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Chapter and Conference Paper
Investigation of Seawater Exchange Rate for Coastal Protection Structures
Various types of erosion prevention facilities installed for the purpose of protecting the beach have been proposed in order to effectively control the waves and wave induced current as well as being installed...
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Chapter and Conference Paper
QTL Map** of Gray Leaf Spot Resistance in Ryegrass, and Synteny-based Comparison with Rice Blast Resistance Genes in Rice
Gray leaf spot (GLS) is a serious fungal disease recently reported on the important turfgrass and forage species, perennial ryegrass (Lolium perenne) caused by Magnaporthe grisea, which also causes rice blast and...
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Chapter and Conference Paper
Intralesional radioimmunotherapy in the treatment of malignant glioma: clinical and experimental findings
In the last two decades radioimmunotherapy has been used as an additional treatment option for malignant glioma in several centers. More than 400 patients have been reported, who were treated in the framework ...
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Chapter and Conference Paper
Veränderung der Hepatitis C induzierten Zytokinproduktion durch die HIV-Koinfektion
Hintergrund: Epidemiologische Daten zeigen, daß die Hepatitis C Virusinfektion (HCV) bei gleichzeitiger HIV-Koinfektion, vermutlich infolge einer veränderten zellulären Immunantwort, einen raschere...
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Chapter and Conference Paper
The Single Cysteinyl Residue (Cys341) of Carboxypeptidase Y for Cavity Control in the S1 Substrate Binding Pocket
Role of a single sulfhydryl group (Cys341) in carboxypeptidase Y (CPY) was investigated by combining site-directed mutagenesis and high-pressure techniques. ΔV ǂ in the CPY catalyzed hydrolysis of F...
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Chapter and Conference Paper
Synthetic Lipopeptides of Bacterial Origin as Novel and Efficient Adjuvants for Parenteral and Oral Immunization
Lipopeptides of bacterial origin constitute potent immunoadjuvants in vitro and in vivo when given in combination with antigens [1–3]. Parenteral application of the lipopeptide P3CSK4, shown in Fig. 1, enhanced t...
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Chapter and Conference Paper
Target Cell Induced T Cell Activation with Bispecific Antibodies: A New Concept for Tumor Immunotherapy
It can hardly be disputed that current treatment of malignant tumors with radiotherapy or cytotoxic drugs fails to produce cure or long-term remission in a large majority of patients, tumors of the nervous sys...
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Chapter and Conference Paper
Exotic Manifestations of Intrinsic High-T c Interferometer Loops
Experimental evidence for intrinsic quantum interferometer loops in YBaCuO thin films was obtained from the microwave emission, magnetoresistance quantization, and low frequency noise 2 measurements. The avera...
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Chapter and Conference Paper
Low Noise UHF Thin Film SQUID with Cryogenic HEMT Preamplifier
The design and performance of UHF thin film RF SQUID system employing a cryogenic RF preamplifier is described. The flux noise of the magnetometer is ...
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Chapter and Conference Paper
Prostate Cancer: A Retrospective Evaluation of Radiotherapy in French Cancer Institutes
The study reported here was undertaken by the French Federation of Anticancer Institutes. In 1985 results were reported [1] from six participating Institutes on 597 cases of prostate cancer treated exclusively...
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Chapter and Conference Paper
Bacterial Surface Components as Immunomodulators
Synthetically prepared derivatives of the cell wall of Gram-negative bacteria were tested for their immunomodulatory properties in mice. Besides being able to activate splenic B cells polyclonally, as demonstr...
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Chapter and Conference Paper
Generation of Pre-Neocarzinostatin and Its Antagonistic Effect on Neocarzinostatin-Induced DNA Strand Scission
Pretreatment of the antitumor protein neocarzinostatin (NCS) with heat, UV or room light, and sulfhydryl reagents inactivates the drug, as measured by the cessation of phage T2 DNA strand scission in vitro. Th...
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Chapter and Conference Paper
Structural Requirements for Membrane Modifying Activity in Alamethicin-Type Antibiotics
In order to elucidate the relations between structure and membrane modifying properties of alamethicin-type antibiotics investigations with natural, modified natural and synthetic analogues have been carried o...
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Chapter and Conference Paper
A New Model for the Activation and Inactivation of Neocarzinostatin, an Antitumor Protein
Neocarzinostatin (NCS), an antibiotic protein exhibits therapeutic activity against a variety of tumors, most notably acute leukemia in man. The protein has a MW of 10,700 and the known amino acid sequence inc...
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Chapter and Conference Paper
Aminopeptidasen und andere Enzyme im Ovar des Menschen
In menschlichen Ovarien zeigen im Verlauf des Cyclus Aldolase, Glucose-6-phosphat-Dehydrogenase, alkalische Phosphatase, sog. Leucin-aminopeptidase, Lactatdehydrogenase, Malatdehydrogenase sowie Glutamat-Oxala...
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Chapter and Conference Paper
Enzymuntersuchungen im Liquor folliculi
Wir sind heute weitgehend über die physiologischen und hormonellen Vorgänge des weiblichen Cyclus informiert. Es ist möglich, in diesen Cyclus einzugreifen und ihn zu verändern. Dabei können auch die Reifung d...