA to the fibers of the chromosomal scaf...

    Stephen A. Krawetz, Sorin Draghici, Robert Goodrich, Zhandong Liu… in Hypertension (2005)